US Patent:
20120088730, Apr 12, 2012
Inventors:
Kenneth E. Bernstein - Los Angeles CA, US
Chentao Lin - Los Angeles CA, US
Assignee:
CEDARS-SINAI MEDICAL CENTER - Los Angeles CA
International Classification:
A61K 31/662
A61P 29/00
A61K 38/07
A61K 31/675
C12Q 1/37
US Classification:
514 163, 514119, 514 80, 435 24
Abstract:
The present invention relates to the discovery that the two ACE domains can have very different effects on cytokine expression. In one embodiment, the present invention provides a method of regulating and/or treating a condition in a subject by administering a therapeutically effective dosage of site specific ACE inhibitor. In another embodiment, the condition is inflammation and/or immune response.