Arthur L Lifshey

6544213, Apr 8, 2003

Sep 11, 2000

09/659221

Arthur L. Lifshey - East Brunswick NJ

Merck Co., Inc. - Rahway NJ

A61M 3700

604 89, 604 90

The present invention is directed to a dual compartment, mixing and dispensing device suitable for the containment of two separate pharmaceutical components that mixable, upon breaking of a seal that separates the compartments, to provide an instantly mixed dose of medication. The medication can be administered to a patient through an aperture located at one end of the device. The device is characterized as two compartments connected by a flexible, sealed orifice, wherein the two components are separated. Flexing of the device at the orifice breaks the seal and allows mixing of the components to prepare the dose. Thereafter, an end-portion of the device can be opened for oral administration of the dose.

20050154434, Jul 14, 2005

Mar 6, 2003

10/504830

Adam Simon - Yardley PA, US
Arthur Lifshey - East Brunswick NJ, US
Elena Fattori - Genzano, IT

A61N001/30
A61N001/00
A61N001/05

607116000, 604021000

A treatment device is provided for applying electrical energy to biological tissue in conjunction with injecting a composition that advantageously diffuses through the tissue. An injector such as a syringe has a reservoir for the treatment composition and injection cannula. The cannula can function as an electrode, and one or more additional electrodes are provided as opposed electrodes. The electrodes can each have tissue penetrating needles, or one or more of the electrodes can have a surface bearing conductive contact part. The syringe or other injector and a drive unit that applies electrical power to the electrodes are operable simultaneously or in a sequence, and can be triggered by switches or automatically upon detection of the injection proceeding to a predetermined state. The treatment device preferably uses a disposable syringe received in a carrier and generally is provided with a non-threatening appearance by minimizing tissue penetration and potential high voltage aspects.

54641225, Nov 7, 1995

Jun 24, 1994

8/265351

Arthur L. Lifshey - East Brunswick NJ

Merck & Co., Inc. - Rahway NJ

B65D 4718
B67B 724

222 83

This invention consists of an ophthalmic dispensing tip formed by injection molding, which has a one-piece molded tip to be used with a mating cap, the tip having an internally molded breakaway barrier membrane inside the flow channel, and the cap having a shaped stud fitting inside the tip, so that the final clockwise half-turn of the cap pushes the stud against the barrier and displaces it, thereby creating a restricted path through which the contents are dispensed.

51861623, Feb 16, 1993

Dec 17, 1990

7/628403

Roger J. Talish - Fairfield NJ
Arthur L. Lifshey - East Brunswick NJ

Interpore Orthopaedics, Inc. - West Caldwell NJ

A61B 1756

128 24AA

The invention contemplates an improved body-applicator unit forming a component of an ultrasonic bone-therapy system exemplified by the disclosure of copending patent application Ser. No. 247,105, filed Sep. 14, 1988 now. U. S. Pat. No. 5,003,965. The improvement features transducer suspension from the rest of the applicator unit via a molded sylphon-bellows element of softly compliant elastomeric material, wherein the transducer is a flat disc, retained as the outer closure wall of the elastomeric bellows, in such manner as to be surrounded by a flexible gel-retaining circumferential lip formation of the bellows.

56738226, Oct 7, 1997

Jun 21, 1995

8/464665

Patrice Chalmin - Chatel Guyon, FR
Jean Gazzola - Clermont Ferrand, FR
Arthur Lifshey - East Brunswick NJ

Laboratoires Merck Sharp & Dohme-Chibret - Paris

B67D 506

222183

The present invention provides a device for the dropwise delivery of a fluid (6) contained in a flexible vial (4; 4'), the device comprising a tubular case (1) capable of surrounding the vial (4; 4'), which casing is provided with a bottom portion (2; 7) whose inner surface lies opposite the outer surface of the bottom wall (42; 42') of the vial (4; 4'), the bottom portion (2; 7) of the casing (1) being equipped with a resiliently displaceable tab (3; 8) which can be moved so as to press against the bottom wall (42; 42') of the vial (4; 4') in order to squeeze the vial (4; 4') and drive out a drop (60) of fluid.

52795551, Jan 18, 1994

Aug 24, 1992

7/934831

Arthur L. Lifshey - East Brunswick NJ

Merck & Co., Inc. - Rahway NJ

A61M 3100

604 60

A device for the subcutaneous implantation of a pharmaceutical dosage form is presented. The device includes a cannula which houses the pharmaceutical dosage form and push member, all of which are prepackaged and may be sterilized. The device further includes an actuator comprising a flexible stylet, a trigger and a handle.

60096918, Jan 4, 2000

Feb 25, 1998

9/030417

Arthur L. Lifshey - East Brunswick NJ

Merck & Co., Inc. - Rahway NJ

B65B 728
B65B 5110
B65B 5132

53478

A process of welding plastic vials and closure suitable for sterile filling operations is disclosed. Following a mechanical seal, a heated die is used to fuse the container and closure into a hermetic seal capable of use in the pharmaceutical industry.

53619471, Nov 8, 1994

Mar 8, 1993

8/027966

Arthur L. Lifshey - East Brunswick NJ

Merck & Co., Inc. - Rahway NJ

B65D 3700

222212

A flexible fluid dispensing bottle is provided which conveniently meters out its contents in several small controlled doses. The device is designed to specifically provide multiple extended outlets to facilitate access beneath the fur of an animal ("comb effect") and to better spread treatment. In addition, the device uses a combination of bottle geometry, and internal ribs and cores to control capacity as well as volume displaced during individual pump strokes of the squeeze bottle.