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Balabhaskar Prabhakarpandian

from Madison, AL
Age ~50
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Also known as:
Balabhaska Bal Prabhakarpandian
Phone and address:
104 Oriley Ct, Madison, AL 35758
(256) 895-0069
Related to:
Prabhakar PandianBalabhaskar Prabhakarpandia, 50Chandra Palanichamy, 47
Connected to:
Aruna Prabhakaran, 45Arvind Prabhakar, 50Balu Prabhakar, 74Bangalore S Prabhakar, 79Banureka Prabhakaran, 52Devi M Prabhakaran, 39Gokul C Prabhakar, 58Harish Prabhakaran, 48Prakash Prabhakar, 86Praveen B Prabhakar, 45

Balabhaskar Prabhakarpandian Phones & Addresses

  • 104 Oriley Ct, Madison, AL 35758 (256) 895-0069
  • 6215 Rime Village Dr, Huntsville, AL 35806 (256) 971-1269
  • 6221 Rime Village Dr, Huntsville, AL 35806 (256) 971-1269
  • 607 Avant Ln, Memphis, TN 38105 (901) 525-1017

Publications

Us Patents

Synthetic Microfluidic Microvasculature Network

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US Patent:
7725267, May 25, 2010
Filed:
Mar 31, 2006
Appl. No.:
11/393715
Inventors:
Balabhaskar Prabhakarpandian - Madison AL, US
Shivshankar Sundaram - Madison AL, US
Kapil Pant - Huntsville AL, US
Assignee:
CFD Research Corporation - Huntsville AL
International Classification:
G01N 33/48
US Classification:
702 19
Abstract:
The present invention is a synthetic microfluidic microvasculature network and associated methods. The synthetic microfluidic microvasculature network mimics the structure, fluid flow characteristics, and physiological behavior of physiological microvasculature networks. Computational methods for simulating flow and particle adherence in synthetic and physiological microvascular systems and methods for determining parameters influencing particle adhesion and drug delivery are also described. The invention has many uses including the optimization of drug delivery and microvascular treatments and in describing disease mechanisms that affect the microvasculature such as inflammation, diabetes and hypertension.

Synthetic Microfluidic Microvasculature Network

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US Patent:
8175814, May 8, 2012
Filed:
Apr 22, 2009
Appl. No.:
12/428134
Inventors:
Balabhaskar Prabhakarpandian - Madison AL, US
Shivshankar Sundaram - Madison AL, US
Kapil Pant - Huntsville AL, US
Assignee:
CFD Research Corporation - Huntsville AL
International Classification:
G01N 33/48
US Classification:
702 19
Abstract:
A synthetic microfluidic microvasculature network and associated methods mimic the structure, fluid flow characteristics, and physiological behavior of physiological microvasculature networks. Computational methods for simulating flow and particle adherence in synthetic and physiological microvascular systems and methods for determining parameters influencing particle adhesion and drug delivery are described with applications in the optimization of drug delivery and microvascular treatments and in describing disease mechanisms that affect the microvasculature.

Microfluidic Assay For Selection And Optimization Of Drug Delivery Vehicles To Tumors

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US Patent:
8355876, Jan 15, 2013
Filed:
Dec 28, 2009
Appl. No.:
12/648296
Inventors:
Balabhaskar Prabhakarpandian - Madison AL, US
Kapil Pant - Madison AL, US
Shivshankar Sundaram - Tampa FL, US
Assignee:
CFD Research Corporation - Huntsville AL
International Classification:
G01N 33/48
US Classification:
702 19
Abstract:
An apparatus and method for assaying a tumor drug delivery vehicle comprises a synthetic microvascular network of interconnected flow channels in fluid communication through a porous wall with a tissue space containing animal cells and means for quantifying drug delivery from the microvascular network to the animal cells.

Microfluidic Assay For Characterization Of The Leukocyte Adhesion Cascade

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US Patent:
8380443, Feb 19, 2013
Filed:
Nov 4, 2009
Appl. No.:
12/612573
Inventors:
Balabhaskar Prabhakarpandian - Madison AL, US
Kapil Pant - Madison AL, US
Shivshankar Sundaram - Tampa FL, US
Assignee:
CFD Research Corporation - Huntsville AL
International Classification:
G01N 33/48
US Classification:
702 19
Abstract:
An apparatus and method for identifying and screening for agents affecting the leukocyte adhesion cascade (LAC) encompassing rolling, adhesion and migration comprises an optically clear, plastic microfluidic chip comprising flow channels with diameters in the range of 10-500 μm. The flow channels are coated with endothelial cells and at least a portion of the flow channels contains 1-30 μm sized openings, optionally filled with a native or synthetic extracellular matrix, that allow leukocyte migration into one or more tissue spaces.

