Search

Aimee Angel Phones & Addresses

  • Atherton, CA
  • Portland, OR
  • 355 Massachusetts Ave, Cambridge, MA 02139
  • 1816 SW Hawthorne Ter, Portland, OR 97201

Publications

Us Patents

Transdermal Transport Device With Suction

View page
US Patent:
7066922, Jun 27, 2006
Filed:
Oct 21, 2002
Appl. No.:
10/278050
Inventors:
Aimee B. Angel - Atherton CA, US
Ian W. Hunter - Lincoln MA, US
Peter Hansen - Mount Eliza Vic, AU
Assignee:
Massachusetts Institute of Technology - Cambridge MA
International Classification:
A61M 31/00
US Classification:
604500, 604 22, 604115, 604264, 604 35, 604176
Abstract:
A transdermal transport device includes a reservoir for holding a formulation of an active principle, and one or more needles. Each needle has a bore through which the formulation is transported between the reservoir and a biological body, and has an end portion that is substantially aligned in a plane parallel to a surface of the biological body when the device is placed on the surface. The device also includes a vacuum generator which creates a suction to draw a portion of the surface beyond the plane of the end portions to enable the end portions to penetrate the portion of the surface as the needles are translated along an axis that is substantially parallel to the plane.

Microneedle Transdermal Transport Device

View page
US Patent:
7364568, Apr 29, 2008
Filed:
Oct 21, 2002
Appl. No.:
10/278049
Inventors:
Aimee B. Angel - Atherton CA, US
Ian W. Hunter - Lincoln MA, US
Assignee:
Massachusetts Institute of Technology - Cambridge MA
International Classification:
A61M 5/00
A61M 5/32
US Classification:
604173, 604174, 604175
Abstract:
A transdermal transport device includes a reservoir for holding a formulation of an active principle, and a needle with a bore extending along the length of the needle from a first end of the needle to a second end of the needle. The second end is substantially aligned to a plane parallel to a body surface of a biological body when the device is placed on the body surface. The device also includes an actuator which pumps the formulation through the bore of the needle between a target area of the body and the reservoir.

Needleless Injector

View page
US Patent:
7425204, Sep 16, 2008
Filed:
Apr 28, 2005
Appl. No.:
11/117082
Inventors:
Aimee B. Angel - Atherton CA, US
Ian W. Hunter - Lincoln MA, US
Assignee:
Massachusetts Institute of Technology - Cambridge MA
International Classification:
A61M 5/30
US Classification:
604 68, 604131, 604134
Abstract:
An injector includes a housing having a chamber for holding a liquid formulation of an active principle to be injected into a biological body and an output port in fluid communication with the chamber through which the liquid formulation is injected. A piston is positioned within the housing, and includes an end portion with substantially the same shape as the chamber. A magnetic force draws the piston and housing together to expel the liquid formulation out of the chamber through the output port.

Microneedle Transport Device

View page
US Patent:
7429258, Sep 30, 2008
Filed:
Sep 9, 2002
Appl. No.:
10/238844
Inventors:
Aimee B. Angel - Atherton CA, US
Ian W. Hunter - Lincoln MA, US
Assignee:
Massachusetts Institute of Technology - Cambridge MA
International Classification:
A61M 5/00
US Classification:
604173, 604140
Abstract:
A transdermal transport device includes a reservoir for holding a formulation of an active principle, and an array of needles which have bores in fluid communication with the reservoir to facilitate transporting the formulation to and from the reservoir through the needles. The device also includes a first actuator which drives the array of needles into the body, and a second actuator which pumps the formulation between the reservoir and the body through the needles. The first actuator is reversible to withdraw the needles from the body.

Detection Of Apex Motion For Monitoring Cardiac Dysfunction

View page
US Patent:
7445605, Nov 4, 2008
Filed:
Mar 30, 2006
Appl. No.:
11/394449
Inventors:
William Ryan Overall - Palo Alto CA, US
Daniel Francis - Los Altos CA, US
Aimee Brigitte Angel - Atherton CA, US
R. Hardwin Mead - Palo Alto CA, US
Assignee:
The Board of Trustees of the Leland Stanford Junior University - Palo Alto CA
International Classification:
A61B 5/103
A61B 5/02
A61N 1/00
US Classification:
600595, 600483, 600527, 600587, 607 17, 607 19
Abstract:
Systems, devices and methods for detecting and monitoring cardiac dysfunction. The devices include motion sensors for detecting signals representative of the total movement of the heart, and of the apex of the heart in particular.

Impedance Sensor

View page
US Patent:
7645263, Jan 12, 2010
Filed:
Oct 21, 2002
Appl. No.:
10/277722
Inventors:
Aimee B. Angel - Atherton CA, US
Ian W. Hunter - Lincoln MA, US
Laura L. Proctor - Cambridge MA, US
James Tangorra - Somerville MA, US
Assignee:
Massachusetts Institute of Technology - Cambridge MA
International Classification:
A61M 1/00
A61M 31/00
A61B 5/05
US Classification:
604116, 604510, 600547
Abstract:
A transdermal transport device includes a reservoir for holding a formulation of an active principle, a needle with a bore through which the formulation is transported between the reservoir and a target area of a biological body, and an impedance sensor. The impedance sensor has an electrode positioned to measure the impedance of a portion of the target area between the needle and the electrode to indicate the depth of penetration of the needle into the target area.

Microneedle Transport Device

View page
US Patent:
7651475, Jan 26, 2010
Filed:
Jan 11, 2008
Appl. No.:
11/972726
Inventors:
Aimee B. Angel - Atherton CA, US
Ian W. Hunter - Lincoln MA, US
Assignee:
Massachusetts Institute of Technology - Cambridge MA
International Classification:
A61M 31/00
US Classification:
604 65, 604151
Abstract:
A transdermal transport device includes a reservoir for holding a formulation of an active principle, and an array of needles which have bores in fluid communication with the reservoir to facilitate transporting the formulation to and from the reservoir through the needles. The device also includes a first actuator which drives the array of needles into the body, and a second actuator which pumps the formulation between the reservoir and the body through the needles. The first actuator is reversible to withdraw the needles from the body.

Microneedle Transdermal Transport Device

View page
US Patent:
8246582, Aug 21, 2012
Filed:
Apr 29, 2008
Appl. No.:
12/150606
Inventors:
Aimee B. Angel - Atherton CA, US
Ian W. Hunter - Lincoln MA, US
Assignee:
Massachusetts Institute of Technology - Cambridge MA
International Classification:
A61M 1/00
US Classification:
604173
Abstract:
A transdermal transport device includes a reservoir for holding a formulation of an active principle, and a needle with a bore extending along the length of the needle from a first end of the needle to a second end of the needle. The second end is substantially aligned to a plane parallel to a body surface of a biological body when the device is placed on the body surface. The device also includes an actuator which pumps the formulation through the bore of the needle between a target area of the body and the reservoir.
Aimee B Angel from Atherton, CA, age ~47 Get Report