Resumes
Resumes
Akiko Iwasaki Phones & Addresses
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1533 Alexander Dr, Guilford, CT 06437 (203) 689-5034
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Fort Knox, KY
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Branford, CT
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114 Fort Hale Rd, East Haven, CT 06512 (203) 466-4077
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265 College St, New Haven, CT 06510 (203) 777-9231
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Bethesda, MD
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1533 Alexander Dr, Guilford, CT 06437 (203) 470-3481
Work
Position:
Sales Occupations
Publications
Amazon
Author
Virginia; Edited with Notes By Fumihiro Wada, Shigeo Fujii; Masami Tokunaga; Akiko Iwasaki Tulley
Binding
Paperback
Publisher
Yamaguchi Shoten
ISBN #
1
Us Patents
Compositions And Methods For Treating Sars-Cov-2 Infection
View pageUS Patent:
20220226363, Jul 21, 2022
Filed:
Mar 30, 2022
Appl. No.:
17/709275
Inventors:
- New Haven CT, US
Akiko Iwasaki - Guilford CT, US
Tianyang Mao - New Haven CT, US
Akiko Iwasaki - Guilford CT, US
Tianyang Mao - New Haven CT, US
International Classification:
A61K 31/7105
A61P 31/14
A61P 31/14
Abstract:
The present disclosure provides small hairpin nucleic acid molecules capable of stimulating interferon production. The nucleic acid molecules of the present disclosure has a double-stranded section of less than 19 base pairs and at least one blunt end. In certain embodiments, the molecule comprises at least one 5′-triphosphate and/or at least one 5′-diphosphate. In certain embodiments, compounds and/or compositions of the disclosure are useful for treating, ameliorating, and/or preventing SARS-CoV-2 viral infection, and/or ameliorating, minimizing, reversing, and/or preventing persistent SARS-CoV-2 viral infection, and/or minimizing or preventing SARS-CoV-2 viral infection-derived mortality and/or lethality, in a subject. In certain embodiments, compounds and/or compositions of the disclosure are useful for treating, ameliorating, and/or preventing SARS-CoV-2 viral infection in a tumor-bearing subject. In certain embodiments, compounds and/or compositions of the disclosure are useful for treating, ameliorating, and/or preventing SARS-CoV-2 viral infection in an immune-compromised and/or immunodeficient subject.
Compositions And Methods For Treating, Ameliorating, And/Or Preventing Viral Infections
View pageUS Patent:
20220175810, Jun 9, 2022
Filed:
Dec 28, 2021
Appl. No.:
17/563686
Inventors:
- New Haven CT, US
Akiko Iwasaki - Guilford CT, US
Tianyang Mao - New Haven CT, US
Akiko Iwasaki - Guilford CT, US
Tianyang Mao - New Haven CT, US
International Classification:
A61K 31/7052
C12N 15/113
A61P 31/14
C12N 15/113
A61P 31/14
Abstract:
The present disclosure provides small hairpin nucleic acid molecules capable of stimulating interferon production. The nucleic acid molecules of the present disclosure has a double-stranded section of less than 19 base pairs and at least one blunt end. In certain embodiments, the molecule comprises a 5′-triphosphate or a 5′-diphosphate. In certain embodiments, compounds and/or compositions of the disclosure are useful for treating, ameliorating, and/or preventing SARS-CoV-2 viral infection, and/or ameliorating, minimizing, reversing, and/or preventing persistent SARS-CoV-2 viral infection, and/or minimizing or preventing SARS-CoV-2 viral infection-derived mortality and/or lethality, in a subject. In certain embodiments, compounds and/or compositions of the disclosure are useful for treating, ameliorating, and/or preventing SARS-CoV-2 viral infection in a tumor-bearing subject. In certain embodiments, compounds and/or compositions of the disclosure are useful for treating, ameliorating, and/or preventing SARS-CoV-2 viral infection in an immune-compromised and/or immunodeficient subject.
