Yang Wang

6627883, Sep 30, 2003

Mar 2, 2001

09/798393

Yang Wang - Bedford MA
Melvin A. Park - Billerica MA
Ulrich Geissmann - Arlington MA

Bruker Daltonics Inc. - Billerica MA

B01D 5944

250292, 250287, 250288

The present invention is an improved apparatus and method for mass spectrometry using a dual ion trapping system. In a preferred embodiment of the present invention, three âlinearâ multipoles are combined to create a dual linear ion trap system for trapping, analyzing, fragmenting and transmitting parent and fragment ions to a mass analyzerâpreferably a TOF mass analyzer. The dual ion trap according to the present invention includes two linear ion traps, one positioned before an analytic quadrupole and one after the analytic multipole. Both linear ion traps are multipoles composed of any desired number of rodsâi. e. the traps are quadrupoles, pentapoles, hexapoles, octapoles, etc. Such arrangement enables one to maintain a high âduty cycleâ while avoiding âmemory effectsâ and also reduces the power consumed in operating the analyzing quadrupole.

6906324, Jun 14, 2005

Sep 26, 2003

10/672933

Yang Wang - Bedford MA, US
Melvin A. Park - Billerica MA, US
Ulrich Geissmann - Arlington MA, US

Bruker Daltonics Inc. - Billerica MA

B01D059/44

250292, 250287, 250288

The present invention is an improved apparatus and method for mass spectrometry using a dual ion trapping system. In a preferred embodiment of the present invention, three “linear” multipoles are combined to create a dual linear ion trap system for trapping, analyzing, fragmenting and transmitting parent and fragment ions to a mass analyzer—preferably a TOF mass analyzer. The dual ion trap according to the present invention includes two linear ion traps, one positioned before an analytic quadrupole and one after the analytic multipole. Both linear ion traps are multipoles composed of any desired number of rods—i. e. the traps are quadrupoles, pentapoles, hexapoles, octapoles, etc. Such arrangement enables one to maintain a high “duty cycle” while avoiding “memory effects” and also reduces the power consumed in operating the analyzing quadrupole.

6998610, Feb 14, 2006

Feb 14, 2005

11/057345

Yang Wang - Westford MA, US

H01J 49/40

250290, 250291, 250292, 250294

An ion trap comprises a three-dimensional rotationally symmetric ring electrode and two cap electrodes, the ring electrode is divided, in parallel to its central axis, into a plurality of even number, equal or larger than four, of component electrodes. The component electrodes are electrically isolated from each other, the surfaces of the two cap electrodes face toward the inside of the ion trap. A mechanism is constructed and arranged for switching the ion trap to operate between a three-dimensional quadrupole ion trap mode and a two-dimensional linear ion trap mode.

7019289, Mar 28, 2006

Jan 23, 2004

10/764252

Yang Wang - Westford MA, US

H01J 49/04

250290, 250291, 250292, 250294

An ion trap comprises a three-dimensional, rotationally symmetric ring electrode and two cap electrodes with hyperbolic surfaces facing toward the inside of the ion trap, each of the two cap electrodes being further composed of a first hyperbolic cone electrode and a second disk electrode. The ion trap also includes a RF or periodic circuitry constructed and arranged for applying a RF or periodic voltage to the ring electrode to generate a main quadrupole field, an AC circuitry constructed and arranged for applying an AC voltage to the disk electrodes of said two cap electrodes to generate a dipole field, and a DC circuitry constructed and arranged for applying an DC voltage to the cone electrodes of the two cap electrodes to independently generate an electrically variable electrostatic octopole field in the ion trap. The ion trap is capable to achieve higher mass-resolving power, especially in higher gas pressure or lower vacuum condition. To achieve higher mass-measuring sensitivity, the ion trap can be switched electrically between the three-dimensional trap mode and two-dimensional trap mode by dividing the trap's ring electrode into multiple elements.

7326926, Feb 5, 2008

Jul 6, 2005

11/175535

Yang Wang - Westford MA, US

H01J 49/10

250288, 250423 R, 250424, 250324, 264 22, 422907, 436173

A corona discharge mass spectrometer or an ion mobility spectrometer is provided with a robust corona discharge ionization source. The corona discharge ionization source, which can be operated at atmospheric pressures or at low vacuum, includes a multi-thread electrode and plane electrode. The multiple thread electrode has multiple discharge tips which provide redundancy, and improve ionization stability and the reliability and efficiency of the ionization source.

7329864, Feb 12, 2008

Sep 12, 2005

11/224622

Yang Wang - Westford MA, US

H01J 49/06
H01J 49/42

250288, 250281, 250292

Multiple ionization ion sources and multiple mass analyzers are combined into one mass spectrometer instrument by a six-electrodes ion trap or an array of six-electrodes ion traps. The six-electrodes ion trap can be operated as an independent two-dimensional ion guide or linear ion tap in an arbitrarily selected direction among three orthogonal XYZ directions. The two-dimensional ion guide/linear ion trap can be alternated from one direction to another among the three orthogonal directions electrically. A six-electrodes ion trap generates six equivalent importing and exporting interfaces, each of the interfaces can be used to trap external ions and transfer the trapped ions to any of the other five interfaces. The six-electrodes ion trap provide a mass spectrometer with versatility, multiply functions, high duty-cycles and high sample throughput.

7329866, Feb 12, 2008

Jul 25, 2005

11/188930

Yang Wang - Westford MA, US

B01D 59/44

250290, 250292, 250294

A two-dimensional ion trap comprises a first and second trapping plate located in a first and second terminals of the ion trap device, a set of four predetermined surface-shaped rods located in the center, a set of electrodes located between the set of four predetermined surface-shaped rods, and a control circuitry for applying a predetermined voltage to said first and second trapping plates.

7449686, Nov 11, 2008

Jun 7, 2005

11/146910

Yang Wang - Bedford MA, US
Melvin A. Park - Billerica MA, US
Ulrich Geissmann - Arlington MA, US

Bruker Daltonics, Inc. - Billerica MA

H01J 49/42
H01J 49/06

250292, 250288

The present invention is an improved apparatus and method for mass spectrometry using a dual ion trapping system. In a preferred embodiment of the present invention, three “linear” multipoles are combined to create a dual linear ion trap system for trapping, analyzing, fragmenting and transmitting parent and fragment ions to a mass analyzer—preferably a TOF mass analyzer. The dual ion trap according to the present invention includes two linear ion traps, one positioned before an analytic quadrupole and one after the analytic multipole. Both linear ion traps are multipoles composed of any desired number of rods—i. e. the traps are quadrupoles, pentapoles, hexapoles, octapoles, etc. Such arrangement enables one to maintain a high “duty cycle” while avoiding “memory effects” and also reduces the power consumed in operating the analyzing quadrupole.