Inventors:
Ling Tong - Warren NJ, US
Brian J. Lavey - New Providence NJ, US
Bandarpalle B. Shankar - Branchburg NJ, US
Seong Heon Kim - Livington NJ, US
Wensheng Yu - Edison NJ, US
Joseph A. Kozlowski - Princeton NJ, US
Michael K. C. Wong - Somerset NJ, US
Lei Chen - Roselle Park NJ, US
Guowei Zhou - Somerset NJ, US
Razia K. Rizvi - Bloomfield NJ, US
Robert Feltz - Washington PA, US
Aneta Maria Kosinski - South Amboy NJ, US
De-Yi Yang - Morris Plains NJ, US
Chaoyang Dai - Acton MA, US
Luke Fire - Cambridge MA, US
Vinay Girijavallabhan - Denville NJ, US
Dansu Li - Reading MA, US
Janeta Popovici-Muller - Waltham MA, US
Judson E. Richard - Kittery ME, US
Kristin E. Rosner - Watertown MA, US
M. Arshad Siddiqui - Newton MA, US
Liping Yang - Arlington MA, US
International Classification:
A61K 31/4166
A61K 31/4178
A61K 31/4439
A61K 31/454
A61K 31/506
C07D 233/76
C07D 213/24
US Classification:
514302, 544333, 546115, 546193, 5483111, 514269, 514317, 514386
Abstract:
This invention relates to compounds of the Formula (I): (Chemical formula should be inserted here as it appears on abstract in paper form) (I) or a pharmaceutically acceptable salt thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF- or combinations thereof.