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Alejandro Dorenbaum Dorenbaum

from Mill Valley, CA
Age ~64

Alejandro Dorenbaum Phones & Addresses

  • 120 Stanford Ave, Mill Valley, CA 94941 (415) 381-1625 (415) 389-8309 (415) 389-8507
  • Berkeley, CA
  • Houston, TX
  • San Ysidro, CA
  • San Francisco, CA

Resumes

Resumes

Alejandro Dorenbaum Photo 1

Chief Medical Officer

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Location:
San Francisco, CA
Industry:
Biotechnology
Work:
Reneo Pharmaceutical
Chief Medical Officer

Balance Therapeutics Inc.
Consultant, Clinical Development

Allakos Aug 2014 - Jun 2017
Chief Medical Officer

Shire Jul 2014 - Aug 2015
Senior Clinical Consultant

Lumena Pharmaceuticals 2013 - Jun 2014
Chief Medical Officer
Education:
Baylor College of Medicine 1990 - 2002
The University of Texas Medical School at Houston 1987 - 1990
Universidad Nacional Autónoma De México 1978 - 1986
Doctor of Medicine, Doctorates, Medicine
Skills:
Clinical Development
Clinical Research
Immunology
Biotechnology
Allergy
Clinical
Written
Oral Communications
Metabolic Diseases
Languages:
Hebrew
Spanish
Alejandro Dorenbaum Photo 2

Alejandro Dorenbaum

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Publications

Us Patents

Methods Of Administering Tetrahydrobiopterin, Associated Compositions, And Methods Of Measuring

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US Patent:
7612073, Nov 3, 2009
Filed:
Dec 8, 2008
Appl. No.:
12/329838
Inventors:
Daniel I. Oppenheimer - Castro Valley CA, US
Alejandro Dorenbaum - Mill Valley CA, US
Assignee:
Biomarin Pharmaceutical Inc. - Novato CA
International Classification:
A01N 43/58
A61K 31/50
A01N 43/60
A61K 31/495
US Classification:
514249
Abstract:
The present invention is directed to treatment methods of administering tetrahydrobiopterin, including in oral dosage forms, in intravenous formulations, and with food. Also disclosed herein are biopterin assays for measuring the amount of biopterin and metabolites of biopterin in a sample.

Methods Of Administering Tetrahydrobiopterin, Associated Compositions, And Methods Of Measuring

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US Patent:
7947681, May 24, 2011
Filed:
Oct 12, 2009
Appl. No.:
12/577509
Inventors:
Daniel I. Oppenheimer - Castro Valley CA, US
Alejandro Dorenbaum - Mill Valley CA, US
Augustus Okhamafe - Concord CA, US
Erik Foehr - San Rafael CA, US
Sianna Castillo - San Francisco CA, US
Paul J. Kostel - Santa Rosa CA, US
Assignee:
Biomarin Pharmaceutical Inc. - Novato CA
International Classification:
A01N 43/58
A01N 43/60
A61K 31/50
A61K 31/495
US Classification:
514249
Abstract:
The present invention is directed to treatment methods of administering tetrahydrobiopterin, including in oral dosage forms, in intravenous formulations, and with food. Also disclosed herein are biopterin assays for measuring the amount of biopterin and metabolites of biopterin in a sample.

Methods And Compositions For The Treatment Of Metabolic Disorders

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US Patent:
8067416, Nov 29, 2011
Filed:
Jul 23, 2009
Appl. No.:
12/508209
Inventors:
Daniel I. Oppenheimer - Castro Valley CA, US
Emil D. Kakkis - Novato CA, US
Fredric D. Price - Bedford NY, US
Alejandro Dorenbaum - Mill Valley CA, US
Rudolf Moser - Schaffhausen, CH
Viola Groehn - Dachsen, CH
Thomas Egger - Kempthal, CH
Fritz Blatter - Reinach, CH
Assignee:
Merck Eprova AG - Schaffhausen
Biomarin Pharmaceutical Inc. - Novato CA
International Classification:
A61K 31/495
A61K 31/40
A61K 31/445
A01N 43/54
US Classification:
514249, 514338, 514419, 514258
Abstract:
The present invention is directed to a novel methods and compositions for the therapeutic intervention in hyperphenylalaninemia. More specifically, the specification describes methods and compositions for treating various types of phenylketonurias using compositions comprising BH4. Combination therapies of BH4 and other therapeutic regimens are contemplated.

