Ly Lee Phones & Addresses
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Moreno Valley, CA
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Riverside, CA
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San Fernando, CA
Publications
Us Patents
Lipid-Polymer Hybrid Nanoparticle Biochip And Application Thereof
View pageUS Patent:
20180179577, Jun 28, 2018
Filed:
Dec 5, 2017
Appl. No.:
15/831998
Inventors:
Jiaming Hu - Arcadia CA, US
Yan Sheng - Yantai, CN
Ly James Lee - Columbus OH, US
Yan Sheng - Yantai, CN
Ly James Lee - Columbus OH, US
International Classification:
C12Q 1/68
Abstract:
The present invention provides a novel lipid-polymer hybrid nanoparticle (LPHN) biochip. The LPHN biochip comprises a gold coating substrate with a surface layer on the gold coating and a nanoparticle, wherein the nanoparticle anchors on the surface layer and encapsulates labeling moieties which comprise molecular beacons (MB), Toehold-initiated molecular beacons (Ti-MB), biomolecules or components for performing catalyzed hairpin DNA circuit (CHDC), and quantum dots. A method of detecting the presence of a disease or condition in a subject by the lipid-polymer hybrid nanoparticle biochip is also disclosed in the specification.