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Avery Posey Phones & Addresses

  • Philadelphia, PA
  • Indian Head, MD
  • 6405 S Carpenter St, Chicago, IL 60621 (773) 371-0695
  • 6104 S Woodlawn Ave #402, Chicago, IL 60637
  • 5125 S Kenwood Ave #606, Chicago, IL 60615 (773) 855-9815
  • Baltimore, MD
  • 126 Woodland Dr, Indian Head, MD 20640 (301) 753-6848

Work

Position: Sales Occupations

Education

Degree: Bachelor's degree or higher

Emails

Resumes

Resumes

Avery Posey Photo 1

Avery Posey

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Location:
20 Davis Dr, Indian Head, MD 20640
Industry:
Telecommunications
Work:
Versatile Business Solutions Feb 2008 - May 2009
Supervisor

Global Service & System Jan 2001 - Jan 2008
Supervisor

Ict Jan 2000 - Jan 2001
Ict Technician

Radian Int'l Jan 1999 - Jan 2000
Supervisor

Envirocontrol S.a. Jan 1991 - Jan 1999
Laborer, Foreman, and Supervisor
Education:
Tennessee State Universitycharles County Community College
Avery Posey Photo 2

Assistant Professor

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Location:
3535 Market St, Philadelphia, PA 19104
Industry:
Higher Education
Work:
University of Pennsylvania School of Medicine
Assistant Professor

Uncf-Merck
Uncf-Merck Postdoctoral Science Research Fellow

University of Chicago Medicine Jun 2005 - Mar 2011
Graduate Researcher

University of Pennsylvania Jun 2005 - Mar 2011
Assistant Professor
Education:
University of Pennsylvania 2011 - 2016
University of Chicago 2005 - 2011
Doctorates, Doctor of Philosophy, Genetics, Biology, Genomics
University of Maryland Baltimore County 2001 - 2005
Bachelors, Bachelor of Science, Molecular Biology, Biology, Bioinformatics, Biochemistry
Skills:
Cell Culture
Molecular Cloning
Molecular Biology
Pcr
Western Blotting
Protein Expression
Cell Biology
Genetics
Fluorescence Microscopy
Rna Isolation
Crispr/Cas9 Gene Editing

Publications

Us Patents

Phosphoglycerate Kinase 1 (Pgk) Promoters And Methods Of Use For Expressing Chimeric Antigen Receptor

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US Patent:
20230052970, Feb 16, 2023
Filed:
Oct 3, 2022
Appl. No.:
17/937488
Inventors:
- Basel, CH
- Philadelphia PA, US
David Glass - Cambridge MA, US
Thomas Huber - Basel, CH
Julia Jascur - Basel, CH
Carl H. June - Merion Station PA, US
Jihyun Lee - Wynnewood PA, US
Joan Mannick - Cambridge MA, US
Michael C. Milone - Cherry Hill NJ, US
Leon Murphy - Cambridge MA, US
Avery D. Posey - Philadelphia PA, US
Huijuan Song - Shanghai, CN
Yongqiang Wang - Shanghai, CN
Lai Wei - Shanghai, CN
Qilong Wu - Brighton MA, US
Qiumei Yang - Shanghai, CN
Jiquan Zhang - Shanghai, CN
International Classification:
C07K 16/28
A61K 35/17
C07K 16/30
C07K 14/705
A61P 35/02
A61P 35/00
A61K 48/00
C07K 14/725
C12N 15/86
Abstract:
The invention provides compositions and methods for treating diseases associated with expression of a tumor antigen as described herein. The invention also relates to nucleic acids comprising a truncated PGK promoter operably linked to a chimeric antigen receptor (CAR) specific to a tumor antigen as described herein, vectors encoding the same, and recombinant T cells comprising the CARs of the present invention. The invention also includes methods of administering a genetically modified T cell expressing a CAR that comprises an antigen binding domain that binds to a tumor antigen as described herein.

