Bruce W Mccaul

55007686, Mar 19, 1996

Apr 16, 1993

8/048611

David F. Doggett - Sunnyvale CA
Bruce W. McCaul - Palo Alto CA

G02B 300
G02B 702

359652

A laser diode lens assembly wherein a lens or lens assembly is immovably adhered to a housing of a laser diode package. The laser diode package may be a metal can style package having a substantially transparent window portion through which laser radiation is emitted when a laser diode inside the housing is supplied with current. The lens or lens assembly may be immovably fixed to an outer surface of this window so that a central axis of a beam of laser radiation emerging from the lens or lens assembly has a desired spatial relationship with a reference surface of the housing. An adhesive such as an epoxy adhesive which is cured under exposure to ultraviolet radiation may be used to freeze the lens or lens assembly in place to the window when the lens is correctly positioned.

54480710, Sep 5, 1995

Apr 16, 1993

8/049474

Bruce W. McCaul - Palo Alto CA
David E. Doggett - Sunnyvale CA
Eric K. Thorson - Snohomish WA

G01J 342

250343

A spectroscopy device comprises a laser diode/lens assembly driven by a periodic stepped laser diode drive current. Each period of the stepped laser diode drive current has a plurality of constant current intervals: a left baseline interval, a left skirt interval, a peak interval, a right skirt interval, and a right baseline interval. The left and right skirt constant current intervals are used to lock the laser radiation emitted from the laser diode onto a preselected absorption line. The left and right baseline constant current intervals are used to subtract baseline absorption measurements from peak constant current interval absorption measurements. A high frequency common mode noise rejection circuit rejects noise common to a monitor radiation detector and a radiation detector which detects radiation passing through a sample cell. A serial line locking cell is provided to allow locking when little or no absorbing material is present in the sample cell. A heated sample cell is provided to allow for the measurement of oxygen concentration in human breath.

61506613, Nov 21, 2000

Dec 21, 1994

8/363094

Bruce W. McCaul - Palo Alto CA
David E. Doggett - Sunnyvale CA

G01N 2117

250343

An absorption spectroscopy device for determining the concentration of a gas (such as oxygen) in a sample cell includes a neutral density absorber or a quarter wave plate. Laser radiation from a laser diode passes through the neutral density absorber or the quarter wave plate, then passes through the sample cell, and then is incident upon a detector. In some embodiments, the laser diode is driven with a drive current having a stepped periodic waveform.

48822345, Nov 21, 1989

Nov 12, 1986

6/930160

Kevin M. Smith - Davis CA
Bruce W. McCaul - Palo Alto CA

Healux, Inc. - Sunnyvale CA

A61K 3140
C07D43722

514185

Carboxyhydroxyporphin compounds such as hematoporphyrin exhibit instability upon warming. However, if this warming is extended and carried out in solution in the presence of a buffer so as to constitute a moderate temperature heat-treatment, a new composition of matter results which contains as much at 95% or more of an ester-linked oligomeric porphin-based material which is exceedingly storage-stable. This composition has superior activity as a photoimaging and photodynamic therapy agent. This process and the products it produces are disclosed. The oligomer products so formed can be formulated into pharmaceutical compositions for use in neoplastic tissue photoimaging and in photodynamic therapy of neoplastic tissues.

56251890, Apr 29, 1997

Mar 16, 1995

8/407520

Bruce W. McCaul - Palo Alto CA
David E. Doggett - Sunnyvale CA

G01N 2100

250343

The absorption of laser radiation by a gas (such as oxygen and/or carbon dioxide) in human breath is detected on-airway by generating laser radiation using a laser diode, passing the laser radiation through a volume containing human breath multiple times, and detecting the laser radiation which is not absorbed by gases in the volume. To reduce the amount of energy required to control the laser diode, a laser diode is selected which generates laser radiation having a wavelength which is reasonably close to the wavelength of an absorption line of a desired gas when the laser diode is at or near normal body temperature. By passing the laser radiation through the sample gas multiple times, a longer path through the sample gas is provided for absorption thereby allowing the concentration of a gas having weak absorption lines (such as oxygen) to be determined using on-airway absorption detection. A two piece on-airway spectroscopy device is disclosed having a disposable mouthpiece portion and a reusable sensor assembly portion having a laser diode and a photodetector.

54913411, Feb 13, 1996

Apr 15, 1994

8/228964

Bruce W. McCaul - Palo Alto CA
David E. Doggett - Sunnyvale CA
Eric K. Thorson - Snohomish WA

G01J 342

250343

A spectroscopy device comprises a laser diode/lens assembly driven by a periodic stepped laser diode drive current. Each period of the stepped laser diode drive current has a plurality of constant current intervals: a left baseline interval, a left skirt interval, a peak interval, a right skirt interval, and a right baseline interval. The left and right skirt constant current intervals are used to lock the laser radiation emitted during the peak interval onto a preselected absorption line. The left and right skirt intervals are also used to obtain a value indicative of line width. The peak interval is used to obtain a value indicative of peak absorbance. Multiplying the peak and line width values together yields a value indicative of a gas concentration which is substantially independent of foreign gas line-broadening effects.

20150219554, Aug 6, 2015

Jan 31, 2014

14/170558

- Chicago IL, US
Mark J. Holland - Port Orchard WA, US
Scott S. Rhodes - Seattle WA, US
Jennifer D. Klemisch - Seattle WA, US
Jessica C. Pavia - Everett WA, US
Thomas Michael Henry - Burien WA, US
Clay J. Anderson - Seattle WA, US
Bruce W. McCaul - Palo Alto CA, US
Thomas Mac Winsemius - Soquel CA, US
Eric K. Thorson - Port Townsend WA, US

The Boeing Company - Chicago IL

G01N 21/39
B64D 37/32
B64D 37/02

An oxygen analysis system (OAS) for measuring, monitoring and recording oxygen concentration in aircraft fuel tanks. The OAS has a rack support structure installed in an aircraft cabin with a plurality of oxygen analyzer devices mounted in the rack support structure. Each oxygen analyzer device has an oxygen sensor to measure oxygen concentration in gas samples continuously drawn from sample locations in aircraft fuel tanks and at an aircraft NGS ASM exit. The OAS further has a plurality of valves, a supply of calibration gases, a supply of purge and operating gases, and a power distribution assembly, all coupled to the rack support structure. The OAS further has a transport tubing assembly, a plurality of fuel tank gas sampling ports, an NGS ASM exit gas sampling port, a drain manifold assembly, and a data acquisition and recording system having a user interface software to monitor and control the OAS.