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Boris Gor Gorbovitski

from Setauket, NY
Age ~68

Boris Gorbovitski Phones & Addresses

  • Setauket, NY
  • Stony Brook, NY
  • 31 Gaul Rd S, Setauket, NY 11733

Resumes

Resumes

Boris Gorbovitski Photo 1

President

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Location:
East Setauket, NY
Industry:
Biotechnology
Work:

President
Boris Gorbovitski Photo 2

President

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Location:
29 Sycamore Cir, Stony Brook, NY 11790
Industry:
Biotechnology
Work:
Biophotonics corp
President

Publications

Us Patents

Single Photon Spectrometer

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US Patent:
8582098, Nov 12, 2013
Filed:
Oct 24, 2008
Appl. No.:
12/734365
Inventors:
Andriy Tsupryk - Coram NY, US
Ivan Tovkach - Centereach NY, US
Dmitriy Gavrilov - Setauket NY, US
Vera Gorfinkel - Brook NY, US
Boris Gorbovitski - Stony Brook NY, US
Dmytro Gudkov - Stony Brook NY, US
Tetyana Gudkova - Coram NY, US
Assignee:
The Research Foundation of State University of New York - Albany NY
International Classification:
G01J 3/42
G01J 1/42
US Classification:
356317, 356320, 356222
Abstract:
A fiberized single photon sensitive spectrometer based on a 32-channel PMT sensor is highly sensitive with broad detection dynamic range. The spectrometer enables accurate and high speed detection, identification and analysis of biological samples labeled with multiple fluorescent markers, such as compositions of multi-color fluorescence signals or radiation emitted by multiple fluorescence dyes. A fiberized optical input of the spectrometer allows an easy and efficient coupling to any measurement system based on fiber collection of the analyzed fluorescence. The spectrometer provides highly accurate DNA sequencing. A 32 channel PMT single photon detector has a detection dynamic range of more than 20 bits and has a frame rate of about 3300 frames per second. The dynamic range of the detector's pixels reaches 10photocounts per second.

System And Method For Cross-Talk Cancellation In A Multilane Fluorescence Detector

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US Patent:
20070194249, Aug 23, 2007
Filed:
Jan 25, 2007
Appl. No.:
11/627146
Inventors:
Dmitri Gavrilov - Port Jefferson Station NY, US
Boris Gorbovitski - Stony Brook NY, US
Vera Gorfinkel - Stony Brook NY, US
Georgiy Gudkov - Centereach NY, US
International Classification:
G01T 1/10
G01J 1/58
F21V 9/16
US Classification:
250459100, 250458100
Abstract:
The present invention is directed to a system and method for cross-talk cancellation for multi-lane fluorescence detectors. The invention may be implemented in accordance with a variety of systems, including systems for multi-capillary electrophoresis. The present invention is based on a special calibration procedure for determination of a channel cross-talk matrix and enables an accurate separation of the fluorescence emitted from individual capillary lanes. The proposed method for cross-talk calibration and removal is very useful for design and development of multi-lane single photon counting detection systems.

Methods And Devices For Detection And Identification Of Encoded Beads And Biological Molecules

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US Patent:
20090203148, Aug 13, 2009
Filed:
Jan 19, 2007
Appl. No.:
12/087812
Inventors:
Vera Gorfinkel - Stony Brook NY, US
Boris Gorbovitski - Stony Brook NY, US
Michael Gorbovitski - Stony Brook NY, US
International Classification:
G01N 33/50
C09K 11/06
C09K 11/02
B01D 57/02
G01N 21/64
US Classification:
436 94, 25230116, 25230135, 204450, 2504612, 977774
Abstract:
The invention relates to methods and devices used in the sequencing, separation, detection, and identification of objects and biological molecules. In preferred embodiments, the invention relates to a DNA sequencing system based on cyclic sequencing by synthesis which is performed on beads in three-dimensional vessels and detected using monolithic multicapillary arrays. In other embodiments, the invention relates to a bead comprising two or more luminescent labels coupled to a nucleic acid sequence. In further embodiments, said luminescent labels are quantum dots.

