Barry D Kuban

7074188, Jul 11, 2006

Aug 25, 2003

10/647971

Anuja Nair - Cleveland Heights OH, US
D. Geoffrey Vince - Avon Lake OH, US
Jon D. Klingensmith - Shaker Heights OH, US
Barry D. Kuban - Avon Lake OH, US

The Cleveland Clinic Foundation - Cleveland OH

A61B 8/00
A61B 8/12

600443, 600463, 600467

A system and method is provided for using backscattered data and known parameters to characterize vascular tissue. Specifically, in one embodiment of the present invention, an ultrasonic device is used to acquire RF backscattered data (i. e. , IVUS data) from a blood vessel. The IVUS data is then transmitted to a computing device and used to create an IVUS image. The blood vessel is then cross-sectioned and used to identify its tissue type and to create a corresponding image (i. e. , histology image). A region of interest (ROI), preferably corresponding to the identified tissue type, is then identified on the histology image. The computing device, or more particularly, a characterization application operating thereon, is then adapted to identify a corresponding region on the IVUS image. To accurately match the ROI, however, it may be necessary to warp or morph the histology image to substantially fit the contour of the IVUS image. After the corresponding region is identified, the IVUS data that corresponds to this region is identified.

7181288, Feb 20, 2007

Jun 24, 2003

10/603243

Ali R. Rezai - Bratenahl OH, US
John D. Hall - Mayfield Heights OH, US
Barry D. Kuban - Avon Lake OH, US
Ken Baker - Chesterland OH, US

The Cleveland Clinic Foundation - Cleveland OH

A61N 1/04

607116, 607117, 607118

A device for modulating a volume of neural tissue comprising: a cannula having a proximal end, a distal end, and a lumen extending to at least the distal end, an actuator mechanism at least partially disposed in the lumen of the cannula; a plurality of leads having at least one electrode disposed thereon, the plurality of leads being coupled to the actuator mechanism to reciprocate between a retracted position wherein the plurality of leads are radially constrained within the lumen and an extended position; and a guide provided at the distal end of the cannula to deflect the plurality of leads radially outwardly into the neural tissue when the actuator mechanism is moved to the extended position.

7215802, May 8, 2007

Apr 29, 2004

10/837352

Jon D. Klingensmith - Shaker Heights OH, US
Anuja Nair - Cleveland Heights OH, US
Barry D. Kuban - Avon Lake OH, US
D. Geoffrey Vince - Avon Lake OH, US

The Cleveland Clinic Foundation - Cleveland OH

G06K 9/00

382128, 600483, 600485

A system and method is provided for using the frequency spectrum of a radio frequency (RF) signal backscattered from vascular tissue to identify at least one border (e. g. , tissue interface, etc. ) on a vascular image. Embodiments of the present invention operate in accordance with a data gathering device (e. g. , an intra-vascular ultrasound (IVUS) device, etc. ) electrically connected to a computing device and a transducer via a catheter. The transducer is used to gather radio frequency (RF) data backscattered from vascular tissue. The RF data is then provided to (or acquired by) the computing device via the data-gathering device. In one embodiment of the present invention, the computing device includes (i) at least one data storage device (e. g. , database, memory, etc. ) for storing a plurality of tissue types and parameters related thereto and (ii) at least one application (e. g.

7359554, Apr 15, 2008

Aug 26, 2003

10/649473

Jon D. Klingensmith - Shaker Heights OH, US
D. Geoffrey Vince - Avon Lake OH, US
Anuja Nair - Cleveland Heights OH, US
Barry D. Kuban - Avon Lake OH, US

Cleveland Clinic Foundation - Cleveland OH

G06K 9/48

382199, 382131, 600467, 606108

A system and method is provided for using a first vascular image, or more particularly a plurality of control points located thereon, to identify a border on a second vascular image. Embodiments of the present invention operate in accordance with an intra-vascular ultrasound (IVUS) device and a computing device electrically connected thereto. Specifically, in one embodiment of the present invention, an IVUS console is electrically connected to a computing device and adapted to acquire IVUS data. The IVUS data (or multiple sets thereof) is then provided to (or acquired by) the computing device. In one embodiment of the present invention, the computing device includes a plurality of applications operating thereon—i. e. , a border-detection application, an extrapolation application, and an active-contour application. These applications are used to (i) identify a border and control points on a first IVUS image (i. e.