A T Cell-Based Immunotherapy For Central Nervous System Viral Infections And Tumors
View pageUS Patent:
20230029362, Jan 26, 2023
Filed:
Dec 4, 2020
Appl. No.:
17/782338
Inventors:
- New Haven CT, US
Akiko Iwasaki - New Haven CT, US
Akiko Iwasaki - New Haven CT, US
International Classification:
A61K 39/00
A61K 39/12
A61K 39/395
C07K 16/10
A61K 39/12
A61K 39/395
C07K 16/10
Abstract:
The present disclosure relates to compositions and methods for treating or preventing a disease or disorder of the brain, spinal cord or central nervous system. It is described herein that an immunogenic composition which induces a CD4 T cell immune response induces permeability of the blood brain barrier, and allows for the access of a therapeutic antibody or agent to the brain, spinal cord or central nervous system.
Cd4 T Cells Provide Antibody Access To Immunoprivileged Tissue
View pageUS Patent:
20210401955, Dec 30, 2021
Filed:
Sep 7, 2021
Appl. No.:
17/467574
Inventors:
- New Haven CT, US
Akiko Iwasaki - New Haven CT, US
Akiko Iwasaki - New Haven CT, US
International Classification:
A61K 39/00
A61K 35/12
A61K 39/02
A61K 39/395
A61K 35/12
A61K 39/02
A61K 39/395
Abstract:
The present disclosure relates to compositions and methods for treating or preventing a disease or disorder of immunoprivileged tissue. It is described herein that an immunogenic composition which induces production of memory CD4 T cells allows for the access of a therapeutic antibody to the immunoprivileged tissue.
Compositions And Methods For Treating, Ameliorating, And/Or Preventing Viral Infections
View pageUS Patent:
20210102209, Apr 8, 2021
Filed:
Dec 9, 2020
Appl. No.:
17/115968
Inventors:
- New Haven CT, US
Andrew Kohlway - Santa Clara CA, US
Dahai Luo - Proteos, SG
David Rawling - San Mateo CA, US
Akiko Iwasaki - Guilford CT, US
Tianyang Mao - New Haven CT, US
Andrew Kohlway - Santa Clara CA, US
Dahai Luo - Proteos, SG
David Rawling - San Mateo CA, US
Akiko Iwasaki - Guilford CT, US
Tianyang Mao - New Haven CT, US
International Classification:
C12N 15/115
A61K 38/21
A61K 31/713
A61K 45/06
A61K 38/21
A61K 31/713
A61K 45/06
Abstract:
The present invention provides a small hairpin nucleic acid molecule that is capable of stimulating interferon production. The nucleic acid molecule of the present invention has a double-stranded section of less than 19 base pairs and at least one blunt end. In certain embodiments, the molecule comprises a 5′-triphosphate or a 5′-diphosphate.
Interferon Production Using Short Rna Duplexes
View pageUS Patent:
20210054380, Feb 25, 2021
Filed:
Aug 25, 2020
Appl. No.:
17/002252
Inventors:
- New Haven CT, US
Andrew Kohlway - Santa Clara CA, US
Dahai Luo - Proteos, SG
David Rawling - San Mateo CA, US
Akiko Iwasaki - Guilford CT, US
Andrew Kohlway - Santa Clara CA, US
Dahai Luo - Proteos, SG
David Rawling - San Mateo CA, US
Akiko Iwasaki - Guilford CT, US
International Classification:
C12N 15/115
A61K 38/21
A61K 31/713
A61K 45/06
A61K 38/21
A61K 31/713
A61K 45/06
Abstract:
The present invention provides a small hairpin nucleic acid molecule that is capable of stimulating interferon production. The nucleic acid molecule of the present invention has a double-stranded section of less than 19 base pairs and at least one blunt end. In certain embodiments, the molecule comprises a 5′ triphosphate or a 5′ diphosphate.
Cd4 T Cells Provide Antibody Access To Immunoprivileged Tissue
View pageUS Patent:
20170326214, Nov 16, 2017
Filed:
May 16, 2017
Appl. No.:
15/596048
Inventors:
- New Haven CT, US
Akiko Iwasaki - New Haven CT, US
Akiko Iwasaki - New Haven CT, US
International Classification:
A61K 39/00
A61K 35/12
A61K 35/12
A61K 39/00
A61K 39/00
A61K 39/00
A61K 35/12
A61K 35/12
A61K 39/00
A61K 39/00
A61K 39/00
Abstract:
The present disclosure relates to compositions and methods for treating or preventing a disease or disorder of immunoprivileged tissue. It is described herein that an immunogenic composition which induces production of memory CD4 T cells allows for the access of a therapeutic antibody to the immunoprivileged tissue.