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Andrei G Kutateladze

from Denver, CO
Age ~64

Andrei Kutateladze Phones & Addresses

  • 8100 E Union Ave UNIT 1906, Denver, CO 80237 (303) 770-2514
  • 3463 Euclid Ave, Centennial, CO 80121
  • Silverthorne, CO
  • Fitchburg, WI

Business Records

Name / Title
Company / Classification
Phones & Addresses
Andrei Kutateladze
Dean
University of Denver
Higher Education · College/University · University · Graduate Tax Program · Preservation Restoration & Treatment of Artifacts & Historic Objects · School/Educational Services · Colleges and Universities · Schools-Universities & College
2199 S University Blvd, Denver, CO 80208
2420 S University Blvd, Denver, CO 80210
2197 S University Blvd, Denver, CO 80210
2101 S University Blvd, Denver, CO 80210
(303) 871-2000, (303) 871-2360, (303) 871-6041, (303) 871-4944

Publications

Us Patents

Photoinduced Signal Amplification Through Externally Sensitized Photofragmentation In Masked Photosensitizers

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US Patent:
20080312092, Dec 18, 2008
Filed:
Jun 30, 2006
Appl. No.:
11/994694
Inventors:
Andrei G. Kutateladze - Centennial CO, US
Alexei Kurchan - Piscataway NJ, US
Rudresha Kottani - Tucson AZ, US
Janaki Majjigapu - Menomonee WI, US
International Classification:
C40B 30/00
C40B 40/00
G01N 21/64
US Classification:
506 7, 506 13, 436172
Abstract:
A method of photochemically amplifying the chemical signal associated with unmasking a photosensitizer and releasing a radical leaving group when a photochemical chain reaction is initiated by a sensitizer attached to a molecule of interest is provided. More specifically, provided is a method of photoinduced amplification comprising: providing a plurality of masked photosensitizers, each masked photosensitizer having a masking group bonded to a photosensitizer through a releasable covalent bond which disrupts the conjugation of the photosensitizer; providing a reaction photosensitizer in releasing proximity to a first masked photosensitizer; exciting the reaction photosensitizer with photoradiation, whereby the reaction photosensitizer induces release of the masking group from the first masked photosensitizer, producing a first unmasked photosensitizer which induces release of the masking group from a second masked photosensitizer in releasing proximity to the first masked photosensitizer, and so on. The release of the masking group from masked photosensitizer continues as long as masked photosensitizers are in releasing proximity to the reaction photosensitizer, or until a side reaction occurs which stops the chain propagation, or until the source of light is turned off.

Method For Encoding And Screening Combinatorial Libraries

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US Patent:
20090247420, Oct 1, 2009
Filed:
Dec 7, 2006
Appl. No.:
12/096928
Inventors:
Andrei G. Kutateladze - Centennial CO, US
Rudresha Kottani - Tucson AZ, US
Roman Valiulin - Denver CO, US
Janaki Majjigapu - Menomonee WI, US
International Classification:
C40B 30/04
C40B 40/04
US Classification:
506 9, 506 15
Abstract:
A method of screening a library comprising: (i) providing either (a) a library comprising more than one copy of different library members, each copy of a different library member attached to a different releasable tag through a releasable covalent bond; where a plurality of tags uniquely encode each library member; or (b) a library comprising one or more copies of a library member attached to a support, with a plurality of tags uniquely encoding each library member; or (c) a library comprising different library members, each different library member attached to a plurality of tags uniquely encoding the different library member; (ii) providing a target compound with tethered sensitizer in specific binding proximity to the library, allowing specific binding of the target compound with tethered sensitizer to a selected library member; (iii) exciting the tethered sensitizer with excitation photoradiation, whereby the releasable tags attached to the selected library member are released; and (iv) detecting the releasable tags.

Photoinduced Signal Amplification Through Externally Sensitized Photofragmentation In Masked Photosensitizers And Photoamplified Fluorescence Turn-Off System

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US Patent:
20110117667, May 19, 2011
Filed:
Aug 20, 2008
Appl. No.:
12/672105
Inventors:
Andrei G. Kutateladze - Centennial CO, US
Alexei Kurchan - Piscataway NJ, US
Rudresha Kottani - Tucson AZ, US
Janaki Majjigapu - Menomonee WI, US
International Classification:
G01N 21/76
C40B 40/00
US Classification:
436172, 506 13
Abstract:
Provided is a photoamplified fluorescence turn-off assay where a masked photosensitizer is mixed with a fluorescent molecule. This mixture is brightly fluorescent because the masked photosensitizer is not capable of quenching the fluorophore. When the photosensitizer is released and amplified, the photosensitizer quenches the emission of fluorophores very efficiently.

Photolabile System With Instantaneous Fluorescence Reporting Function

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US Patent:
20080293153, Nov 27, 2008
Filed:
Jun 30, 2006
Appl. No.:
11/994686
Inventors:
Andrei G. Kutateladze - Centennial CO, US
Alexei Kurchan - Piscataway NJ, US
Rudresha Kottani - Tucson AZ, US
Janaki Majjigapu - Menomonee WI, US
International Classification:
G01N 21/76
US Classification:
436166, 436172
Abstract:
A method of photofragmentation is provided comprising: providing a masked fluorescent molecule having a masking group bonded to a fluorescent molecule through a photolabile covalent bond; exposing the masked fluorescent molecule to cleaving photoradiation, producing an unmasked fluorescent molecule; detecting the fluorescence of the unmasked fluorescent molecule. The photolabile covalent bond disrupts the conjugation of the fluorescent molecule, causing the fluorescence to be masked. When the photolabile covalent bond is broken, the conjugation is restored, resulting in an increase in fluorescence of the fluorescent molecule as compared to the masked fluorescent molecule.

Isbn (Books And Publications)

Computational Methods In Photochemistry

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Author

Andrei G. Kutateladze

ISBN #

0824753453

Andrei G Kutateladze from Denver, CO, age ~64 Get Report