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Chiajen J Lai

from Livermore, CA
Age ~56
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Also known as:
Chia Jen Lai, Chia J Lai, Chia-Jen Lai, Jen Lai Chia, Lai Chiajen, Lai Chia-Jen, Lia Chaigen
Phone and address:
3243 Edinburgh Dr, Livermore, CA 94551
Related to:
Jonathon Lai
Connected to:
Adeline C Lai, 51Allen H Lai, 48Angelica Y Lai, 34Barbara E Lai, 74Bon G Lai, 69Catherine R Lai, 76Cecilia Lai, 94Cedric W Lai, 70Chinh D Lai, 61Chising C Lai, 65

Chiajen Lai Phones & Addresses

  • 3243 Edinburgh Dr, Livermore, CA 94551
  • South Brunswick, NJ
  • 24 Labrador Dr, Kendall Park, NJ 08824 (732) 297-2930
  • Princeton, NJ

Work

Company: Gilead sciences Nov 2018 Position: Senior director - process chemistry development

Education

Degree: Doctorates, Doctor of Philosophy School / High School: Princeton University 1994 to 1999 Specialities: Chemical Engineering, Philosophy

Skills

Pharmaceutical Industry • Drug Development • Technology Transfer • Quality By Design • Gmp • Drug Delivery • Formulation • Drug Discovery • R&D • Biopharmaceuticals • Clinical Development • Validation • Glp • Hplc • Pharmaceutics • Organic Chemistry • Biotechnology • Ind • Analytical Chemistry • Fda • Organic Synthesis • Chromatography • Research and Development • Cmc • Project Management • 21 Cfr Part 11 • Change Control • Strategic Planning • Medicinal Chemistry • Purification • Lc Ms • Sop • Regulatory Submissions • Regulatory Affairs • Pharmacokinetics • V&V • Oncology • Cro • Dissolution • Clinical Trials • Lims • Pharmaceutical Research • Standard Operating Procedure

Languages

English

Industries

Pharmaceuticals

Resumes

Resumes

Chiajen Lai Photo 1

Senior Director - Process Chemistry Development

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Location:
3243 Edinburgh Dr, Livermore, CA 94551
Industry:
Pharmaceuticals
Work:
Gilead Sciences
Senior Director - Process Chemistry Development
Gilead Sciences Jun 2014 - Oct 2018
Director - Process Chemistry Development
Bristol-Myers Squibb Feb 2011 - Jun 2014
Associate Director
Bristol-Myers Squibb Jul 2008 - Feb 2011
Group Leader
Bristol-Myers Squibb Jun 2005 - Jun 2008
Senior Research Investigator Ii
Education:
Princeton University 1994 - 1999
Doctorates, Doctor of Philosophy, Chemical Engineering, Philosophy National Taiwan University 1992
Master of Science, Masters, Bachelors, Bachelor of Science, Chemical Engineering
Skills:
Pharmaceutical Industry
Drug Development
Technology Transfer
Quality By Design
Gmp
Drug Delivery
Formulation
Drug Discovery
R&D
Biopharmaceuticals
Clinical Development
Validation
Glp
Hplc
Pharmaceutics
Organic Chemistry
Biotechnology
Ind
Analytical Chemistry
Fda
Organic Synthesis
Chromatography
Research and Development
Cmc
Project Management
21 Cfr Part 11
Change Control
Strategic Planning
Medicinal Chemistry
Purification
Lc Ms
Sop
Regulatory Submissions
Regulatory Affairs
Pharmacokinetics
V&V
Oncology
Cro
Dissolution
Clinical Trials
Lims
Pharmaceutical Research
Standard Operating Procedure
Languages:
English

Publications

Us Patents

Method Of Preparation Of Azaindole Derivatives

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US Patent:
7598380, Oct 6, 2009
Filed:
Jul 25, 2006
Appl. No.:
11/492750
Inventors:
Wansheng Liu - Edison NJ, US
Sunil S. Patel - Edison NJ, US
Nicolas Cuniere - Belle Mead NJ, US
Yvonne Lear - Candiac, CA
Prashant P. Deshpande - Princeton NJ, US
Jeffrey N. Simon - Lawrenceville NJ, US
Chiajen Lai - Kendall Park NJ, US
Annie J. Pullockaran - Pennington NJ, US
Nachimuthu Soundararajan - Kendall Park NJ, US
Jeffrey T. Bien - Princeton NJ, US
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
C07D 487/04
C07D 213/69
C07D 213/73
US Classification:
544362, 546296, 546311
Abstract:
A method of preparing azaindole compounds for antiviral use having the formula.

