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Diane Pennica

from Dana Point, CA
Age ~73
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Also known as:
Diane Penica, Diane Mw Pennica
Phone and address:
32331 Caribbean Dr, Dana Point, CA 92629
(650) 245-9740
Connected to:
Jesse P Pennica, 43Austin P Pennick, 38Bruce J Pennick, 65Christopher D Pennick, 41Craig A Pennick, 59Henry Pennick, 72Herbert G Pennick, 79Kim Pennick, 66Michael D Pennick, 63Daidre Pennicooke, 46

Diane Pennica Phones & Addresses

  • 32331 Caribbean Dr, Dana Point, CA 92629 (650) 245-9740
  • Monarch Bay, CA
  • Foster City, CA
  • 2417 Hale Dr, Burlingame, CA 94010 (650) 343-3813 (650) 943-3818

Resumes

Resumes

Diane Pennica Photo 1

Diane Pennica

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Location:
32331 Caribbean Dr, Dana Point, CA 92629
Industry:
Biotechnology
Work:
Genentech
Retired Senior Scientist
Education:
University of Rhode Island 1973 - 1977
Doctorates, Doctor of Philosophy, Microbiology, Philosophy State University of New York at Fredonia
Doctorates, Doctor of Philosophy, Philosophy
Skills:
Biotechnology
Drug Discovery
Assay Development
Monoclonal Antibodies
Molecular Biology
Drug Development
Protein Chemistry
Biochemistry
Immunology
Cell Biology
Oncology
Antibodies
Genomics
Cell Culture
Lifesciences
Cell
Biomarkers
Western Blotting
Tissue Culture
Cancer
Cross Functional Team Leadership
Cancer Research
Life Sciences
Languages:
English
Diane Pennica Photo 2

Senior Scientist At Genentech, Inc

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Position:
Senior Scientist at Genentech, Inc
Location:
San Francisco Bay Area
Industry:
Research
Work:
Genentech, Inc since May 1980
Senior Scientist
Education:
University of Rhode Island

Publications

Us Patents

Wisp Polypeptides And Nucleic Acids Encoding Same

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US Patent:
6387657, May 14, 2002
Filed:
Oct 29, 1998
Appl. No.:
09/182145
Inventors:
David A. Botstein - Belmont CA
Robert L. Cohen - San Mateo CA
Audrey D. Goddard - San Francisco CA
Austin L. Gurney - Belmont CA
Kenneth J. Hillan - San Francisco CA
David A. Lawrence - San Francisco CA
Arnold J. Levine - New York NY
Diane Pennica - Burlingame CA
Margaret Ann Roy - San Francisco CA
William I. Wood - Hillsborough CA
Assignee:
Genentech, Inc. - South San Francisco CA
International Classification:
C12N 1512
US Classification:
435 691, 435 694, 435325, 435358, 435243, 43525233, 4352551, 4353201, 536 231, 536 235, 536 2351
Abstract:
Wnt-1-Induced Secreted Proteins (WISPs) are provided, whose genes are induced at least by Wnt-1. Also provided are nucleic acid molecules encoding those polypeptides, as well as vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides, and methods for producing the polypeptides.

Cardiotrophin-1 Defective Mouse

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US Patent:
6472585, Oct 29, 2002
Filed:
Aug 25, 2000
Appl. No.:
09/648183
Inventors:
David Botstein - Belmont CA
Audrey Goddard - San Francisco CA
David A. Lawrence - San Francisco CA
Diane Pennica - Burlingame CA
Margaret Ann Roy - San Francisco CA
William I. Wood - Hillsborough CA
Assignee:
Genentech, Inc. - South San Francisco CA
International Classification:
A01K 67027
US Classification:
800 18, 800 21, 800 3
Abstract:
The invention concerns composititions and methods for the diagnosis and treatment of neoplastic cell growth and proliferation in mammals, including humans. The invention is based on the identification of cardiotrophin-1 gene amplified in the genome of tumor cells. Such gene amplification is expected to be associated with the overexpression of the gene product and contribute to tumorigenesis. Accordingly, the cardiotrophin-1 polypeptide encoded by the amplified gene is believed to be a useful target for the diagnosis and/or treatment (including prevention) of certain cancers, and may act as a predictor of the prognosis of tumor treatment.

