Search

Bernd Spur Phones & Addresses

  • 118 Wagonwheel Ct, Evesham Township, NJ 08053 (856) 983-4953
  • Marlton, NJ

Publications

Us Patents

Polyunsaturated Fatty Acids Interactions And Oxidative Stress Disorders

View page
US Patent:
8563610, Oct 22, 2013
Filed:
Feb 4, 2011
Appl. No.:
13/021196
Inventors:
Thomas P. Stein - Cherry Hill NJ, US
Bernd W. Spur - Marlton NJ, US
George H. Lambert - Belle Meade NJ, US
Sue X. Ming - Morganville NJ, US
Ana Rodriguez - Marlton NJ, US
Assignee:
Rutgers, The State of New Jersey - New Brunswick NJ
Rowan University - Glassboro NJ
International Classification:
A61K 31/20
US Classification:
514560
Abstract:
This invention relates to the identification and treatment of the effects of products derived from oxidative pathways for polyunsaturated fatty acid (PUFA) metabolism, i. e. , oxidative stress in a patient by monitoring the metabolism of DHA or by administering DHA.

Synthesis Of Resolvins And Intermediates, Compounds Prepared Thereby, And Uses Thereof

View page
US Patent:
20100159540, Jun 24, 2010
Filed:
Mar 26, 2008
Appl. No.:
12/450422
Inventors:
Ana Rodriguez - Marlton NJ, US
Bernd Spur - Marlton NJ, US
International Classification:
C12P 7/64
C07C 51/367
C07C 59/42
C07D 309/30
US Classification:
435134, 554126, 554219, 549323
Abstract:
Methods are disclosed for the preparation of a new class of lipid mediators known as resolvins, with Resolvin D6 (4,17-dihydroxy-5E,7Z,10Z,13Z,15E,19Z-docosahexaenoic acid) being exemplary. Also disclosed are methods for the efficient synthesis of key intermediates in the preparation of such resolvins, such as isotopically labeled ω-3 fatty acid metabolites, and derivatives and analogs thereof. The invention likewise extends to the intermediates so prepared, and to the resolvins prepared with their use.

Biochemical Markers For Disease States And Genes For Identification Of Biochemical Defects

View page
US Patent:
20110229883, Sep 22, 2011
Filed:
Apr 9, 2008
Appl. No.:
12/735900
Inventors:
Bernd Spur - Marlton NJ, US
Ana Rodriguez - Marlton NJ, US
Peter T. Stein - Cherry Hill NJ, US
George H. Lambert - Belle Mead NJ, US
Sue X. Ming - Morganville NJ, US
William G, Johnson - Short Hills NJ, US
Edward S. Stenroos - New Brunswick NJ, US
International Classification:
C12Q 1/68
US Classification:
435 611
Abstract:
The present invention relates to a system utilizing biochemical markers and genetic markers to diagnose, predict, and/or monitor intervention of a number of diseases and conditions that have unresolved oxidative stress as an important component. The present invention relates generally to markers and assays for diagnosing, predicting, and monitoring disease, particularly disease-relevant oxidative stress and lipid metabolites and mediators. The oxidative stress, lipid metabolite and lipid mediator biochemical and genetic markers may be further combined with other disease associated or disease relevant markers in methods and assays for diagnosis, monitoring, and assessment of disease, particularly of complex diseases with multi-component factors. The system, methods and assays are applicable to various diseases, including autism, asthma, and Alzheimer's disease.

Method For Treating Sepsis Or Septic Shock

View page
US Patent:
20120220658, Aug 30, 2012
Filed:
Oct 21, 2010
Appl. No.:
13/503494
Inventors:
Kingsley Yin - Cherry Hill NJ, US
Ana Rodriguez - Marlton NJ, US
Bernd W. Spur - Marlton NJ, US
Jean Walker - Aston PA, US
Assignee:
University of Medicine and Dentistry of New Jersey - Somerset NJ
International Classification:
A61K 31/202
A61P 31/00
US Classification:
514557
Abstract:
The present invention is a method for treating sepsis or septic shock using Lipoxin A4.
Bernd W Spur from Marlton, NJ, age ~70 Get Report