Process For Preparing Triazole Substituted Azaindoleoxoacetic Piperazine Derivatives And Novel Salt Forms Produced Therein

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US Patent:
7601715, Oct 13, 2009
Filed:
Jun 19, 2006
Appl. No.:
11/455338
Inventors:
Nachimuthu Soundararajan - Kendall Park NJ, US
Yuping Qiu - Glastonbury CT, US
Wenhao Hu - Princeton NJ, US
David R. Kronenthal - Yardley PA, US
Pierre Sirard - St. Jean sur Richelieu, CA
Jean Lajeunesse - Candiac, CA
Robert Droghini - Candiac, CA
Ramakrishnan Chidambaram - Pennington NJ, US
Xinhua Qian - Flemington NJ, US
Kenneth J. Natalie - Flemington NJ, US
Shawn K. Pack - Plainsboro NJ, US
Nathan Reising - Evansville IN, US
Erqing Tang - Somerset NJ, US
Michael G. Fakes - Belle Mead NJ, US
Qi Gao - Wallingford CT, US
Feng Qian - Hillsborough NJ, US
Blisse J. Vakkalagadda - North Brunswick NJ, US
Chiajen Lai - Kendall Park NJ, US
Shan-Ming Kuang - Florence SC, US
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
A01N 43/58
A61K 31/50
A61K 31/497
C07D 239/00
C07D 239/02
C07D 241/00
C07D 241/02
C07D 295/00
US Classification:
514247, 51425212, 544242, 544336, 544358
Abstract:
A process is provided for preparing triazole substituted azaindoleoxoacetic piperazine derivative. Novel intermediates produced in the above process, and novel N-1 and amorphous forms of a 1,2,3-triazole substituted azaindoloxoacetic piperazine derivatives and processes for producing such novel forms are also provided.

Process For The Preparation Of [(1R), 2S]-2-Aminopropionic Acid 2-[4-(4-Fluoro-2-Methyl-1H-Indol-5-Yloxy)-5-Methylpyrrolo[2, 1-F][1,2,4]Triazin-6-Yloxy]-1-Methylethyl Ester

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US Patent:
7671199, Mar 2, 2010
Filed:
Apr 20, 2007
Appl. No.:
11/737787
Inventors:
Gerard A. Crispino - Lawrenceville NJ, US
Mourad Hamedi - Eatontown NJ, US
Thomas L. LaPorte - Kendall Park NJ, US
John E. Thornton - Newtown PA, US
Jaan A. Pesti - Yardley PA, US
Zhongmin Xu - Princeton NJ, US
Paul C. Lobben - Lawrenceville NJ, US
David K. Leahy - Hightstown NJ, US
Jale Muslehiddinoglu - Hightstown NJ, US
Chiajen Lai - Kendall Park NJ, US
Lori Ann Spangler - Churchville PA, US
Robert P. Discordia - Pennington NJ, US
Francis S. Gibson - Pennington NJ, US
Assignee:
Britsol-Myers Squibb Company - Princeton NJ
International Classification:
C07D 487/04
A61K 31/53
A61P 3/10
US Classification:
544183, 514243
Abstract:
The invention relates to an improved process for preparing [(1R), 2S]-2-aminopropionic acid 2-[4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yloxy]-1-methylethyl ester of the formula:Compound I has been shown to be useful for the treatment of certain types of cancer.

Method Of Preparation Of Azaindole Derivatives

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US Patent:
7820820, Oct 26, 2010
Filed:
Aug 24, 2009
Appl. No.:
12/546108
Inventors:
Wansheng Liu - Edison NJ, US
Sunil S. Patel - Edison NJ, US
Nicolas Cuniere - Belle Mead NJ, US
Yvonne Lear - Candiac, CA
Prashant P. Deshpande - Princeton NJ, US
Jeffrey N. Simon - Lawrenceville NJ, US
Chiajen Lai - Kendall Park NJ, US
Annie J. Pullockaran - Pennington NJ, US
Nachimuthu Soundararajan - Kendall Park NJ, US
Jeffrey T. Bien - Princeton NJ, US
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
C07D 487/04
US Classification:
544362, 546296, 546311
Abstract:
A method of preparing azaindole compounds for antiviral use having the formula.

