Vu N Bui

20200261898, Aug 20, 2020

Feb 24, 2020

16/798954

- Santa Monica CA, US
Peter Meinhold - Santa Monica CA, US
Pedro Coelho - Santa Monica CA, US
Vu Bui - Santa Monica CA, US
Levente Ondi - Budapest, HU
Hasan Mehdi - Budapest, HU

Provivi, Inc. - Santa Monica CA

B01J 31/22
C07C 67/293
C07C 6/04
C07C 45/41
C07C 67/343
C07C 67/08
C07C 29/147

In one aspect, the invention provides a method for synthesizing a fatty olefin derivative. The method includes: a) contacting an olefin according to Formula Iwith a metathesis reaction partner according to Formula IIbin the presence of a metathesis catalyst under conditions sufficient to form a metathesis product according to Formula IIIb:andb) converting the metathesis product to the fatty olefin derivative. Each Ris independently selected from H, Calkyl, and Calkenyl; Ris Calkyl; subscript y is an integer ranging from 0 to 17; and subscript z is an integer ranging from 0 to 17. In certain embodiments, the metathesis catalyst is a tungsten catalyst or a molybdenum catalyst. In various embodiments, the fatty olefin derivative is a pheromone. Pheromone compositions and methods of using them are also described.

20200039900, Feb 6, 2020

Aug 16, 2019

16/543384

- Santa Monica CA, US
Vu Bui - Santa Monica CA, US
David Rozzell - Burbank CA, US
Pedro Coelho - Santa Monica CA, US
Arthur Floruti - Santa Monica CA, US
Levente Ondi - Veresegyhaz, HU
Hasan Mehdi - Budapest, HU
Gabor Eros - Budapest, HU

Provivi, Inc. - Santa Monica CA

C07C 6/04
B01J 31/22

Methods for preparation of olefins, including 8- and 11-unsaturated monoenes and polyenes, via transition metathesis-based synthetic routes are described. Metathesis reactions in the methods are catalyzed by transition metal catalysts including tungsten-, molybdenum-, and ruthenium-based catalysts. The olefins include insect pheromones useful in a number of agricultural applications.

20180099268, Apr 12, 2018

Sep 29, 2017

15/721018

- Santa Monica CA, US
Peter Meinhold - Santa Monica CA, US
Pedro Coelho - Santa Monica CA, US
Vu Bui - Santa Monica CA, US
Levente Ondi - Veresegyhaz, HU
Hasan Mehdi - Budapest, HU

Provivi, Inc. - Santa Monica CA

B01J 31/22
C07C 6/04
C07C 29/147
C07C 67/08
C07C 67/293
C07C 67/343
C07C 45/41

In one aspect, the invention provides a method for synthesizing a fatty olefin derivative. The method includes: a) contacting an olefin according to Formula Iwith a metathesis reaction partner according to Formula IIbin the presence of a metathesis catalyst under conditions sufficient to form a metathesis product according to Formula IIIb:and b) converting the metathesis product to the fatty olefin derivative. Each Ris independently selected from H, Calkyl, and Calkenyl; Ris Calkyl; subscript y is an integer ranging from 0 to 17; and subscript z is an integer ranging from 0 to 17. In certain embodiments, the metathesis catalyst is a tungsten catalyst or a molybdenum catalyst. In various embodiments, the fatty olefin derivative is a pheromone. Pheromone compositions and methods of using them are also described.

20170137365, May 18, 2017

Nov 17, 2016

15/354916

- Santa Monica CA, US
PETER MEINHOLD - Santa Monica CA, US
PEDRO COELHO - Santa Monica CA, US
VU BUI - Santa Monica CA, US
LEVENTE ONDI - Veresegyhaz, HU
HASAN MEHDI - Budapest, HU

PROVIVI, INC. - Santa Monica CA

C07C 67/293
B01J 31/22
C07C 69/533

In one aspect, the invention provides a method for synthesizing a fatty olefin derivative. The method includes: a) contacting an olefin according to Formula Iwith a metathesis reaction partner according to Formula IIbin the presence of a metathesis catalyst under conditions sufficient to form a metathesis product according to Formula IIIb:and

20160108436, Apr 21, 2016

Sep 3, 2015

14/845212

- Santa Monica CA, US
Mike M.Y. Chen - Santa Monica CA, US
Peter Meinhold - Santa Monica CA, US
Catherine Mee-Hie Cho - Santa Monica CA, US
Vu Bui - Santa Monica CA, US
Thomas Heel - Santa Monica CA, US

Provivi, Inc. - Santa Monica CA

C12P 7/04
C07C 67/14
C07C 51/235
C07C 45/29

In certain aspects, the present invention provides methods for producing terminally hydroxylated alkenes and alkynes by contacting an unsaturated or saturated hydrocarbon substrate with a hydroxylase enzyme. Exemplary terminal hydroxylases useful for carrying out the methods of the invention exhibit strong selectivity towards one terminal carbon of a hydrocarbon substrate and include, but are not limited to, non-heme diiron alkane monooxygenases, cytochromes P450 (e.g., cytochromes P450 of the CYP52 and CYP153 family), as well as long chain alkane hydroxylases. In some embodiments, the terminally hydroxylated alkene or alkyne is further converted to a terminal alkenal. In certain embodiments, terminally hydroxylated alkenes and alkynes are useful as insect pheromones which modify insect behavior. In other embodiments, terminally hydroxylated alkenes and alkynes are useful intermediates for producing pheromones via acetylation or oxidation of the alcohol moiety.