Jinbo Hu Phones & Addresses
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2667 Orchard Ave, Los Angeles, CA 90007 (323) 737-6807
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2611 Orchard Ave, Los Angeles, CA 90007
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1173 28Th St, Los Angeles, CA 90007 (213) 746-5718
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1150 28Th St, Los Angeles, CA 90007
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1146 30Th St, Los Angeles, CA 90007
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Washington, DC
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1150 W 28Th St APT 8, Los Angeles, CA 90007 (213) 361-9245
Work
Position:
Protective Service Occupations
Education
Degree:
High school graduate or higher
Publications
Us Patents
Method For Expedient Synthesis Of [18F]-Labeled Α-Trifluoromethyl Ketones
View pageUS Patent:
6872855, Mar 29, 2005
Filed:
Nov 26, 2003
Appl. No.:
10/721423
Inventors:
G. K. Surya Prakash - Hacienda Heights CA, US
Mian M. Alauddin - Alhambra CA, US
Jinbo Hu - Los Angeles CA, US
Peter S. Conti - Pasadena CA, US
George A. Olah - Beverly Hills CA, US
Mian M. Alauddin - Alhambra CA, US
Jinbo Hu - Los Angeles CA, US
Peter S. Conti - Pasadena CA, US
George A. Olah - Beverly Hills CA, US
Assignee:
University of Southern California - Los Angeles CA
International Classification:
C07C045/00
G21G001/06
G06K009/00
G21G001/06
G06K009/00
US Classification:
568323, 568325, 376168, 382130, 382131
Abstract:
The present invention is directed to a convenient method of synthesizing radiolabeled α-trifluoromethyl ketones by a fluorination reaction. The present invention also relates to imaging agents and markers for identifying cell proliferation, or viral infection. The markers and imaging agents including the radiolabeled α-trifluoromethyl ketones that are prepared by the present method.
Methods For Nucleophilic Fluoromethylation
View pageUS Patent:
7087789, Aug 8, 2006
Filed:
Jan 12, 2004
Appl. No.:
10/755902
Inventors:
G. K. Surya Prakash - Hacienda Heights CA, US
Jinbo Hu - Los Angeles CA, US
George A. Olah - Beverly Hills CA, US
Jinbo Hu - Los Angeles CA, US
George A. Olah - Beverly Hills CA, US
Assignee:
University of Southern California - Los Angeles CA
International Classification:
C07C 319/00
US Classification:
568 56, 568323, 568437
Abstract:
A novel, convenient and efficient method for trifluoromethylation of substrate compounds is disclosed. Particularly, alkoxide and hydroxide induced nucleophilic trifluoromethylation of carbonyl compounds, disulfides and other electrophiles, using phenyl trifluoromethyl sulfone PhSOCF(or sulfoxide PhSOCF) is disclosed. A method of both symmetrical and unsymmetrical anti-2,2-difluoropropan-1,3-diols with high diastereoselectivity (up to 94% de) is disclosed using difluoromethyl phenyl sulfone. This unusual type of high diastereoselectivity was obtained via an intramolecular charge-charge repulsion effect rather than the traditional steric control (based on the Cram's rule). Thus, difluoromethyl phenyl sulfone can be used as a novel difluoromethylene dianion species (“CF2”), which can couple two electrophiles (such as diphenyl disulfide or non-enolizable aldehydes) to give new difluoromethylenated products.
Magnesium Mediated Preparation Of Fluorinated Alkyl Silanes
View pageUS Patent:
20030153778, Aug 14, 2003
Filed:
Nov 27, 2002
Appl. No.:
10/305025
Inventors:
Jinbo Hu - Los Angeles CA, US
George Olah - Beverly Hills CA, US
George Olah - Beverly Hills CA, US
International Classification:
C07F007/02
US Classification:
556/488000
Abstract:
An efficient method is disclosed for the preparation of trifluoromethyl- and difluoromethylsilanes using magnesium metal mediated reductive tri- and difluoromethylation of chlorosilanes with tri- and difluoromethyl sulfides, sulfoxides, and sulfones. One byproduct of the process is diphenyl disulfide. Since phenyl trifluoromethyl sulfone, sulfoxide and sulfide are readily prepared from readily available trifluoromethane and diphenyl disulfide, the method can be considered “pseudo-catalytic” for the preparation of (trifluoromethyl)trimethylsilane from environmentally benign trifluoromethane.