Search

Deep Singh Phones & Addresses

  • Waltham, MA
  • Cambridge, MA
  • Allston, MA
  • Somerville, MA
  • Denver, CO
  • King of Prussia, PA

Publications

Us Patents

Multi-Directional Microfluidic Drug Delivery Device

View page
US Patent:
20130035560, Feb 7, 2013
Filed:
Aug 1, 2012
Appl. No.:
13/563785
Inventors:
PJ Anand - Ayer MA, US
Deep Arjun Singh - Cambridge MA, US
Assignee:
ALCYONE LIFESCIENCES, INC. - Ayer MA
International Classification:
A61M 25/14
A61B 5/01
A61B 5/03
A61B 5/145
A61M 5/142
A61M 1/00
US Classification:
600301, 604151, 604173, 604 35, 604500, 600561, 600365, 600309, 600364, 600549
Abstract:
The methods, systems, and devices disclosed herein generally involve convection-enhanced delivery of drugs to a target region within a patient. Microfluidic catheter devices are disclosed that are particularly suitable for targeted delivery of drugs via convection, including devices capable of multi-directional drug delivery, devices that control fluid pressure and velocity using the venturi effect, and devices that include conformable balloons. Methods of treating various diseases using such devices are also disclosed, including methods of treating cerebral and spinal cavernous malformations, cavernomas, and hemangiomas, methods of treating neurological diseases, methods of treatment using multiple microfluidic delivery devices, methods of treating hearing disorders, methods of spinal drug delivery using microfluidic devices, and methods of delivering stem cells and therapeutics during fetal surgery. Methods of manufacturing such devices are also disclosed.

Fluid Delivery Systems And Methods Of Treatment

View page
US Patent:
20220379010, Dec 1, 2022
Filed:
May 19, 2022
Appl. No.:
17/748199
Inventors:
- Lowell MA, US
Mohammadreza Khani - Moscow ID, US
Lucas Sass - Moscow ID, US
Ostin Arters - Moscow ID, US
Stuart Sater - Troy ID, US
Deep Arjun Singh - Cambridge MA, US
PJ Anand - Lowell MA, US
Thomas T. Washburn - Lancaster MA, US
Krishna Subramanian - Mechanicsville VA, US
International Classification:
A61M 5/14
A61M 5/168
A61M 5/00
A61M 5/172
C12N 15/113
Abstract:
The disclosed systems and methods are configurable central nervous system (CNS) delivery solutions for therapeutics, such as genetic medicines. The systems and methods first infuse a therapeutic bolus within intrathecal space and subsequently infuse a flush fluid to move the therapeutic bolus rostrally toward a target area and achieve a desired spread in the spine and/or brain. The second location can be at a location caudal to the delivery location of the therapeutic bolus.

Fluid Delivery Systems And Methods Of Treatment

View page
US Patent:
20220370710, Nov 24, 2022
Filed:
May 19, 2022
Appl. No.:
17/748246
Inventors:
- Lowell MA, US
Mohammadreza Khani - Moscow ID, US
Lucas Sass - Moscow ID, US
Ostin Arters - Moscow ID, US
Stuart Sater - Troy ID, US
Deep Arjun Singh - Cambridge MA, US
Pj Anand - Lowell MA, US
Thomas T. Washburn - Lancaster MA, US
Krishna Subramanian - Mechanicsville VA, US
International Classification:
A61M 5/142
A61M 5/172
A61M 25/00
A61M 39/02
Abstract:
The disclosed systems and methods are configurable central nervous system (CNS) delivery solutions for therapeutics, such as genetic medicines. The systems and methods first infuse a therapeutic bolus within intrathecal space and subsequently infuse a flush fluid to move the therapeutic bolus rostrally toward a target area and achieve a desired spread in the spine and/or brain. The second location can be at a location caudal to the delivery location of the therapeutic bolus.

