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Dasa Lipovsek

from Pepperell, MA
Age ~59
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Also known as:
Dasa Sali, Dasa E, Dasa K
Phone and address:
13 Maple St, East Pepperell, MA 01463
Related to:
Deborah S Persaud, 64
Connected to:
Peter J Lipovsek, 57Amelia B Lipovsky, 34Elizabeth A Lipovsky, 37Igor Lipovsky, 74Lizzie Lipovsky, 73Lynn M Lipovsky, 65Olga Lipovski, 56Robert E Lipovsky, 77Mark A Lipowicz, 67Harvey P Lipowitz, 72

Dasa Lipovsek Phones & Addresses

  • 13 Maple St, Pepperell, MA 01463
  • Antrim, NH
  • 45 Sunset Rd, Cambridge, MA 02138 (617) 497-9077
  • 43 Sunset Rd, Cambridge, MA 02138
  • Scotch Plains, NJ
  • New York, NY
  • Queens Village, NY
  • Elizabeth, NJ

Publications

Us Patents

Protein Scaffolds For Antibody Mimics And Other Binding Proteins

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US Patent:
7115396, Oct 3, 2006
Filed:
Dec 3, 2003
Appl. No.:
10/728078
Inventors:
Dasa Lipovsek - Cambridge MA, US
Richard W. Wagner - Concord MA, US
Robert G. Kuimelis - Brighton MA, US
Assignee:
Compound Therapeutics, Inc. - Waltham MA
International Classification:
A61K 38/00
US Classification:
435 691
Abstract:
Disclosed herein are proteins that include an immunoglobulin fold and that can be used as scaffolds. Also disclosed herein are nucleic acids encoding such proteins and the use of such proteins in diagnostic methods and in methods for evolving novel compound-binding species and their ligands.

Fibronectin Based Scaffold Domain Proteins That Bind To Pcsk9

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US Patent:
8420098, Apr 16, 2013
Filed:
Apr 13, 2011
Appl. No.:
13/085864
Inventors:
Ray Camphausen - Wayland MA, US
Jonathan H. Davis - Auburndale MA, US
Sharon T. Cload - Cambridge MA, US
Fabienne M. Denhez - Arlington MA, US
Dasa Lipovsek - Cambridge MA, US
Ching-Hsiung Frederick Lo - Pennington NJ, US
Chee Meng Low - Allston MA, US
Bowman Miao - Churchville PA, US
Tracy S. Mitchell - Billerica MA, US
Rex A. Parker - Titusville NJ, US
Ginger C. Rakestraw - Cambridge MA, US
Katie A. Russo - Watertown MA, US
Doree F. Sitkoff - Dresher PA, US
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
A61K 39/00
C07K 1/00
US Classification:
4241851, 530382
Abstract:
The present invention relates to fibronectin based scaffold domain proteins that bind PCSK9. The invention also relates to the use of the innovative proteins in therapeutic applications to treat atherosclerosis, hypercholesterolemia and other cholesterol related diseases. The invention further relates to cells comprising such proteins, polynucleotides encoding such proteins or fragments thereof, and to vectors comprising the polynucleotides encoding the innovative protein.

Methods For Producing Nucleic Acids Lacking 3'-Untranslated Regions And Optimizing Cellular Rna -Protein Fusion Formation

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US Patent:
20020160377, Oct 31, 2002
Filed:
Jul 20, 2001
Appl. No.:
09/910518
Inventors:
Philip Hammond - Ayer MA, US
Dasa Lipovsek - Cambridge MA, US
International Classification:
C12Q001/68
C07H021/02
C07H021/04
US Classification:
435/006000, 536/023100
Abstract:
Described herein are methods for removing the 3′-untranslated regions from cDNA or mRNA molecules, as well as methods for the use of such products for RNA-protein fusion formation.

Methods For Producing Nucleic Acids Lacking 3'-Untranslated Regions And Optimizing Cellular Rna-Protein Fusion Formation

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US Patent:
20040086980, May 6, 2004
Filed:
Aug 21, 2003
Appl. No.:
10/646985
Inventors:
Philip Hammond - Ayer MA, US
Dasa Lipovsek - Cambridge MA, US
International Classification:
C12P019/34
C12N015/85
US Classification:
435/091200, 435/455000
Abstract:
Described herein are methods for removing the 3′-untranslated regions from cDNA or mRNA molecules, as well as methods for the use of such products for RNA-protein fusion formation.

Serum Albumin Scaffold-Based Proteins And Uses Thereof

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US Patent:
20050079546, Apr 14, 2005
Filed:
May 3, 2004
Appl. No.:
10/838311
Inventors:
Dasa Lipovsek - Cambridge MA, US
Lin Sun - West Roxbury MA, US
Alexander Kovtun - Acton MA, US
International Classification:
G01N033/53
G01N033/543
C07K014/765
US Classification:
435007100, 436518000, 530363000
Abstract:
Disclosed herein are libraries of candidate binding proteins derived from a serum albumin scaffold, from which useful binding proteins may be selected that are specific for known and unknown targets. Also disclosed herein are methods for selection of serum albumin scaffold-based candidate binding proteins which possess such desired binding characteristics.

Protein Scaffolds For Antibody Mimics And Other Binding Proteins

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US Patent:
20050255548, Nov 17, 2005
Filed:
Nov 15, 2004
Appl. No.:
10/989723
Inventors:
Dasa Lipovsek - Cambridge MA, US
Richard Wagner - Concord MA, US
Robert Kuimelis - Brighton MA, US
International Classification:
C07H021/04
C12P021/06
C07K014/745
US Classification:
435069100, 435320100, 435325000, 536023500, 530382000
Abstract:
Disclosed herein are proteins that include a fibronectin type III domain having at least one randomized loop. Also disclosed herein are nucleic acids encoding such proteins and the use of such proteins in diagnostic methods and in methods for evolving novel compound-binding species and their ligands.

Pharmaceutically Acceptable Fn3 Polypeptides For Human Treatments

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US Patent:
20060246059, Nov 2, 2006
Filed:
Jul 7, 2006
Appl. No.:
11/483918
Inventors:
Dasa Lipovsek - Cambridge MA, US
Richard Wagner - Concord MA, US
Robert Kuimelis - Palo Alto CA, US
Assignee:
Compound Therapeutics, Inc. - Waltham MA
International Classification:
A61K 39/395
C07K 16/46
C12N 1/21
C12P 21/04
US Classification:
424133100, 514012000, 435069700, 435320100, 435325000, 435252300, 530391100
Abstract:
Disclosed herein are proteins that include an immunoglobulin fold and that can be used as scaffolds. Also disclosed herein are nucleic acids encoding such proteins and the use of such proteins in diagnostic methods and in methods for evolving novel compound-binding species and their ligands.

Pharmaceutical Preparations Of Fn3 Polypeptides For Human Treatments

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US Patent:
20060270604, Nov 30, 2006
Filed:
Jul 7, 2006
Appl. No.:
11/483808
Inventors:
Dasa Lipovsek - Cambridge MA, US
Richard Wagner - Concord MA, US
Robert Kuimelis - Palo Alto CA, US
Assignee:
Compound Therapeutics, Inc. - Waltham MA
International Classification:
A61K 38/36
US Classification:
514012000
Abstract:
Disclosed herein are proteins that include an immunoglobulin fold and that can be used as scaffolds. Also disclosed herein are nucleic acids encoding such proteins and the use of such proteins in diagnostic methods and in methods for evolving novel compound-binding species and their ligands.
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Dasa Lipovsek from Pepperell, MA, age ~59 Get Report