Yu C Chen

6406861, Jun 18, 2002

Oct 6, 1999

09/413044

Daniel R. Henderson - Palo Alto CA
Yu Chen - Sunnyvale CA
De Chao Yu - Foster City CA

Cell Genesys, Inc. - Foster City CA

G01N 3353

435 71, 4241401, 4242331, 4241311, 4241591, 4242781, 424 931, 530351, 514885

Methods of reducing pre-existing humoral immunity to a viral immunogenic therapeutic agent such as adenovirus, using immunoapheresis are disclosed. Antibodies specific for the viral immunogenic therapeutic agent are selectively removed from the blood of an individual prior to administration of the viral immunogenic therapeutic agent by reaction extracorporeally with an immunosorbent which specifically binds the antibody. After the antibody is selectively removed from the blood, the blood is reinfused into the patient and the viral immunogenic therapeutic agent is administered. The invention also provides kits and compositions for selective removal of anti-viral antibody.

6548893, Apr 15, 2003

Jul 3, 2001

09/898567

Yu Ju Chen - San Ramon CA
Hui Wu - Milpitas CA

BigBear Networks, Inc. - Milpitas CA

H01L 2312

257704, 257693, 257710, 257728

An apparatus and method for hermetically sealing, EMI shielding integrated circuits for high-speed electronic devices using a combination of microstrip to buried stripline interface for signal transmission from the integrated circuit. The packaging provided comprises a first plurality of microstrips interconnecting the integrated circuit to a plurality of buried striplines exposed on a surface of the main substrate. A ceramic interposer placed over the main substrate âburiesâ a portion of the exposed striplines on the main substrate to thereby insulate these signal paths from a hermetically sealing, and EMI shielding metal lid placed over the integrated circuit. The metal lid and the seal ring brazed over the ceramic interposer thus provide both a hermetic seal and an electric radiation block. A reduction in dispersion due to the buried striplines is also achieved, as well as improving jitter performance.

6697260, Feb 24, 2004

Oct 29, 2001

10/040421

Yu Ju Chen - San Ramon CA
Thomas J. Sleboda - Milpitas CA
Michael Zhong Xuan Wong - Milpitas CA
Hui Wu - Milpitas CA

Big Bear Networks, Inc. - Milpitas CA

H05K 500

361752, 361753, 361736, 361735, 361785, 361803, 361796

An integrated high-speed package comprising a package housing having a housing lip and connector having a center pin abutting along a bottom surface of the housing lip. For signal registration of a first substrate to the signal lead, the substrate is âfloatedâ up to the housing lip, which provides an alignment reference to ensure that the top surface of the first substrate is aligned and in direct registration with the signal lead. In another embodiment, the center pin to substrate registration is provided at a top surface of a housing base. The housing base preferably comprises a first portion of a first height and a second portion of a second height. Accordingly, the housing base can accommodate substrates of different thickness while allowing a top surface of the first and a second substrate to be coplanar to facilitate signal registration there between.

7673143, Mar 2, 2010

Feb 24, 2004

10/786345

William J. Yeager - Menlo Park CA, US
Yu Chen - San Jose CA, US
Brian K. Raymor - Arlington VA, US
Jackson Wong - Menlo Park CA, US

Sun Microsystems, Inc. - Menlo Park CA

H04L 9/32

713175, 713153, 713168

A method for securing a communication between a peer node and an intermediary peer node in a peer-to-peer network comprises the peer node generating a secured communication request to the intermediary peer node. The intermediary peer node authenticates the peer node in response to the secured communication request. The intermediary peer node issues a signed certificate of authority upon successful authentication.

20210149874, May 20, 2021

Jan 30, 2020

16/777858

- San Francisco CA, US
Yvonne Zhou - San Francisco CA, US
Yu Chen - Bellevue WA, US
Shivan Kaul Sahib - Vancouver, CA

salesforce.com, inc. - San Francisco US

G06F 16/23
G06Q 10/10

Implementations retrieve a first event that published to a first source of events responsive to updating, deleting, or inserting a first record in a database object that stores records relating to consent. The first event is processed. Processing the first event includes storing in an attribute of a second event an identifier for a second record that relates to the first record and that is in a second database object that stores records relating to consent. If the first record was inserted or updated, processing the first event includes storing in an attribute of the second event one or more identifiers and respective values of fields of the first record based on attributes of the first event.

20210115133, Apr 22, 2021

Aug 28, 2020

17/005675

- South San Francisco CA, US
Betty Chan Li - Millbrae CA, US
Yu Chen - Foster City CA, US
Taruna Arora - Palo Alto CA, US
Hugo Matern - San Mateo CA, US
Wenyan Shen - Redwood City CA, US

C07K 16/28
A61K 39/00

The present disclosure provides binding proteins, such as antibodies, that bind beta klotho, including human beta klotho, and methods of their use.

20210030857, Feb 4, 2021

Jul 14, 2020

16/928862

- South San Francisco CA, US
Betty Chan Li - Millbrae CA, US
Yu Chen - Foster City CA, US
Taruna Arora - Palo Alto CA, US
Hugo Matern - San Mateo CA, US
Wenyan Shen - Redwood City CA, US

A61K 39/00
C07K 16/28

The present disclosure provides binding proteins, such as antibodies, that bind beta klotho, including human beta klotho, and methods of their use.

20200364224, Nov 19, 2020

May 13, 2019

16/411107

- San Francisco CA, US
Yvonne Zhou - San Francisco CA, US
Yu Chen - Bellevue WA, US
Michael Allan Friedman - Bellevue WA, US
Shivan Kaul Sahib - Vancouver, CA

salesforce.com, inc. - San Francisco US

G06F 16/2453
G06F 16/23
G06F 16/2455

Methods and apparatus for updating a denormalized database object after updating, deleting, or inserting a record in a source database object are described. A first operation on a source database object that involves a record of the source database object being updated, deleted, or inserted is performed. A first part of a corresponding second operation involving a respective record of the denormalized database object being updated, deleted, or inserted is performed. A query result that references an aggregate field of a set of records in the denormalized database object is altered. The altering includes an aggregation operation using values in the query result being performed and altering that part of the query result that includes the aggregate field of the set of records. A second part is optionally performed to complete the corresponding second operation and update the denormalized database object.