Fluid Delivery Systems And Methods Of Treatment

View page
US Patent:
20220370716, Nov 24, 2022
Filed:
May 19, 2022
Appl. No.:
17/748221
Inventors:
- Lowell MA, US
Mohammadreza Khani - Moscow ID, US
Lucas Sass - Moscow ID, US
Ostin Arters - Moscow ID, US
Stuart Sater - Troy ID, US
Deep Arjun Singh - Cambridge MA, US
PJ Anand - Lowell MA, US
Thomas T. Washburn - Lancaster MA, US
Krishna Subramanian - Mechanicsville VA, US
International Classification:
A61M 5/172
A61M 5/00
A61K 31/713
Abstract:
The disclosed systems and methods are configurable central nervous system (CNS) delivery solutions for therapeutics, such as genetic medicines. The systems and methods first infuse a therapeutic bolus within intrathecal space and subsequently infuse a flush fluid to move the therapeutic bolus rostrally toward a target area and achieve a desired spread in the spine and/or brain. The second location can be at a location caudal to the delivery location of the therapeutic bolus.

Fixation Devices For Catheters

View page
US Patent:
20220241559, Aug 4, 2022
Filed:
Jan 28, 2022
Appl. No.:
17/588087
Inventors:
- Lowell MA, US
Burt Raymond - Nashua NH, US
Andre Carline Wood - Worchester MA, US
Deep Arjun Singh - Cambridge MA, US
Jonathan Freund - Woburn MA, US
John L. Mcguire - Westborough MA, US
Krishna Subramanian - Mechanicsville VA, US
Matthew J. Lapinski - Lowell MA, US
Megan Holmes - Cambridge MA, US
Thomas T. Washburn - Lancaster MA, US
International Classification:
A61M 25/02
Abstract:
Fixation devices are disclosed herein that can be used to secure to a catheter and to tissue. The fixation devices include a body having a bore extending therethrough to receive a catheter. The fixation devices can also include suture openings or grooves to secure the devices to tissue.

Shunt Flushers And Related Methods

View page
US Patent:
20210093844, Apr 1, 2021
Filed:
Oct 5, 2020
Appl. No.:
17/062815
Inventors:
- Lowell MA, US
Deep Arjun Singh - Cambridge MA, US
Greg Eberl - Acton MA, US
Andrew East - Arlington MA, US
Morgan Brophy - Somerville MA, US
Ayesha Arzumand - North Billerica MA, US
Stela Moura - Lowell MA, US
Loredana Guseila - Lowell MA, US
Assignee:
Anuncia, Inc. - Lowell MA
International Classification:
A61M 27/00
A61M 39/22
Abstract:
Systems and methods for flushing shunt systems are disclosed herein. In some embodiments, a flusher includes a pinch tube that extends over a flush dome such that a user can simultaneously close the pinch tube and actuate the flush dome with a single motion. Flushing and refill valves of the system can be disposed in a cartridge that is laterally-offset from the flush dome, advantageously reducing the height profile of the flusher. Flushers with integrated shunt valves are also disclosed, as are shunt systems with restricted and unrestricted modes for selectively limiting the instances in which a user can open an auxiliary flow path through the system.

Fluid Delivery System

View page
US Patent:
20210060326, Mar 4, 2021
Filed:
Aug 27, 2020
Appl. No.:
17/004470
Inventors:
- Lowell MA, US
Deep Arjun Singh - Cambridge MA, US
Andrew East - Lowell MA, US
Thomas T. Washburn - Lancaster MA, US
Megan Holmes - Cambridge MA, US
International Classification:
A61M 39/02
Abstract:
The fluid delivery devices, systems and methods described herein include a subcutaneous port, a catheter, and a connection assembly configured to fluidly couple the port and catheter.

Automated Drug Delivery Systems And Methods

View page
US Patent:
20210052820, Feb 25, 2021
Filed:
Nov 9, 2020
Appl. No.:
16/949661
Inventors:
- Lowell MA, US
Ayesha Arzumand - North Billerica MA, US
Morgan Brophy - Boston MA, US
Andrew East - Lowell MA, US
Gregory Eberl - Acton MA, US
Deep Arjun Singh - Cambridge MA, US
International Classification:
A61M 5/315
A61M 5/145
A61M 5/20
A61M 5/32
Abstract:
Automated drug delivery systems and related methods are disclosed herein. In some embodiments, these systems can reduce or eliminate infusion inconsistencies. An exemplary system can include a syringe actuator which can be controlled via electrical, mechanical, pneumatic, and/or hydraulic means to precisely infuse and/or withdraw material from a patient.
Deep A Singh from Waltham, MA, age ~39 Get Report