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David Shortle Phones & Addresses

  • 18 Seminole Ave, Catonsville, MD 21228 (410) 719-2114
  • Baltimore, MD
  • Tipton, IN
  • Seattle, WA
  • Port Jefferson, NY
  • Stony Brook, NY

Work

Company: The johns hopkins university school of medicine Position: Professor

Education

Degree: High school graduate or higher

Industries

Railroad Manufacture

Resumes

Resumes

David Shortle Photo 1

Professor At The Johns Hopkins University School Of Medicine

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Location:
319 Ringold Valley Cir, Cockeysville, MD 21030
Industry:
Railroad Manufacture
Work:
The Johns Hopkins University School of Medicine
Professor

Publications

Us Patents

Synthesis Of Diverse And Useful Collections Of Oligonucleotidies

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US Patent:
58696440, Feb 9, 1999
Filed:
Aug 8, 1996
Appl. No.:
8/689346
Inventors:
David R. Shortle - Baltimore MD
John Sondek - New Haven CT
Assignee:
The Johns Hopkins University - Baltimore MD
International Classification:
C07H 2100
C12N 1500
US Classification:
536 253
Abstract:
A new technique for generating mixtures of oligonucleotides in a single automated synthesis is taught. The method can be used to prepare mixed oligonucleotides ideally suited for creation of useful mixtures of oligo- or polypeptides or proteins. Additionally, the technique enables insertion and/or substitution and/or deletion of a nucleotide sequence at one or more sites. For protein mutagenesis, a trinucleotide can be inserted or substituted at codon boundaries. The invented technique makes possible the encoding of all possible single amino acid insertions, or any desired mixture of substitutions and insertions.
David R Shortle from Catonsville, MD, age ~76 Get Report