Absolute Pcr Quantification

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US Patent:
20100137152, Jun 3, 2010
Filed:
Oct 12, 2006
Appl. No.:
12/083407
Inventors:
Vera Gorfinkel - Stony Brook NY, US
Boris Gorbovitski - Stony Brook NY, US
International Classification:
C40B 30/04
C40B 30/00
US Classification:
506 9, 506 7
Abstract:
The present application provides methods and devices for absolute quantification of polymerase chain reaction target nucleic acids. In particular, the methods and devices of the present application provide for splitting a nucleic acid sample to be analyzed into small, isolated volumes, conducting the method of polymerase chain reaction (PCR) on said volumes, detecting PCR amplification products, analyzing said detected PCR amplification products, performing absolute quantification of the PCR target and presenting said quantification results.

Massively Parallel 2-Dimensional Capillary Electrophoresis

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US Patent:
20120152742, Jun 21, 2012
Filed:
Jun 22, 2006
Appl. No.:
11/922515
Inventors:
Vera Gorfinkel - Stony Brook NY, US
Evgeni A. Kabotyanski - Stony Brook NY, US
Boris Gorbovitski - Stony Brook NY, US
International Classification:
G01N 33/50
G01N 27/26
US Classification:
204452, 204603
Abstract:
This invention discloses a highly efficient method, system and apparatus for nucleic acid analysis, including sequencing (both automated re-sequencing and de-novo sequencing). The system is capable of sequencing DNA sizes ranging from fragments to mammalian size genomes having mouse draft quality at a much reduced cost. The system comprises a massive parallel capillary electrophoretic separation using two-dimensional monolith multi-capillary arrays (2D-MMCA). Sequence identification can be performed using fluorescent or otherwise labeled dideoxynucleotide-terminated DNA extension product generated by gel matrix-, or beads-, or substrate tethered-, or otherwise immobilized colonies of single template molecules. Cost reduction is a significant advantage over currently known methods because of: (i) using massively parallel sub-nanoliter volume reactions; and (ii) employing 2D-MMCAs that increase the throughput of the CE separation and detection by at least two orders of magnitude compared to the commercial high-throughput DNA machines.

Quantum True Random Number Generator

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US Patent:
20180217817, Aug 2, 2018
Filed:
Jan 26, 2018
Appl. No.:
15/881275
Inventors:
- Albany NY, US
Boris GORBOVITSKI - Stony Brook NY, US
Dmytro GUDKOV - Setauket NY, US
International Classification:
G06F 7/58
G01J 1/42
Abstract:
A true random number generator including a light source configured to produce randomly distributed photons, a plurality of detection channels configured to receive the randomly distributed photons produced by the light source, each detection channel including a photon sensor configured to detect a receipt of at least one photon during successive integration time-periods and generate an output signal by assigning a value for each integration time-period based on whether at least one photon was received during each integration time-period, a signal conditioning unit configured to condition the output signal of each of the plurality of detection channels and generate a conditioned output signal for each of the plurality of detection channels, and a signal processing unit configured to combine the conditioned output signals and generate a true random number based on the combination of the conditioned output signals.

Absolute Pcr Quantification

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US Patent:
20150017653, Jan 15, 2015
Filed:
Jul 30, 2014
Appl. No.:
14/446635
Inventors:
- Albany NY, US
Boris Gorbovitski - Port Jefferson Station NY, US
International Classification:
C12Q 1/68
US Classification:
435 612
Abstract:
The present application provides methods and devices for absolute quantification of polymerase chain reaction target nucleic acids. In particular, the methods and devices of the present application provide for splitting a nucleic acid sample to be analyzed into small, isolated volumes, conducting the method of polymerase chain reaction (PCR) on said volumes, detecting PCR amplification products, analyzing said detected PCR amplification products, performing absolute quantification of the PCR target and presenting said quantification results.

Absolute Pcr Quantification

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US Patent:
20150017654, Jan 15, 2015
Filed:
Jul 30, 2014
Appl. No.:
14/446654
Inventors:
- Albany NY, US
Boris Gorbovitski - Port Jefferson Station NY, US
International Classification:
C12Q 1/68
US Classification:
435 612
Abstract:
The present application provides methods and devices for absolute quantification of polymerase chain reaction target nucleic acids. In particular, the methods and devices of the present application provide for splitting a nucleic acid sample to be analyzed into small, isolated volumes, conducting the method of polymerase chain reaction (PCR) on said volumes, detecting PCR amplification products, analyzing said detected PCR amplification products, performing absolute quantification of the PCR target and presenting said quantification results.
Boris Gor Gorbovitski from Setauket, NY, age ~68 Get Report