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Aldo Cagnolini

from West Chester, PA
Age ~56
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Also known as:
Aldo I
Phone and address:
1561 Tanglewood Dr, West Chester, PA 19380
(848) 219-5577
Related to:
Petra L Goelzer, 58
Connected to:
Jennifer L Cagnoli, 33Roger N Cagnon, 62Maria V Cagua, 36Elizabeth M Cague, 39Christopher B Caguiat, 45Michael G Caguiat, 52Mark A Caguioa, 37Michelle L Caguioa, 50Ramil S Caguioa, 46Leonardo M Caguyong, 76

Aldo Cagnolini Phones & Addresses

  • 1561 Tanglewood Dr, West Chester, PA 19380 (848) 219-5577
  • Berwyn, PA
  • Vail, CO
  • 7 Plafsky Dr, Edison, NJ 08817 (732) 572-4025
  • 3606 Quail Ridge Dr, Plainsboro, NJ 08536

Publications

Us Patents

Radiopharmaceutical Formulations

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US Patent:
20050074402, Apr 7, 2005
Filed:
Oct 19, 2001
Appl. No.:
10/399307
Inventors:
Aldo Cagnolini - Edison NJ, US
Karen Linder - Kingston NJ, US
Edmund Marinelli - Lawrenceville NJ, US
International Classification:
A61K051/00
US Classification:
424001650
Abstract:
A method is described for inhibiting the degradation of a diagnostic or radiotherapeutic radiopharmaceutical, especially radiolabeled compounds containing reducible moieties, by including oxidants either as a part of the composition for the preparation of such radiopharmaceuticals, or by adding an oxidant to such compositions immediately after the preparation of such radiopharmaceuticals.

Radiopharmaceutical Formulations

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US Patent:
20060034760, Feb 16, 2006
Filed:
May 5, 2003
Appl. No.:
10/513586
Inventors:
Jiaqing Chen - Plainsboro NJ, US
Karen Linder - Kingston NJ, US
Nannan Wang - Brunswick NJ, US
Aldo Cagnolini - Edison NJ, US
International Classification:
A61K 51/00
US Classification:
424001690
Abstract:
Radiopharmaceutical compounds are disclosed having a radionuclide chelating moiety and a targeting ligand, and optionally a linker. Formulations of compositions useful for making the radiopharmaceutical compounds contain a chelating ligand, a reducing agent, an exchange ligand and a stabilizer.

Chelation Of Metals To Thiol Groups Using In Situ Reduction Of Disulfide-Containing Compounds By Phosphines

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US Patent:
20090062509, Mar 5, 2009
Filed:
Mar 14, 2007
Appl. No.:
12/282766
Inventors:
Aldo Cagnolini - Edison NJ, US
Karen E. Linder - Kingston NJ, US
Hong Helen Fan - PuDong, CN
International Classification:
C07K 7/50
C07K 2/00
C07K 7/06
C07K 1/113
C07K 14/00
US Classification:
530317, 530300, 530328, 530329, 530326, 530345
Abstract:
A method is disclosed for the syntheses of thiol-containing radiopharmaceuticals without the need for purification starting from chelators containing disulfide bonds. This is done by providing a method that reduces disulfide bonds on a precursor molecule or a precursor compound in the presence of phosphine compounds, thus freeing thiols for metal complexation.

Chelation Of Metals To Thiol Groups Using In Situ Reduction Of Disulfide-Containing Compounds By Phosphines

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US Patent:
20120178906, Jul 12, 2012
Filed:
Mar 19, 2012
Appl. No.:
13/423751
Inventors:
Aldo Cagnolini - Edison NJ, US
Karen E. Linder - Kingston NJ, US
Hong (Helen) Fan - Shanghai PuDong, CN
Assignee:
BRACCO IMAGING S.P.A. - Milan
International Classification:
C07K 2/00
US Classification:
530345
Abstract:
A method is disclosed for the syntheses of thiol-containing radiopharmaceuticals without the need for purification starting from chelators containing disulfide bonds. This is done by providing a method that reduces disulfide bonds on a precursor molecule or a precursor compound in the presence of phosphine compounds, thus freeing thiols for metal complexation.
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Aldo Cagnolini from West Chester, PA, age ~56 Get Report