Min Jin Lee

D504003, Apr 19, 2005

Sep 12, 2003

29/189951

Min Jae Lee - Rowland Heights CA, US

0203

D 2882

6943167, Sep 13, 2005

Aug 29, 2002

10/230974

Vincent Huber - Seattle WA, US
Jan Urban - San Diego CA, US
Hiroshi Nakanishi - San Diego CA, US
Masakatsu Eguchi - Bellevue WA, US
Jessymol Mathew - Cary NC, US
Min Sang Lee - Carlsbad CA, US

Myriad Genetics, Inc. - Salt Lake City UT

C07D473/00
A61K031/495

5142521, 544271

Compounds which mimic the secondary structure of helical regions of biologically active peptides and proteins having the following structure: including pharmaceutically acceptable salts and stereoisomers thereof, wherein Y, A, B, Rand Rare as defined herein. Such compounds have utility over a wide range of applications, including use as diagnostic and therapeutic agents. In particular, compounds of this invention, and pharmaceutical compositions containing the same, are neurokinin (tachykinin) antagonists. Libaries contaning the compounds of this invention are also disclosed, as well as methods for screening such libaries identify biologically active members.

7405212, Jul 29, 2008

May 3, 2005

11/121337

Vincent Huber - Seattle WA, US
Jan Urban - San Diego CA, US
Hiroshi Nakanishi - San Diego CA, US
Masakatsu Eguchi - Bellevue WA, US
Jessymol Mathew - Cary NC, US
Min Sang Lee - Carlsbad CA, US

Myriad Genetics, Inc. - Salt Lake City UT

C07D 498/08
C07D 263/00

5142342, 514249, 544145, 544350

Compounds which mimic the secondary structure of helical regions of biologically active peptides and proteins having the following structure:.

7653490, Jan 26, 2010

Jun 13, 2002

10/172485

Daniel S. Sem - San Diego CA, US
Maurizio Pellecchia - San Diego CA, US
Qing Dong - San Diego CA, US
Mark Kelly - San Diego CA, US
Min S. Lee - Carlsbad CA, US

Triad Liquidating Company LLC - Rancho Santa Fe CA

G06F 7/00

702 19, 702 20, 703 11, 703 13, 707102, 530350

The invention provides a method for obtaining a binding compound for a protein family, wherein the members of the protein family bind a common ligand. The method includes the steps of (a) providing a sample containing a protein from the protein family, a first ligand and a second ligand under conditions wherein the first ligand, the second ligand and the protein form a bound complex; (b) detecting magnetization transfer between the first ligand and the second ligand in the bound complex, thereby determining that the two ligands are proximal in the bound complex; and (c) obtaining a candidate binding compound including the first ligand, or a fragment thereof linked to the second ligand, or a homolog thereof, whereby the population contains binding compounds that bind to members of the protein family.

8173370, May 8, 2012

Feb 7, 2008

12/027954

Paul A. Oeth - San Diego CA, US
Mathias Ehrich - San Diego CA, US
Min S. Lee - San Diego CA, US

Sequenom, Inc. - San Diego CA

C12Q 1/68
C12P 19/34

435 612, 435 61, 435 611

The invention in part provides nucleic acid-based assays, which are particularly useful for non-invasive prenatal testing. The invention in part provides compositions and methods for RhD typing, detecting the presence of fetal nucleic in a sample, determining the relative amount of fetal nucleic acid in a sample and determining the sex of a fetus, wherein each of the assays may be performed alone or in combination.

20080096766, Apr 24, 2008

Jun 14, 2007

11/763211

Min LEE - San Diego CA, US

Sequenom, Inc. - San Diego CA

C40B 20/08

506006000

The invention relates to methods and kits for the amplification, detection and quantification of a nucleic acid from a sample. The methods of the invention may be used in a wide range of applications, including, but not limited to, the detection and quantification of fetal nucleic acid from maternal plasma, the detection and quantification of circulating nucleic acids from neoplasms (malignant or non-malignant), accurate pooling analysis for low frequency alleles, or any other application requiring sensitive quantitative analysis of nucleic acids.

20090317817, Dec 24, 2009

Mar 10, 2009

12/401493

Paul Andrew Oeth - San Diego CA, US
Payam Mahboubi - San Diego CA, US
Min Seob Lee - San Diego CA, US

Sequenom, Inc. - San Diego CA

C12Q 1/68

435 6

Provided herein are compositions, processes and kits for noninvasive, early determination of fetal sex from, and/or amount of fetal nucleic acid in, an extracellular nucleic acid sample from a pregnant female. Such compositions, processes and kits are useful for detection of low genomic copy numbers of male fetal nucleic acid in a high copy number background of female nucleic acid, thereby determining the sex of a fetus and/or amount of fetal nucleic acid in a sample.

20110294699, Dec 1, 2011

Aug 28, 2008

12/674403

Min Seob Lee - San Diego CA, US
Yanfeng Yang - Dublin CA, US

SEQUENOM, INC. - San Diego CA

C40B 30/10
C12Q 1/68

506 12, 435 612, 435 611

Provided herein are products and processes for the amplification, detection and sequencing of short-stranded nucleic acid in the presence of a high background of long-stranded genomic material (e.g., host or maternal nucleic acids). The methods rely on the use of inside and outside primers introduced at varying concentrations, as well as universal amplification reactions that preferentially amplify short, low copy number nucleic acid.