Inventors:
Mary Faris - Los Angeles CA, US
Rene S. Hubert - Los Angeles CA, US
Arthur B. Raitano - Los Angeles CA, US
Daniel E. H. Afar - Brisbane CA, US
Elana Levin - Los Angeles CA, US
Pia Challita-Eid - Encino CA, US
Aya Jakobovits - Beverly Hills CA, US
Assignee:
Agensys, Inc. - Santa Monica CA
International Classification:
A61K039/00
A61K039/38
C12Q001/00
C12Q001/68
G01N033/53
US Classification:
4241851, 4241841, 435 4, 435 6, 435 71, 435 721, 435 723, 435 691, 435 701, 435 702, 435 7021, 514 1, 514 2, 514 8, 514 12, 514 42, 514 43, 514 44, 530300, 530350, 530385, 5303871, 5303877, 5303879, 5303881, 536 111, 536 187, 536 234, 536 235
Abstract:
A novel gene (designated 158P1D7) and its encoded protein are described. While 158P1D7 exhibits tissue specific expression in normal adult tissue, it is aberrantly expressed in multiple cancers including set forth in Table 1. Consequently, 158P1D7 provides a diagnostic and/or therapeutic target for cancers. The 158P1D7 gene or fragment thereof, or its encoded protein or a fragment thereof, can be used to elicit an immune response.