Methods Of Administering Tetrahydrobiopterin

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US Patent:
RE43797, Nov 6, 2012
Filed:
Nov 18, 2011
Appl. No.:
13/299499
Inventors:
Daniel I. Oppenheimer - Castro Valley CA, US
Alejandro Dorenbaum - Mill Valley CA, US
Augustus O. Okhamafe - Concord CA, US
Assignee:
Biomarin Pharmaceutical Inc. - Novato CA
International Classification:
A01N 43/58
A61K 31/50
A01N 43/60
A61K 31/495
US Classification:
514249
Abstract:
The present invention is directed to treatment methods of administering tetrahydrobiopterin, including in oral dosage forms, in intravenous formulations, and with food. Also disclosed herein are biopterin assays for measuring the amount of biopterin and metabolites of biopterin in a sample.

Methods And Compositions For The Treatment Of Metabolic Disorders

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US Patent:
20060040946, Feb 23, 2006
Filed:
Jun 1, 2005
Appl. No.:
11/143887
Inventors:
Daniel Oppenheimer - Castro Valley CA, US
Emil Kakkis - Novato CA, US
Fredric Price - Bedford NY, US
Alejandro Dorenbaum - Mill Valley CA, US
Assignee:
BioMarin Pharmaceutical Inc. - Novato CA
International Classification:
A61K 31/525
US Classification:
514249000, 514250000
Abstract:
The present invention is directed to a novel methods and compositions for the therapeutic intervention in hyperphenylalaninemia. More specifically, the specification describes methods and compositions for treating various types of phenylketonurias using compositions comprising BH4. Combination therapies of BH4 and other therapeutic regimens are contemplated.

Methods And Compositions For The Treatment Of Metabolic Disorders

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US Patent:
20080090832, Apr 17, 2008
Filed:
Oct 2, 2006
Appl. No.:
11/542310
Inventors:
Daniel Oppenheimer - Castro Valley CA, US
Emil D. Kakkis - Novato CA, US
Fredric D. Price - Bedford NY, US
Alejandro Dorenbaum - Mill Valley CA, US
Assignee:
BIOMARIN PHARMACEUTICAL INC. - Novato CA
International Classification:
A61K 31/5025
A61P 3/00
US Classification:
514249
Abstract:
The present invention is directed to a novel methods and compositions for the therapeutic intervention in hyperphenylalaninemia. More specifically, the specification describes methods and compositions for treating various types of phenylketonurias using compositions comprising BH4. Combination therapies of BH4 and other therapeutic regimens are contemplated.

Methods And Compositions For The Treatment Of Vascular Disease

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US Patent:
20090018136, Jan 15, 2009
Filed:
Jun 5, 2008
Appl. No.:
12/134023
Inventors:
Daniel I. Oppenheimer - Castro Valley CA, US
Emil D. Kakkis - Novato CA, US
Alejandro Dorenbaum - Mill Valley CA, US
International Classification:
A61K 31/4985
A61K 31/53
A61P 7/00
US Classification:
514243, 514249
Abstract:
The present invention is directed to a novel methods and compositions for the therapeutic intervention of vascular complications associated with diabetes, hyperlipidemias, and various cardiovascular disorders including but not limited to recalcitrant hypertension, coronary artery disease, pulmonary arterial hypertension, congestive heart failure, and hemolytic anemias. More specifically, the specification describes methods and compositions for treating such vascular disorders using compositions comprising BH4 and derivative thereof. Combination therapies of BH4 and other therapeutic regimens are contemplated.

Method Of Treating A Metabolic Or Neuropsychiarty Disorder With A Bh4 Derivative Prodrug

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US Patent:
20100009997, Jan 14, 2010
Filed:
Jan 14, 2008
Appl. No.:
12/519806
Inventors:
Daniel I. Oppenheimer - Castro Valley CA, US
Emil D. Kakkis - Novato CA, US
Alejandro Dorenbaum - Mill Valley CA, US
Assignee:
BIOMARIN PHARMACEUTICAL INC. - Novato CA
International Classification:
A61K 31/519
A61P 25/00
US Classification:
514249
Abstract:
Low dose therapeutic methods for use of BH4 derivatives to treat BH4-responsive disorders, such as hyperphenylalanemia and neuropsychiatric diseases, and combination therapies of BH4 derivatives and other therapeutic regimens, are described.
Alejandro Dorenbaum Dorenbaum from Mill Valley, CA, age ~64 Get Report