Yan N Liu

7004624, Feb 28, 2006

Nov 14, 2003

10/713491

Yan Liu - Monterey Park CA, US

G01K 11/00
G01J 5/00

374162, 374130, 374121

A method and apparatuses for measuring the temperature of a radiating body utilizing the alexandrite effect. The method includes the steps of generating a mathematical relationship between a hue value and temperature for an alexandrite effect filter, receiving radiation from the radiating body, measuring a spectral power distribution of the radiation, calculating the hue value based on the spectral power distribution, and determining the temperature using the mathematical relationship. To implement the method, the apparatuses include an optical probe, a spectral or calorimetric measurement device, and a computer. The apparatuses can measure the temperature of any radiating body with or without spectral lines in the spectral power distribution, and are particularly advantageous to measure high to ultrahigh temperature for radiating bodies with spectral lines, such as plasma, electric arc, and high temperature flames.

7052177, May 30, 2006

Apr 22, 2005

11/112054

Yan Liu - Monterey Park CA, US

G01K 11/00
G01J 5/00

374162, 374130, 374121

A method and apparatuses for measuring the temperature of a radiating body utilizing the alexandrite effect. The method includes the steps of generating a mathematical relationship between a hue value and temperature for an alexandrite effect filter, receiving radiation from the radiating body, measuring a spectral power distribution of the radiation, calculating the hue value based on the spectral power distribution, and determining the temperature using the mathematical relationship. To implement the method, the apparatuses include an optical probe, a spectral or calorimetric measurement device, and a computer. The apparatuses can measure the temperature of any radiating body with or without spectral lines in the spectral power distribution, and are particularly advantageous to measure high to ultrahigh temperature for radiating bodies with spectral lines, such as plasma, electric arc, and high temperature flames.

7378784, May 27, 2008

May 13, 2005

11/129703

Yan Liu - Monterey Park CA, US

H01J 5/16

313110, 313112

An optical filter used for modifying the spectral power distribution of high color temperature lamp to simulate CIE standard daylight illuminant. The optical filter comprising a heat-absorbing glass plate, a heat insulation washer, a longpass glass plate, and one or more spectral modification glass plate in series. The longpass glass plate and the heat absorbing glass plate determine the wavelength range, and the spectral modification glass plate(s) modify the spectral power distribution of the high color temperature halogen lamp. The CIE daylight simulators with the optical filter have very high colorimetric indexes.

7388656, Jun 17, 2008

Dec 30, 2005

11/322431

Yan Liu - Monterey Park CA, US

G01N 21/87

356 30

A method and system, including a computer program product, implementing a color terminology for accurate color grading of gemstones are provided. The method includes generating a reference color to match that of a graded gemstone under the standard viewing environment, processing color data in different color spaces, assigning a color grade to specify the color of the gemstone graded. The reference color can be continuously changed by adjusting the hue, lightness and saturation values. The color grade comprises a color name and one or more corresponding color coordinates and/or one or more corresponding color notations, in the form of Color Name (Color Coordinates). The color name is used for verbal description of the color, and the color coordinate or color notation is for accurate color communication in the jewelry industry.

7652755, Jan 26, 2010

Feb 23, 2007

11/678564

Yan Liu - Monterey Park CA, US

G01N 21/00
G01J 1/04

356 30, 356236, 250228

The present invention discloses an apparatus that comprises a spectrometer, and computer and a dual integrating sphere measurement arrangement comprising a measurement integrating sphere, a sample integrating sphere, a sample platform, a filter, a lens system, a baffle and a light source. The sample integrating sphere encloses a sample to provide a constant environment for simulating the visual color grading environment. The computer controls the spectrometer and provides measurement parameters calculated from physical parameters of the measured sample, including, but not limited to, shape, dimensions, refractive index, intensity of fluorescence and cut grade. The computer then calculates spectral reflectance and colorimetric data, and determines an average color grade by checking a look-up-table that represents the relationship between the CIELAB coordinate and the average color grade. The computer also determines a true color grade based upon the average color grade and the physical parameters, using mathematical analytic algorithms.

20100141929, Jun 10, 2010

Jun 2, 2009

12/477091

YAN Liu - Monterey Park CA, US

G01N 21/55

356 30

The present invention discloses method for color measurement and color grading of faceted gemstones, diamonds and the like. A novel three-step calibration insures an accurate spectral measurement of the sample inside the measurement integrating sphere. Using the method of the present invention, a computer provides measurement parameters calculated from the physical parameters of the measured sample, including, but not limited to, shape, dimensions, refractive index, intensity of fluorescence and cut grade. By means of the present invention, a computer then calculates the spectral reflectance and colorimetric data, and determines an average color grade by checking a look-up-table that represents the relationship between the CIELAB coordinate and the average color grade, and it also determines a true color grade based upon the average color grade and the physical parameters, using mathematical analyses and algorithms.

20210090732, Mar 25, 2021

Apr 27, 2018

16/499152

- Los Angeles CA, US
Peter Kuhn - Los Angeles CA, US
Yan Liu - Los Angeles CA, US
Paymaneh Malihi - Los Angeles CA, US
Sanjay Purushotham - Los Angeles CA, US

G16H 50/20
G06N 3/08
G06N 3/04
G16H 10/60
G16H 50/30
G16H 10/40
G16H 50/70
G16H 40/67

Methods, systems, and apparatus for a method that predicts an individual survival survival time of a patient. The method includes obtaining clinical data associated with health factors of the patient. The method includes obtaining liquid biopsy data associated with one or more attributes of diseased cells within the patient. The method includes predicting or determining a survival time of the patient using a deep learning model based on the clinical data and the liquid biopsy data. The method includes providing or outputting the survival time.

20200270353, Aug 27, 2020

Mar 30, 2020

16/835171

- La Jolla CA, US
Yong ZHANG - Temple City CA, US
Yan LIU - San Diego CA, US
Peter G. SCHULTZ - La Jolla CA, US

C07K 16/28
C07K 14/81
C07K 14/64
C07K 14/605
C07K 14/47
C07K 16/32
C07K 14/61
C07K 14/435
C07K 14/575
C07K 14/535
C07K 14/505
A61K 47/68
A61K 47/65
C07K 14/705
C07K 16/10
A61K 39/395

Disclosed herein are immunoglobulin fusion proteins comprising a first antibody region, a first therapeutic agent, and a first connecting peptide; wherein the first therapeutic agent is attached to the first antibody region by the connecting peptide; and wherein the connecting peptide does not comprise a region having beta strand secondary structure. The connecting peptide may comprise an extender peptide. The extender peptide may have an alpha helical secondary structure. The connecting peptide may comprise a linker peptide. The linker peptide may not comprise any secondary structure. Also disclosed herein are compositions comprising the immunoglobulin fusion proteins and methods for using the immunoglobulin fusion proteins for the treatment or prevention of a disease or condition in a subject.