Inventors:
Arthur C. Switchenko - Palo Alto CA
Nurith Kurn - Palo Alto CA
Christian Neukom - Mountain View CA
Marcel Pirio - San Jose CA
Donald E. Berger - San Jose CA
Edwin F. Ullman - Atherton CA
Assignee:
Behringwerke AG - Marburg
International Classification:
C07C30504
Abstract:
Compounds having detergent properties are disclosed. When a modifying reagent is brought into contact with these compounds, the detergent properties are decreased. These compounds are useful, for example, as solubilizing agents for microbial antigens and/or antibodies and for reversibly wetting hydrophobic surfaces. Accordingly, methods are disclosed for increasing the hydrophilic properties of a material, such as a microbial antigen and/or antibody, the methods generally comprising the steps of contacting the material with the compound having detergent properties and a modifiable group, and modifying the compound with a modifying reagent. Kits are also disclosed for use in accordance with this methodology.