US Patent:
20180125958, May 10, 2018
Inventors:
- New York NY, US
Leena Shriram Bagle - Edgewater NJ, US
Amardeep Singh Bhupender Bhalla - Montvale NJ, US
Miguel Angel Garcia - Midland Park NJ, US
Lei Hu - New City NY, US
Lakshmi Khandke - Nanuet NY, US
Avvari Krishna Prasad - Chapel Hill NC, US
Cindy Xudong Yang - Tappan NY, US
International Classification:
A61K 39/09
A61K 39/39
Abstract:
The invention relates to immunogenic compositions comprising a capsular polysaccharide (CP) from commonly referred to as group B (GBS), conjugated to a carrier protein, and optionally including an aluminum-based adjuvant. The invention further relates to methods for inducing an immune response in subjects against GBS and/or for reducing or preventing invasive GBS disease in subjects using the compositions disclosed herein. The resulting antibodies can be used to treat or prevent GBS infection via passive immunotherapy.