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Alexander A Gontcharov

from Brooklyn, NY
Age ~70

Alexander Gontcharov Phones & Addresses

  • 2060 19Th St, Brooklyn, NY 11229
  • 3811 Florence Dr, Alexandria, VA 22305 (571) 431-6658
  • 801 15Th St S, Arlington, VA 22202 (703) 412-2671
  • 801 15Th St S APT 822, Arlington, VA 22202

Work

Position: Building and Grounds Cleaning and Maintenance Occupations

Publications

Us Patents

Processes For Preparing Gonadotropin Releasing Hormone Receptor Antagonists

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US Patent:
7714130, May 11, 2010
Filed:
Jun 16, 2005
Appl. No.:
11/154921
Inventors:
Alexander V. Gontcharov - Rivervale NJ, US
Gulnaz Khafizova - West Nyack NY, US
John R. Potoski - West Nyack NY, US
Donna Mary Huryn - Monmouth NJ, US
Assignee:
Wyeth - Madison NJ
International Classification:
C07D 413/00
C07D 417/00
C07D 419/00
US Classification:
544368
Abstract:
Methods of making Gonadotropin Releasing Hormone (“GnRH”) (also known as Leutinizing Hormone Releasing Hormone) receptor antagonists, comprising reacting a compound having Formula I:.

Asymmetric Synthesis Of Substituted Dihydrobenzofurans

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US Patent:
20060111438, May 25, 2006
Filed:
Oct 21, 2005
Appl. No.:
11/255645
Inventors:
Alexander Gontcharov - Rivervale NJ, US
Gulnaz Khafizova - West Nyack NY, US
John Potoski - West Nyack NY, US
Qing Yu - Laval, CA
Chia-Cheng Shaw - Montreal, CA
Gary Stack - Ambler PA, US
Dahui Zhou - New Brunswick NJ, US
Assignee:
Wyeth - Madison NJ
International Classification:
A61K 31/343
C07D 307/87
C07F 3/02
US Classification:
514469000, 549467000, 26066500G
Abstract:
The present invention concerns production of a compound of the formula or a pharmaceutically acceptable salt thereof by a process which utilizes the cyclization of a compound of the formula: where Ar, Y, R, R, R, and m are as defined herein.

Process For Preparing Substituted Aryl Cycloalkanol Derivatives

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US Patent:
20070129377, Jun 7, 2007
Filed:
Dec 4, 2006
Appl. No.:
11/566415
Inventors:
Alexander Gontcharov - Rivervale NJ, US
Antonia Nikitenko - Tarrytown NY, US
Jean Schmid - Chester NY, US
John Potoski - West Nyack NY, US
Assignee:
Wyeth - Madison NJ
International Classification:
A61K 31/495
C07D 241/04
US Classification:
514252120, 544400000
Abstract:
Processes are disclosed for preparing substituted aryl cycloalkanol derivatives, particularly chiral substituted aryl cycloalkanol derivatives of the general formula:

Chromane And Chromene Derivatives And Uses Thereof

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US Patent:
20080039639, Feb 14, 2008
Filed:
Apr 18, 2007
Appl. No.:
11/787860
Inventors:
Alexander Gontcharov - Rivervale NJ, US
Antonia Nikitenko - Tarrytown NY, US
Panolil Raveendranath - Monroe NY, US
Chia-Cheng Shaw - Ville Saint-Laurent, CA
Bogdan Wilk - New City NY, US
Dahui Zhou - East Brunswick NJ, US
Assignee:
Wyeth - Madison NJ
International Classification:
C07D 311/04
US Classification:
549402000, 549406000, 549407000
Abstract:
Methods of preparing compounds of formula I or pharmaceutically acceptable salts thereof are provided: wherein each of R, R, R, R, x, m, n, and Ar are as defined, and described in classes and subclasses herein, which are agonists or partial agonists of the 2C subtype of brain serotonin receptors. The compounds, and compositions containing the compounds, can be used to treat a variety of central nervous system disorders such as schizophrenia.

Process For The Preparation Of Indolin-2-One Derivatives Useful As Pr Modulators

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US Patent:
20080051585, Feb 28, 2008
Filed:
Aug 15, 2007
Appl. No.:
11/893335
Inventors:
Alexander Gontcharov - Rivervale NJ, US
John Potoski - West Nyack NY, US
Assignee:
Wyeth - Madison NJ
International Classification:
C07D 209/04
US Classification:
548465000, 548512000
Abstract:
Processes for dialkylating indolinones, specifically indolin-2-ones are provided. The processes for dialkylating an indolin-2-one include performing the dialkylation in the presence of at least 2 equivalents of a first base, a second base containing at least 1 equivalent of lithium diisopropylamide, and an alkylating agent. Processes for preparing a compound of the structure are provided, wherein R, R, R, R, R, R, and Rare as defined herein. In one embodiment, a process for preparing 5-(4′-fluoro-2′-oxospiro[cyclopropane-1,3′-indoline]-5′-yl)-1-methyl-1H-pyrrole-2-carbonitrile is provided.

Process For Preparing Indolinone Phenylaminopropanol Derivatives

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US Patent:
20080146645, Jun 19, 2008
Filed:
Aug 22, 2007
Appl. No.:
11/843364
Inventors:
Anita Wai-Yin Chan - Fort Lee NJ, US
Zhixian Ding - Fort Lee NJ, US
Mousumi Ghosh - Elmwood Park NJ, US
Mahmut Levent - Bloomfield NJ, US
Panolil Raveendranath - Monroe NY, US
Jianxin Ren - Nanuet NY, US
Maotang Zhou - Cedar Knolls NJ, US
Asaf Alimardanov - Nanuet NY, US
Alexander V. Gontcharov - Rivervale NJ, US
Antonia A. Nikitenko - Tarrytown NY, US
John R. Potoski - West Nyack NY, US
Girija Raveendranath - Monroe NY, US
Vijay Raveendranath - Albany NY, US
Sanjay Raveendranath - Monroe NY, US
Assignee:
Wyeth - Madison NJ
International Classification:
C07D 209/34
A61K 31/4015
US Classification:
514418, 548486
Abstract:
Processes are disclosed for preparing indolinone phenylaminopropanol derivatives, particularly chiral indolinone phenylaminopropanol derivatives of the general formula:The processes disclosed may be used to prepare, inter alia, 7-fluoro-1-[(S, 2R)-1-(3-fluorophenyl)-2-hydroxy-3-(methylamino)propyl]-3,3-dimethyl-1,3-dihydro-2H-indol-2-one and 7-fluoro-1-[(S, 2R)-1-(3,5-difluorophenyl)-2-hydroxy-3-(methylamino)propyl]-3,3-dimethyl-1,3-dihydro-2H-indol-2-one. Intermediates of the processes are also disclosed.
Alexander A Gontcharov from Brooklyn, NY, age ~70 Get Report