Min J Lee

6943167, Sep 13, 2005

Aug 29, 2002

10/230974

Vincent Huber - Seattle WA, US
Jan Urban - San Diego CA, US
Hiroshi Nakanishi - San Diego CA, US
Masakatsu Eguchi - Bellevue WA, US
Jessymol Mathew - Cary NC, US
Min Sang Lee - Carlsbad CA, US

Myriad Genetics, Inc. - Salt Lake City UT

C07D473/00
A61K031/495

5142521, 544271

Compounds which mimic the secondary structure of helical regions of biologically active peptides and proteins having the following structure: including pharmaceutically acceptable salts and stereoisomers thereof, wherein Y, A, B, Rand Rare as defined herein. Such compounds have utility over a wide range of applications, including use as diagnostic and therapeutic agents. In particular, compounds of this invention, and pharmaceutical compositions containing the same, are neurokinin (tachykinin) antagonists. Libaries contaning the compounds of this invention are also disclosed, as well as methods for screening such libaries identify biologically active members.

7008941, Mar 7, 2006

May 16, 2002

10/150481

Jan Urban - Kirkland WA, US
Hiroshi Nakanishi - Newcastle WA, US
Min S. Lee - Sammamish WA, US

Myriad Genetics, Inc. - Salt Lake City UT

G01N 33/53
G08D 498/04

5142242, 514249, 514250, 5142305, 435 71, 436518, 544 14, 544 95, 544345, 544350

Conformationally constrained compounds which mimic the secondary structure of reverse-turn regions of biologically active peptides and proteins having the following structure are disclosed: wherein A, B, X, R, and Rare as defined herein. Such compounds have utility over a wide range of fields, including use as diagnostic and therapeutic agents. In particular, compounds of this invention are useful in pharmaceutical compositions as anti-inflammatory agents as well as inhibitors of central nervous disorders. Libraries containing the compounds of this invention are also disclosed, as well as methods for screening the same to identify biologically active members.

7405212, Jul 29, 2008

May 3, 2005

11/121337

Vincent Huber - Seattle WA, US
Jan Urban - San Diego CA, US
Hiroshi Nakanishi - San Diego CA, US
Masakatsu Eguchi - Bellevue WA, US
Jessymol Mathew - Cary NC, US
Min Sang Lee - Carlsbad CA, US

Myriad Genetics, Inc. - Salt Lake City UT

C07D 498/08
C07D 263/00

5142342, 514249, 544145, 544350

Compounds which mimic the secondary structure of helical regions of biologically active peptides and proteins having the following structure:.

7653490, Jan 26, 2010

Jun 13, 2002

10/172485

Daniel S. Sem - San Diego CA, US
Maurizio Pellecchia - San Diego CA, US
Qing Dong - San Diego CA, US
Mark Kelly - San Diego CA, US
Min S. Lee - Carlsbad CA, US

Triad Liquidating Company LLC - Rancho Santa Fe CA

G06F 7/00

702 19, 702 20, 703 11, 703 13, 707102, 530350

The invention provides a method for obtaining a binding compound for a protein family, wherein the members of the protein family bind a common ligand. The method includes the steps of (a) providing a sample containing a protein from the protein family, a first ligand and a second ligand under conditions wherein the first ligand, the second ligand and the protein form a bound complex; (b) detecting magnetization transfer between the first ligand and the second ligand in the bound complex, thereby determining that the two ligands are proximal in the bound complex; and (c) obtaining a candidate binding compound including the first ligand, or a fragment thereof linked to the second ligand, or a homolog thereof, whereby the population contains binding compounds that bind to members of the protein family.

7765393, Jul 27, 2010

Jul 11, 2006

11/484979

Min Eig Lee - Palo Alto CA, US
Chih-Yi Chen - San Jose CA, US
Huynh Duc Mai - Milpitas CA, US
Pradeep Kalra - San Jose CA, US

Network Appliance, Inc. - Sunnyvale CA

G06F 9/00

713 2, 714 6

An IBM PC compatible processing system typically has a BIOS installed as system firmware. During a boot process of the processing system, the BIOS loads a boot loader from one of the boot media, i. e. , hard drives, floppy disks, CDs, USB flash memories, taps, etc. and passes control of the boot loader, the boot loader then loads an OS from the boot media. The present invention takes advantage of the higher reliability and availability provided by the system flash memory and stores a boot loader as system firmware in the system flash memory. Further, it provides changes in the BIOS boot process to load the boot loader from system memory, the ROM, for example, without relying on boot media. With this new process, the boot loader can be loaded even when the boot media is corrupt, defective or un-initialized.

8173370, May 8, 2012

Feb 7, 2008

12/027954

Paul A. Oeth - San Diego CA, US
Mathias Ehrich - San Diego CA, US
Min S. Lee - San Diego CA, US

Sequenom, Inc. - San Diego CA

C12Q 1/68
C12P 19/34

435 612, 435 61, 435 611

The invention in part provides nucleic acid-based assays, which are particularly useful for non-invasive prenatal testing. The invention in part provides compositions and methods for RhD typing, detecting the presence of fetal nucleic in a sample, determining the relative amount of fetal nucleic acid in a sample and determining the sex of a fetus, wherein each of the assays may be performed alone or in combination.

20040102476, May 27, 2004

Nov 25, 2002

10/305252

Tai Chan - Palo Alto CA, US
Wilma Tamraz - San Jose CA, US
Min Lee - Saratoga CA, US

A61K031/445
A61K031/19

514/317000, 514/557000

The present invention provides opioid formulations suitable for long-term delivery to a subject. The formulation of the invention comprises an opioid or opioid derivative (e.g., morphine, hydromorphone, fentanyl or a fentanyl congener), and an aqueous solvent comprising a low molecular weight carboxylic acid (e.g., C, C). The invention thus provides for formulations comprising morphine, hydromorphone, fentanyl or fentanyl congeners in concentrations significantly in excess of conventional aqueous formulations, e.g., on the order about 2-fold to about 10,000-fold greater than conventional formulations, e.g., currently commercially available formulations.

20060079517, Apr 13, 2006

Dec 2, 2005

11/292611

Jan Urban - Kirkland WA, US
Hiroshi Nakanishi - Newcastle WA, US
Min Lee - Sammamish WA, US

Myriad Genetics, Incorporated - Salt Lake City UT

A61K 31/5415
A61K 31/498

514224200, 514249000

Conformationally constrained compounds which mimic the secondary structure of reverse-turn regions of biologically active peptides and proteins having the following structure are disclosed: wherein A, B, X, R, and Rare as defined herein. Such compounds have utility over a wide range of fields, including use as diagnostic and therapeutic agents. In particular, compounds of this invention are useful in pharmaceutical compositions as anti-inflammatory agents as well as inhibitors of central nervous disorders. Libraries containing the compounds of this invention are also disclosed, as well as methods for screening the same to identify biologically active members.