US Patent:
20110319378, Dec 29, 2011
Inventors:
Michael David BARTBERGER - Sherman Oaks CA, US
Ana GONZALEZ BUENROSTRO - San Mateo CA, US
Hilary Plake BECK - San Carlos CA, US
Xiaoqi CHEN - Palo Alto CA, US
Richard Victor CONNORS - Pacifica CA, US
Jeffrey DEIGNAN - San Francisco CA, US
Jason DUQUETTE - Millbrae CA, US
John EKSTEROWICZ - San Francisco CA, US
Benjamin FISHER - San Mateo CA, US
Brian Matthew FOX - Brisbane CA, US
Jiasheng FU - Foster City CA, US
Zice FU - Foster City CA, US
Felix GONZALEZ LOPEZ DE TURISO - San Mateo CA, US
Michael GRIBBLE, JR. - San Francisco CA, US
Darin James GUSTIN - Half Moon Bay CA, US
Julie Anne HEATH - Orinda CA, US
Xin HUANG - Wellesley MA, US
Xianyun JIAO - Belmont WA, US
Michael G. JOHNSON - San Francisco CA, US
Frank KAYSER - San Francisco CA, US
David John KOPECKY - San Francisco CA, US
Sujen LAI - Burlingame CA, US
Yihong LI - Millbrae CA, US
Zhihong LI - Millbrae CA, US
Jiwen LIU - Foster City CA, US
Jonathan Dante LOW - Tarzana CA, US
Brian Stuart LUCAS - San Francisco CA, US
Zhihua MA - Foster City CA, US
Lawrence McGEE - Pacifica CA, US
Joel McINTOSH - Pacifica CA, US
Dustin McMINN - Pacifica CA, US
Julio Cesar MEDINA - San Carlos CA, US
Jeffrey Thomas MIHALIC - San Francisco CA, US
Steven Howard Olson - Foster City CA, US
Yosup REW - Foster City CA, US
Philip Marley ROVETO - San Francisco CA, US
Daqing SUN - Foster City CA, US
Xiaodong WANG - Millbrae CA, US
Yingcai WANG - Millbrae CA, US
Xuelei YAN - Foster City CA, US
Ming YU - Foster City CA, US
Jiang ZHU - Palo Alto CA, US
Assignee:
AMGEN INC. - Thousand Oaks CA
International Classification:
A61K 31/451
C07D 413/06
A61K 31/5377
C07D 401/06
A61K 31/454
C07D 417/06
A61K 31/541
A61K 31/4545
C07D 413/12
C07D 471/10
A61K 31/438
C07D 409/04
A61K 31/4535
A61K 31/496
C07D 279/02
C07D 498/08
A61K 31/5386
A61K 31/549
C07D 498/16
A61K 31/437
A61P 35/00
C07D 211/40
US Classification:
5142102, 546221, 514327, 544130, 5142355, 546208, 514326, 544 582, 5142278, 546209, 546194, 514318, 546216, 5142372, 546 17, 514278, 546213, 544360, 51425312, 544 3, 5142222, 544105, 5142305, 544 11, 5142228, 546 90, 514291
Abstract:
The present invention provides MDM2 inhibitor compounds of Formula I,