Crystal Structures Of Sglt2 Inhibitors And Processes For Preparing Same

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US Patent:
7919598, Apr 5, 2011
Filed:
Jun 20, 2007
Appl. No.:
11/765481
Inventors:
Jack Z. Gougoutas - Princeton NJ, US
Hildegard Lobinger - Regensburg, DE
Srividya Ramakrishnan - Milltown NJ, US
Prashant P. Deshpande - Princeton NJ, US
Jeffrey T. Bien - Princeton NJ, US
Chiajen Lai - Kendall Park NJ, US
Chenchi Wang - Somerset NJ, US
Peter Riebel - Ruhstorf a.d. Rott, DE
John Anthony Grosso - Princeton Junction NJ, US
Alexandra A. Nirschl - Yardley PA, US
Janak Singh - Lawrenceville NJ, US
John D. DiMarco - East Brunswick NJ, US
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
C07H 7/04
C07H 1/00
A61K 31/70
US Classification:
536 111, 536124, 514 23
Abstract:
The present invention relates to physical crystal structures of a compound of the formula I:.

Methods Of Producing C-Aryl Glucoside Sglt2 Inhibitors

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US Patent:
7932379, Apr 26, 2011
Filed:
Jun 19, 2007
Appl. No.:
11/764839
Inventors:
Prashant P. Deshpande - Princeton NJ, US
Bruce A. Ellsworth - Princeton NJ, US
Janak Singh - Lawrenceville NJ, US
Theodor W. Denzel - Regensburg, DE
Chiajen Lai - Kendall Park NJ, US
Gerard Crispino - Lawrenceville NJ, US
Michael E. Randazzo - East Windsor NJ, US
Jack Z. Gougoutas - Princeton NJ, US
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
C07H 1/00
US Classification:
536124, 536 111, 536 41
Abstract:
Method for the production of C-aryl glucoside SGLT2 inhibitors useful for the treatment of diabetes and related diseases. and intermediates thereof. The C-aryl glucosides may be complexed with amino acid complex forming reagents.

Process For Preparing Triazole Substituted Azaindoleoxoacetic Piperazine Derivatives And Novel Salt Forms Produced Therein

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US Patent:
7968718, Jun 28, 2011
Filed:
Aug 27, 2009
Appl. No.:
12/548809
Inventors:
Nachimuthu Soundararajan - Kendall Park NJ, US
Yuping Qiu - Princeton Junction NJ, US
Wenhao Hu - Princeton NJ, US
David R. Kronenthal - Yardley PA, US
Pierre Sirard - St. Jean sur Richelieu, CA
Jean Lajeunesse - Candiac, CA
Robert Droghini - Candiac, CA
Ramakrishnan Chidambaram - Santa Clara CA, US
Xinhua Qian - Flemington NJ, US
Kenneth J. Natalie - Flemington NJ, US
Shawn K. Pack - Plainsboro NJ, US
Nathan Reising - Evansville IN, US
Erqing Tang - Somerset NJ, US
Michael G. Fakes - Belle Mead NJ, US
Qi Gao - Franklin Park NJ, US
Feng Qian - Hillsborough NJ, US
Blisse J. Vakkalagadda - North Brunswick NJ, US
Chiajen Lai - Kendall Park NJ, US
Shan-Ming Kuang - Florence SC, US
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
C07D 471/02
US Classification:
546113
Abstract:
A process is provided for preparing triazole substituted azaindoleoxoacetic piperazine derivative. Novel intermediates produced in the above process, and novel N-1 and amorphous forms of a 1,2,3-triazole substituted azaindoloxoacetic piperazine derivatives and processes for producing such novel forms are also provided.

Methods Of Producing C-Aryl Glucoside Sglt2 Inhibitors

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US Patent:
7375213, May 20, 2008
Filed:
Dec 23, 2003
Appl. No.:
10/745075
Inventors:
Prashant P. Deshpande - Princeton NJ, US
Bruce A. Ellsworth - Princeton NJ, US
Janak Singh - Lawrenceville NJ, US
Theodor W. Denzel - Regensburg, DE
Chiajen Lai - Kendall Park NJ, US
Gerard Crispino - Lawrenceville NJ, US
Michael E. Randazzo - East Windsor NJ, US
Jack Z. Gougoutas - Princeton NJ, US
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
C07H 15/203
C07H 15/20
C07H 1/00
US Classification:
536124, 536 111, 536 172, 536 173, 536 174, 536 175, 536 184
Abstract:
Method for the production of C-aryl glucoside SGLT2 inhibitors useful for the treatment of diabetes and related diseases. and intermediates thereof. The C-aryl glucosides may be complexed with amino acid complex forming reagents.
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Chiajen J Lai from Livermore, CA, age ~56 Get Report