Tae Ok Lee

6358567, Mar 19, 2002

Apr 16, 1999

09/293446

Robert S. Glass - Livermore CA
Tae H. Lee - Naperville IL

The Regents of the University of California - Oakland CA

B05D 102

427421, 427316, 427318, 427319, 4273762, 4273763, 4273764, 427427

A dense or porous coating of material is deposited onto a substrate by forcing a colloidal suspension through an ultrasonic nebulizer and spraying a fine mist of particles in a carrier medium onto a sufficiently heated substrate. The spraying rate is essentially matched to the evaporation rate of the carrier liquid from the substrate to produce a coating that is uniformly distributed over the surface of the substrate. Following deposition to a sufficient coating thickness, a single sintering step may be used to produce a dense ceramic coating. Using this method, coatings ranging in thickness from about one to several hundred microns can be obtained. By using a plurality of compounds in the colloidal suspension, coatings of mixed composition can be obtained. By using a plurality of solutions and separate pumps and a single or multiple ultrasonic nebulizer(s), and varying the individual pumping rates and/or the concentrations of the solutions, a coating of mixed and discontinuously graded (e. g. , stepped) or continuously graded layers may be obtained.

6448377, Sep 10, 2002

Sep 27, 2000

09/672239

Brian Kobilka - Palo Alto CA
Tae Weon Lee - Palo Alto CA

The Board of Trustees of the Leland Stanford Junior University - Palo Alto CA

C07K 1700

530350, 435 71

The present invention provides modified G protein -subunits which are characterized by constitutive localization to the plasma membrane; enhanced binding to one or more of the normal receptor binding partners for that -subunit; and efficient binding to and activation of G protein binding partners. The distribution of these modified -subunits, which are âtetheredâ to the plasma membrane, allows the regulation of receptor-G protein coupling, and thus G-protein signaling, in various biological systems.

6846558, Jan 25, 2005

Jan 28, 2002

10/059852

Robert S. Glass - Livermore CA, US
Tae H. Lee - Naperville IL, US

The Regents of the University of California - Oakland CA

B32B 900

428336, 428432, 428469, 428702, 428701, 428446, 428698, 428699, 428697, 4283105, 4283122, 4283128

A dense or porous coating of material is deposited onto a substrate by forcing a colloidal suspension through an ultrasonic nebulizer and spraying a fine mist of particles in a carrier medium onto a sufficiently heated substrate. The spraying rate is essentially matched to the evaporation rate of the carrier liquid from the substrate to produce a coating that is uniformly distributed over the surface of the substrate. Following deposition to a sufficient coating thickness, a single sintering step may be used to produce a dense ceramic coating. Using this method, coatings ranging in thickness from about one to several hundred microns can be obtained. By using a plurality of compounds in the colloidal suspension, coatings of mixed composition can be obtained. By using a plurality of solutions and separate pumps and a single or multiple ultrasonic nebulizer(s), and varying the individual pumping rates and/or the concentrations of the solutions, a coating of mixed and discontinuously graded (e. g. , stepped) or continuously graded layers may be obtained.

7141671, Nov 28, 2006

Feb 13, 2004

10/779157

Mathai Mammen - Redwood Shores CA, US
Sarah Dunham - South Yarra, AU
Adam Hughes - Belmont CA, US
Tae Weon Lee - Palo Alto CA, US
Craig Husfeld - Redwood City CA, US
Eric Stangeland - Pacifica CA, US
Yan Chen - Burlingame CA, US

Theravance, Inc. - South San Francisco CA

C07D 211/56
C07D 211/72
A61K 31/47
A61K 31/445

546224, 546304, 514312, 514317

This invention provides biphenyl derivatives of formula I:.

D537318, Feb 27, 2007

Dec 19, 2005

29/245125

Fang-Chang Fan - Chia-Yi, TW
Tae Hwan Lee - Corona CA, US

Eversafety Precision Industry (Tianjin) Co., Ltd. - Tianjin
Copper Creek Inc. - Corona CA

0806

D 8308

D542114, May 8, 2007

Jan 4, 2006

29/251067

Fang-Chang Fan - Chia-Yi, TW
Tae Hwan Lee - Corona CA, US

Eversafety Precision Industry (Tianjin) Co., Ltd. - Tianjin
Copper Creek Inc. - Corona CA

0806

D 8308

20020114873, Aug 22, 2002

Feb 19, 2001

09/788799

Tae Lee - Flushing NY, US

A23L001/238

426/589000

The present invention relates to an herbal sauce for food prepared by providing an initial mixture of Polygoni Multiflori Radix, Acanthopanacis Cortex, Angelicae Gigantis Radix, Zingiberis Rhizoma, Cinnamomi Cortex Spissus, Glycyrrhizae Radix and Cnidii Rhizoma, soaking the initial mixture in water, heating the initial mixture with the water, filtering the liquified mixture and adding a small amount of garlic powder to the aqueous extract. The present invention also relates to a process for preparing the herbal sauce for food and various products containing the same. The herbal sauce for food of the present invention has a distinctive flavor and aroma obtained by the specific combination of Oriental herbs. The herbal sauce for food of the present invention can be used for various foods and for various applications.

20030129649, Jul 10, 2003

Aug 21, 2001

09/935061

Brian Kobilka - Palo Alto CA, US
Pejman Ghanouni - Menlo Park CA, US
Tae Lee - Palo Alto CA, US

G01N033/53
G01N033/567
C12M001/34

435/007100, 435/007200, 435/287200

The present invention provides methods and compositions for detection of compounds that have activity in modulating G protein-coupled receptor (GPCR) activity, e.g., agonists, and antagonists. The detection method is based upon detection of a conformational change in a GPCR upon interaction with a ligand. Conformational change of the GPCR upon ligand interaction can be accomplished by modifying the GPCR to have a bound detectable label so that ligand interaction results in a conformational change in the GPCR that is detected by a change in detectable signal from the detectable label. Conformational change of the GPCR upon ligand interaction can also be detected by detecting a change in the accessibility of a protease cleavage site to protease cleavage, where the protease cleavage site is naturally-occurring in the GPCR or introduced into the GPCR. The conformational assays of the invention provide for high-throughput screening,