Jie L Wu

6703514, Mar 9, 2004

May 13, 2003

10/437768

Jie Wu - Ridgewood NJ
Zhen Yang - Ridgewood NJ
Reza Fathi - Hohokus NJ
Qiang Zhu - Ridgewood NJ
Lisha Wang - Ridgewood NJ

Vivo Quest, Inc. - Valley Cottage NY

C07D31102

549284, 549285

4-thio substituted coumarin derivatives and coumarin dimers are provided, as well as processes for their preparation. A synthetic process for the preparation of 4-thio substituted coumarin derivatives is provided using mild reaction conditions, which maintains a high substituent tolerance and is appropriate for use in solid phase syntheses for producing a library of 4-thio substituted coumarin derivatives for biological screening.

7148253, Dec 12, 2006

Jan 6, 2004

10/752654

Jie Wu - Ridgewood NJ, US
Zhen Yang - Ridgewood NJ, US
Reza Fathi - Hohokus NJ, US
Qiang Zhu - Ridgewood NJ, US

XTL Biopharmaceuticals Ltd. - Rehovet

A61K 31/35

514456, 514457, 549284, 549285

4-Thio substituted coumarin derivatives, 4,5-dithio substituted coumarin derivatives, and coumarin dimers are provided, as well as processes for their preparation. The invention also provides a method and composition for the treatment of hepatitis C virus (HCV) by adiministering 4-thio substituted coumarin derivatives, 4,5-dithio substituted coumarin derivatives, and coumarin dimers.

20180037554, Feb 8, 2018

Feb 1, 2016

15/549242

- Rahway NJ, US
Rongze Kuang - Green Brook NJ, US
Yeon-Hee Lim - Piscataway NJ, US
Michael Man-Chu Lo - Bedminister, NJ
Pauline C. Ting - New Providence NJ, US
Purakkattle Biju - Piscataway NJ, US
Manuel de Lera Ruiz - Perkasie PA, US
Sylvia J. Degrado - Scotch Plains NJ, US
Alexander L. Tung - Bensalem PA, US
Timothy J. Henderson - Natick MA, US
Liwu Hong - East Brunswick NJ, US
Jae-Hun Kim - Scotch Plains NJ, US
Dong Won-Shik Kim - Rockville MD, US
Joe Lee - Rahway NJ, US
Jie Wu - Scotch Plains NJ, US
Heping Wu - Edison NJ, US
Yushi Xiao - Rahway NJ, US
Tao Yu - Edison NJ, US
Gang Zhou - Bridgewater NJ, US
Xiaohong Zhu - Edison NJ, US
Kevin D. McCormick - Basking Ridge NJ, US
Jayaram R. Tagat - Westfield NJ, US
Dong Xiao - Warren NJ, US
Tanweer Khan - Bridgewater NJ, US
Jianhua Cao - Edison NJ, US
Michael Berlin - Rahway NJ, US
Yonglian Zhang - Metuchen, NJ

Merck Sharp & Dohme Corp. - Rahway NJ

C07D 239/84
C07D 401/14
C07D 413/12
C07D 417/12
C07D 405/12
C07D 417/14
C07D 413/14
C07D 471/04
C07D 401/12
C07D 403/12

The present invention is directed to compounds of generic formula I: or pharmaceutically acceptable salts thereof that are believed to be useful as an A2A-receptor antagonist.