7463759, Dec 9, 2008

Jun 8, 2006

11/449569

Jon D. Klingensmith - Shaker Heights OH, US
Anuja Nair - Cleveland Heights OH, US
Barry D. Kuban - Avon Lake OH, US
D. Geoffrey Vince - Avon Lake OH, US

The Cleveland Clinic Foundation - Cleveland OH

G06K 9/00
A61B 5/02

382128, 600483, 600485

A system and method use the frequency spectrum of a radio frequency (RF) signal backscattered from vascular tissue to identify at least one border on a vascular image. A data gathering device is connected to a computing device and a transducer via a catheter. RF data generated via the transducer is provided to the computing device via the data-gathering device. The computing device includes: at least one data storage device for storing a plurality of tissue types and parameters related thereto, and at least one application (e. g. , a characterization application, a gradient-border application, a frequency-border application and/or an active-contour application). The characterization application converts the RF data into the frequency domain and identifies a plurality of associate parameters. The identified parameters are compared to the parameters stored in the data storage device to identify the corresponding tissue type and thereafter determine at least one border on a vascular image.

7678064, Mar 16, 2010

Oct 18, 2007

11/874571

Barry D. Kuban - Avon Lake OH, US

The Cleveland Clinic Foundation - Cleveland OH

A61B 19/00

600557

An apparatus for helping to determine tactile sensitivity of a patient includes a housing and a probe supported by the housing and having a probe tip. The probe is adapted for selective longitudinal movement relative to the housing between a first probe position, wherein the probe tip is substantially extended from the housing, and a second probe position, wherein the probe tip is substantially retracted into the housing. A first biasing means is adapted to urge the probe toward the first probe position. A predetermined motive force is selectively exerted between the probe tip and the patient to move the probe from the first probe position to the second probe position. The motive force is indicative of tactile sensitivity of the patient. A method for helping to determine tactile sensitivity of a patient is also described.

7769470, Aug 3, 2010

Dec 20, 2006

11/641860

Ali Rezai - Shaker Heights OH, US
John Hall - Grand Rapids MI, US
Barry D. Kuban - Avon Lake OH, US
Ken Baker - Chesterland OH, US

The Cleveland Clinic Foundation - Cleveland OH

A61N 1/04

607116, 607 45, 607117

A device for modulating a volume of neural tissue comprising: a cannula having a proximal end, a distal end, and a lumen extending to at least the distal end, an actuator mechanism at least partially disposed in the lumen of the cannula; a plurality of leads having at least one electrode disposed thereon, the plurality of leads being coupled to the actuator mechanism to reciprocate between a retracted position wherein the plurality of leads are radially constrained within the lumen and an extended position; and a guide provided at the distal end of the cannula to deflect the plurality of leads radially outwardly into the neural tissue when the actuator mechanism is moved to the extended position.

7874990, Jan 25, 2011

Jan 14, 2004

10/758477

Anuja Nair - Cleveland Heights OH, US
D. Geoffrey Vince - Avon Lake OH, US
Jon D. Klingensmith - Shaker Heights OH, US
Barry D. Kuban - Avon Lake OH, US

The Cleveland Clinic Foundation - Cleveland OH

A61B 8/00

600449, 600436

A system and method is provided for using ultrasound data backscattered from vascular tissue to estimate the transfer function of a catheter (including components attached thereto—e. g. , IVUS console, transducer, etc. ). Specifically, in accordance with a first embodiment of the present invention, a computing device is electrically connected to a catheter and used to acquire RF backscattered data from a vascular structure (e. g. , a blood vessel, etc. ). The backscattered ultrasound data is then used, together with an algorithm, to estimate the transfer function. The transfer function can then be used (at least in a preferred embodiment) to calculate response data for the vascular tissue (i. e. , the tissue component of the backscattered ultrasound data). In a second embodiment of the present invention, an IVUS console is electrically connected to a catheter and a computing device and is used to acquire RF backscattered data from a vascular structure.