Methods And Compositions Comprising A Viral Vector For Expression Of A Transgene And An Effector

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US Patent:
20210032661, Feb 4, 2021
Filed:
Apr 8, 2019
Appl. No.:
17/046253
Inventors:
- Philadelphia PA, US
Anze Smole - Philadelphia PA, US
Avery D. Posey - Philadelphia PA, US
Donald O'Rourke - Wynnewood PA, US
Yibo Yin - Philadelphia PA, US
Carl June - Merion Station PA, US
Philipp Romel - Philadelphia PA, US
International Classification:
C12N 15/86
C07K 14/725
C07K 14/715
A61K 35/17
C07K 16/32
C07K 14/705
C07K 14/54
Abstract:
The present invention relates to compositions and methods comprising a single viral vector comprising both a first polynucleotide comprising a constitutive promoter operably linked to a nucleic acid encoding at least one transgene, wherein one of the at least one transgenes encodes a receptor or receptor subunit, a receptor fusion protein or a fluorescent marker; and a second polynucleotide comprising an inducible promoter operably linked to a nucleic acid encoding an effector. Also provided are engineered cells comprising the viral vector and methods for generating the engineered cells comprising the viral vector. Also provided is site-specific integration of the genetic element into the a gene locus by means of a CRISPR-related system. Further provided are methods for treating a patient having a disease, a disorder or condition associated with expression of an antigen, the method comprising administering to the patient an effective amount of a composition comprising the engineered cell.

Phosphoglycerate Kinase 1 (Pgk) Promoters And Methods Of Use For Expressing Chimeric Antigen Receptor

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US Patent:
20180118834, May 3, 2018
Filed:
Jan 15, 2016
Appl. No.:
15/543688
Inventors:
Jennifer Brogdon - Cambridge MA, US
Hilmar Erhard Ebersbach - Basel, CH
David Glass - Cambridge MA, US
Thomas Huber - Basel, CH
Julia Jascur - Basel, CH
Carl H. June - Merion Station PA, US
Jihyun Lee - Wynnewood PA, US
Joan Mannick - Cambridge MA, US
Michael C. Milone - Cherry Hill NJ, US
Leon Murphy - Cambridge MA, US
Avery D. Posey - Philadelphia PA, US
Huijuan Song - Shanghai, CN
Yongqiang Wang - Shanghai, CN
Lai Wei - Shanghai, CN
Qilong Wu - Brighton MA, US
Qiumei Yang - Shanghai, CN
Jiquan Zhang - Shanghai, CN
- Basel, CH
- Cambridge MA, US
- Shanghai, CN
- Philadelphia PA, US
International Classification:
C07K 16/28
C07K 14/705
C07K 14/725
A61K 35/17
C07K 16/30
A61P 35/00
A61P 35/02
A61K 48/00
C12N 15/86
Abstract:
The invention provides compositions and methods for treating diseases associated with expression of a tumor antigen as described herein. The invention also relates to nucleic acids comprising a truncated PGK promoter operably linked to a chimeric antigen receptor (CAR) specific to a tumor antigen as described herein, vectors encoding the same, and recombinant T cells comprising the CARs of the present invention. The invention also includes methods of administering a genetically modified T cell expressing a CAR that comprises an antigen binding domain that binds to a tumor antigen as described herein.

Subset-Optimized Chimeric Antigen Receptor-Containing T-Cells

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US Patent:
20170209492, Jul 27, 2017
Filed:
Jul 31, 2015
Appl. No.:
15/327794
Inventors:
Carl H. June - Merion Station PA, US
Sonia Guedan Carrio - Philadelphia PA, US
Avery D. Posey - Philadelphia PA, US
John Scholler - Narberth PA, US
- Basel, CH
- Philadelphia PA, US
Assignee:
NOVARTIS AG - Basel
The Trustees of the University of Pennsylvania - Philadelphia PA
International Classification:
A61K 35/17
C07K 14/705
C07K 14/725
C12N 5/0783
C07K 16/28
Abstract:
This disclosure provides, for instance subset-optimized CART cells and related methods. For instance, the disclosure describes methods and compositions of CD4′ and CD8′ T cells that express CARs containing specific combinations of intracellular signaling domains can be used to increase persistence and anti-tumor activity of the infused CAR-expressing T cells for treating a subject having a disease, e.g., a cancer.
Avery D Posey from Philadelphia, PA, age ~41 Get Report