US Patent:
20210324085, Oct 21, 2021
Inventors:
- Schlieren, CH
Changhua Ji - Livingston NJ, US
Ekkehard Moessner - Kreuzlingen, CH
Pablo Umana - Wollerau, CH
International Classification:
C07K 16/28
C07K 14/56
Abstract:
The present invention generally relates to antibodies specific for asialoglycoprotein receptor (ASGPR) and their use for selectively delivering effector moieties that influence cellular activity. In addition, the present invention relates to polynucleotides encoding such antibodies, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the antibodies of the invention, and to methods of using them in the treatment of disease.