US Patent:
20120129261, May 24, 2012
Inventors:
James Eberwine - Philadelphia PA, US
Tai Kyung Kim - Wynnewood PA, US
Vickas Patel - Berwyn PA, US
International Classification:
C12N 15/85
C12N 5/071
C12N 1/20
C12N 15/63
US Classification:
435455, 435471, 435375, 435377, 4352521, 435366
Abstract:
The present invention includes methods for effecting phenotype conversion in a cell by transfecting the cell with phenotype-converting nucleic acid. Expression of the nucleic acids results in a phenotype conversion in the transfected cell. Preferably the phenotype-converting nucleic acid is a transcriptome, and more preferably an mRNA transcriptome.