Inventors:
Albertha M. Paul nee Albertha B. Mitchell - Holliston MA
Charles E. Moppett - Mystic CT
Thomas P. Brady - Natick MA
Assignee:
The Dow Chemical Company - Midland MI
International Classification:
C07D25172
Abstract:
Compounds of the. [. formulas. ]. . Iadd. formula. Iaddend. ##STR1## wherein X. sup. - is a lower alkyl carboxylate. [. (I). ]. , a phenylcarboxylate. [. (I). ]. , a lower alkylsulfonate. [. (II). ]. or a phenylsulfonate. [. (II). ]. anion, wherein the phenyl ring may have lower alkyl, lower alkoxy, hydroxyl, amino, nitro, bromo or chloro substitution. The compounds are prepared by reacting the. [. carbinolamine. ]. . Iadd. ring-opened intermediate. Iaddend. prepared by reacting cis-1-(3-chloro-2-propenyl)-3,5,7-triaza-1-azoniatricyclo(3. 3. 1. 1. sup. 3,7) decane chloride with aqueous sodium hydroxide, with a carboxylic or sulfonic acid, as indicated, to form the corresponding 1-cis-(3-chloro-2-propenyl)-3,5,7-triaza-1-azoniatricyclo(3. 3. 1. 1. sup. 3,7) decane carboxylate or sulfonate. These compounds have antimicrobial activity.