Synthetic Microfluidic Blood-Brain Barrier

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US Patent:
8417465, Apr 9, 2013
Filed:
Mar 17, 2010
Appl. No.:
12/726140
Inventors:
Balabhaskar Prabhakarpandian - Madison AL, US
Kapil Pant - Madison AL, US
Shivshankar Sundaram - Tampa FL, US
Ketan Harendrakumar Bhatt - Madison AL, US
Assignee:
CFD Research Corporation - Huntsville AL
International Classification:
G01N 33/48
US Classification:
702 19
Abstract:
An apparatus and method for assaying blood-brain barrier properties for drug and drug delivery vehicle screening comprising of a microfluidic apparatus with gaps separating lumen and tissue space enabling formation of tight junctions similar to in vivo conditions using endothelial cells and brain cells.

Microfluidic Biological Extraction Chip

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US Patent:
8435465, May 7, 2013
Filed:
Nov 3, 2008
Appl. No.:
12/263911
Inventors:
Shivshankar Sundaram - Madison AL, US
Balabhaskar Prabhakarpandian - Madison AL, US
Kapil Pant - Huntsville AL, US
Yi Wang - Madison AL, US
Assignee:
CFD Research Corporation - Huntsville AL
International Classification:
A61J 1/06
US Classification:
422554, 422 50, 422500, 422502, 422527, 422534, 422535, 422559, 422243, 422255, 422261, 435243, 435259, 4353061, 4351734, 4351735, 4351736, 4351737, 436 43, 436514
Abstract:
A microfluidic cartridge for isolating biological molecules having a capture chamber containing functionalized solid supports maintained in a fluidized state provides reduced pressure drops and bubble formation during microfluidic extraction. The cartridge may include an electric field lysis chamber and/or a chemical lysis chamber. The electric-field lysis chamber may comprise an electrically insulating structure arranged between two opposing planar electrodes.

Synthetic Microfluidic Microvasculature Networks

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US Patent:
8589083, Nov 19, 2013
Filed:
Dec 21, 2011
Appl. No.:
13/332400
Inventors:
Balabhaskar Prabhakarpandian - Madison AL, US
Shivshankar Sundaram - Tampa FL, US
Kapil Pant - Huntsville AL, US
International Classification:
G01N 33/48
US Classification:
702 19
Abstract:
A synthetic microfluidic microvasculature network and associated methods mimic the structure, fluid flow characteristics, and physiological behavior of physiological microvasculature networks. Computational methods for simulating flow and particle adherence in synthetic and physiological microvascular systems and methods for determining parameters influencing particle adhesion and drug delivery are described with applications in the optimization of drug delivery and microvascular treatments and in describing disease mechanisms that affect the microvasculature.

Spacer For Delivery Of Medications From An Inhaler To Children And Breathing Impaired Patients

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US Patent:
20050172955, Aug 11, 2005
Filed:
Feb 10, 2004
Appl. No.:
10/775465
Inventors:
Shivshankar Sundaram - Madison AL, US
Balabhaskar Prabhakarpandian - Madison AL, US
Vinod Makhijani - Guilford CT, US
Andrzej Przekwas - Huntsville AL, US
International Classification:
A61M011/00
US Classification:
128200230
Abstract:
A spacer for delivering a medication spray from a metered dose inhaler includes a first conical body joined to a second conical body, forming a continuous spray conduit through first and second internal chambers of the respective first and second conical bodies. A mouthpiece is formed in the small diameter (proximal) end of the first conical body. A spray inlet for attachment to an MDI or similar device is formed at the large diameter (distal) end of the second conical body. A plurality of air inlets are placed downstream of the medication inlet proximate to, or in, the large diameter distal end surface of the first conical body. During use, high-pressure recirculation zones are created in the first and second chambers, near the spray inlet and the air inlets, and an air jacket is created along the inner surface of the wall of the first conical body. This forces the medication spray through the spacer into a defined, central airflow path through the spray conduit, minimizing particle deposition by contact with the walls of the spacer.
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Balabhaskar Prabhakarpandian from Madison, AL, age ~50 Get Report