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Carole C Ober

from Chicago, IL
Age ~74
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Also known as:
Carole L Ober, Carole L O Spielfogel, Carol L Ober, Carole L Spielfogel, Carol L O Spielfogel
Phone and address:
1222 49Th St, Chicago, IL 60615
(773) 536-4418
Related to:
Lenny KauffmanFei Hu, 52Samantha M Lutz, 53Shanna L Adams, 46Scott Salkoff, 49
Connected to:
Brigetta M Ober, 56Bryce Ober, 35David OberEugene R Ober, 66Hal Ober, 93Jason T Ober, 53Jon M Ober, 55Maria Ober, 60Mary T Ober, 76Melissa M Ober, 37

Carole Ober Phones & Addresses

  • 1222 49Th St, Chicago, IL 60615 (773) 536-4418
  • 1222 E 49Th St, Chicago, IL 60615 (312) 446-4671

Work

Position: Construction and Extraction Occupations

Education

Degree: High school graduate or higher

Publications

Us Patents

Snp Binding Site For Micrornas In Hla-G

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US Patent:
20090156532, Jun 18, 2009
Filed:
Jan 23, 2007
Appl. No.:
12/160930
Inventors:
Carole Ober - Chicago IL, US
Zheng Tan - Chicago IL, US
Jihua Fan - New York NY, US
Assignee:
THE UNIVERSITY OF CHICAGO - Chicago IL
International Classification:
A61K 31/7105
C12Q 1/68
US Classification:
514 44, 435 6
Abstract:
Analysis of microRNA interference with HLA-G expression identified the HLA-G 3′UTR SNP+3142G/C that disrupts a target for microRNA 148 (miR148) and is associated with asthma. The polymorphism is associated with protection from (or susceptibility to) moderate to severe viral infection in the first 3 years of life and asthma by age 6, with an interaction with mother's affection status (asthma). A SNP in the 3′-Untranslated Region (UTR) of HLA-G influences the targeting of 3 micro(mi)RNAs to the gene. Allele-specific targeting of these miRNAs accounts, at least in part, for the association between HLA-G and the risk of asthma.

Variation In The Chi3L1 Gene Influences Serum Ykl-40 Levels, Asthma Risk And Lung Function

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US Patent:
20110177963, Jul 21, 2011
Filed:
Nov 26, 2008
Appl. No.:
12/744987
Inventors:
Geoffrey L. Chupp - Madison CT, US
Jack A. Elias - Woodbridge CT, US
Carole Ober - Chicago IL, US
International Classification:
C40B 30/04
C12Q 1/68
G01N 33/559
G01N 33/53
US Classification:
506 9, 435 61, 435 612, 435 611, 436515, 435 792
Abstract:
The present invention is based on the discovery that a single nucleotide polymorphism (SNP) present the chitinase 3-like 1 gene (CHI3L1) encoding YKL-40 or a regulatory domain of the CHI3L1 gene, is associated with elevated YKL-40 levels, as well as an increased risk for developing a lung disorder, including asthma, bronchial hyperresponsivity, and/or reduced lung function.

Use Of Hla-G Genotyping In Immune-Mediated Conditions

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US Patent:
20050287556, Dec 29, 2005
Filed:
May 6, 2005
Appl. No.:
11/123788
Inventors:
Carole Ober - Chicago IL, US
Dan Nicolae - Chicago IL, US
International Classification:
C12Q001/68
US Classification:
435006000
Abstract:
Assays, including those available in kits, are used to obtain HLA-G genotypes. Kits provide reagents and devices to type biological samples for HLA-G through use of SNPs. Genotypes are predictors of risk.
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Carole C Ober from Chicago, IL, age ~74 Get Report