Alita Lyons Phones & Addresses
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4805 Alt 19 APT 615, Palm Harbor, FL 34683
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Saltaire, NY
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120 W 86Th St #12D, New York, NY 10024 (646) 678-3906
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457 W 57Th St #507, New York, NY 10019
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210 E 25Th St #3RW, New York, NY 10010
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20 84Th St, New York, NY 10024 (212) 580-9577 (212) 799-9592
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524 E 83Rd St #5W, New York, NY 10028 (212) 717-6098
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Santa Fe, NM
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Seattle, WA
Business Records
Name / Title
Company / Classification
Phones & Addresses
Principal
Wont Kill You Cosmetics
Ret Misc Merchandise
Ret Misc Merchandise
20 W 84 St, New York, NY 10024
Publications
Us Patents
Antiviral Compositions And Methods For Identification And Use
View pageUS Patent:
20030143247, Jul 31, 2003
Filed:
Jan 30, 2003
Appl. No.:
10/355455
Inventors:
Hugh Robertson - New York NY, US
Alita Lyons - New York NY, US
Alita Lyons - New York NY, US
International Classification:
C12Q001/68
C12P019/34
A61K039/12
C12N007/00
C12N007/01
C07K002/00
C07K004/00
C07K005/00
C07K007/00
C07K014/00
C07K016/00
C07K017/00
A61K038/00
C12P019/34
A61K039/12
C12N007/00
C12N007/01
C07K002/00
C07K004/00
C07K005/00
C07K007/00
C07K014/00
C07K016/00
C07K017/00
A61K038/00
US Classification:
424/204100, 424/186100, 435/006000, 435/235100, 530/300000, 435/091100
Abstract:
A defined target for hepatitis and picornaviruses, and other viruses which utilize binding of the ribosomes to the internal ribosome entry site (“IRES”) of eukaryotic cells for viral protein translation, has been identified. Useful anti-viral compositions are compounds which block binding, physically or sterically, of the eukaryotic ribosome to the IRES to prevent translation of the viral proteins. The inhibitory molecule may bind to any ribosome subunit, initiation factor, or exposed site on the 40 S, 60 S, 48 S complex or 80 S complex in order to alter specificity of binding of the ribosome. The compounds are identified using the screening methods described herein from libraries of known compounds, including antibiotics. These compounds are then formulated for administration to a patient infected with or exposed to the virus.