Inventors:
Daniel Dube - St-Lazare, CA
Michel Gallant - Laval, CA
Erich L. Grimm - Baie d'Urfe, CA
Helene Juteau - Quebec, CA
Sebastien Laliberte - Vaudreuil-Dorion, CA
Tom Yao-Hsiang Wu - Hacienda Heights CA, US
Assignee:
Merck Canada Inc. - Kirkland, Quebec
International Classification:
A61K 31/4545
A61K 31/451
C07D 211/60
US Classification:
514318, 514330, 546194, 546225
Abstract:
The present invention relates to disubstituted piperidinyl renin inhibitor compounds having the structure (Formula I) and their use in treating cardiovascular events and renal insufficiency.