Guanylate-Binding Protein

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US Patent:
6642024, Nov 4, 2003
Filed:
Aug 17, 2000
Appl. No.:
09/643657
Inventors:
Diane Pennica - Burlingame CA
Assignee:
Genentech Inc. - South San Francisco CA
International Classification:
C12P 2106
US Classification:
435 691, 4353201, 4352523, 435325, 536 231, 530350
Abstract:
A member of the guanylate-binding protein family, designated GBP-4, is provided. Also provided are isolated nucleic acid encoding GBP-4, vectors and host cells containing such nucleic acid molecule, and a method for producing the GBP-4 recombinantly.

Wnt-Regulated Cytokine-Like Polypeptide And Nucleic Acids Encoding Same

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US Patent:
7005499, Feb 28, 2006
Filed:
Nov 16, 2000
Appl. No.:
09/715418
Inventors:
David A. Lewin - New Haven CT, US
Diane Pennica - Burlingame CA, US
Luca Rastelli - Guilford CT, US
Bruce Taillon - Middletown CT, US
Assignee:
Genentech, Inc. - South San Francisico CA
Curagen Corporation - New Haven CT
International Classification:
C07K 14/47
US Classification:
530350
Abstract:
The present invention provides novel polypeptides, termed FCTRX polypeptides, as well as polynucleotides encoding FCTRX polypeptides and antibodies that immunospecifically bind to an FCTRX or a derivative, variant, mutant, or fragment of an FCTRX polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the FCTRX polypeptide, polynucleotide and antibody are used in detection and treatment of a broad range of pathological states, as well as to other uses.

Guanylate-Binding Protein

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US Patent:
7091178, Aug 15, 2006
Filed:
Sep 10, 2003
Appl. No.:
10/659549
Inventors:
Diane Pennica - Burlingame CA, US
Assignee:
Genentech, Inc. - South San Francisco CA
International Classification:
C07K 14/00
US Classification:
514 2, 530350
Abstract:
A member of the guanylate-binding protein family, designated GBP-4, is provided. Also provided are isolated nucleic acid encoding GBP-4, vectors and host cells containing such nucleic acid molecule, and a method for producing the GBP-4 recombinantly.

Wisp Polypeptides And Nucleic Acids Encoding Same

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US Patent:
7101850, Sep 5, 2006
Filed:
Mar 27, 2002
Appl. No.:
10/112267
Inventors:
Arnold J. Levine - New York NY, US
Diane Pennica - Burlingame CA, US
Assignee:
Genentech, Inc. - South San Francisco CA
International Classification:
A61K 38/00
US Classification:
514 12, 530350
Abstract:
Wnt-1-Induced Secreted Proteins (WISPs) are provided, whose genes are induced at least by Wnt-1. Also provided are nucleic acid molecules encoding those polypeptides, as well as vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides, and methods for producing the polypeptides.

Human Tpa Production Using Vectors Coding For Dhfr Protein

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US Patent:
H002181, Feb 6, 2007
Filed:
Feb 28, 1991
Appl. No.:
07/663244
Inventors:
Arthur D. Levinson - Hillsborough CA, US
Diane Pennica - Burlingame CA, US
William J. Kohr - San Mateo CA, US
Gordon A. Vehar - San Carlos CA, US
David V. Goeddel - Hillsborough CA, US
Elizabeth M. Yelverton - Seattle WA, US
Christian C. Simonsen - Saratoga CA, US
Assignee:
Genentech, Inc. - San Francisco CA
International Classification:
C12N 15/09
US Classification:
435 692
Abstract:
A method for producing tissue plasminogen activator (t-PA) in eukaryotic host cells is disclosed. Enhanced levels of t-PA production are obtained by co-amplification of the t-PA gene through treatment of cultures transformed with mutant or wild-type DHFR with methotrexate.

Stra6 Polypeptides

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US Patent:
7173115, Feb 6, 2007
Filed:
Jan 11, 2001
Appl. No.:
09/759056
Inventors:
Diane Pennica - Burlingame CA, US
Victoria Smith - Burlingame CA, US
William I. Wood - Cupertino CA, US
Assignee:
Genentech, Inc. - South San Francisco CA
International Classification:
C07H 21/02
C07H 21/04
C12Q 1/68
US Classification:
536 231, 536 241, 536 253, 435 691, 4353201
Abstract:
The present invention is directed to novel polypeptides having sequence similarity to Stra6, a murine retinoic acid responsive protein, and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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Diane Pennica from Dana Point, CA, age ~73 Get Report