In Kang Kim

6699827, Mar 2, 2004

Jun 13, 2001

09/878963

In Kyu Kim - Rancho Cucamonga CA, 91730

C11D 1825

510350, 510289, 510340, 510341, 510356, 510413, 510421, 510501

A provided novel colloid active component, a method for manufacturing colloid aluminum silica gel, and a surfactant containing the same are disclosed for solving water and land pollution, being safe to a human and the ecosystem, and adding economic value and applicability for the industrial use, wherein the method comprises the steps of: (a) dissolving a mixture of aluminum oxide, silicic acid, potassium, iron oxide, sulfuric acid and water into sulfuric acid; (b) adding potassium sulfate solution into the solution, and stirring at a low temperature to produce compositions with soluble aluminum double salt; (c) purifying the compositions to get very pure and dense aluminum potassium sulfate; (d) adding aluminum silicate and water to produce alkali metal polysilicate-sulfate water salt chelate; (e) polymerizing and precipitating the resultant at a low temperature to produce pectograph of aluminum silicate sieve; (f) producing chelate by adding Mgo, Fe O , Ca(OH) , NaOH, KOH, and distilled water in sequence; (g) purifying and drying the chelate to get dried microsphere; (h) melting the microsphere, cooling, hardening, and mixing with thin sulfuric acid; (i) polymerizing, cleansing, heating, dehydrating, or drying, and performing vapor treatment to obtain powdered and highly absorptive aluminum silicate molecular sieve with under 1 m of granularity; and, (j) polymerizing the aluminum silicate molecular sieves with each other until they are matured to be a highly dense heel.

6958362, Oct 25, 2005

Jul 26, 2004

10/898230

In Kyu Kim - Rancho Cucamonga CA, US

C01B033/14

516 34, 510508

A novel colloid active component, a method for manufacturing colloid aluminum silica gel, and a surfactant containing the same are disclosed, wherein the method includes the steps of: (a) dissolving a mixture of aluminum oxide, silicic acid, potassium, iron oxide, sulfuric acid and water into sulfuric acid; (b) adding potassium sulfate solution into the solution, and stirring at a low temperature to produce compositions with soluble aluminum double salt; (c) purifying the compositions to obtain a very pure and dense aluminum potassium sulfate; (d) adding aluminum silicate and water to produce alkali metal polysilicate-sulfate water salt chelate; (e) polymerizing and precipitating the resultant; (f) adding Mgo, FeO, Ca(OH), NaOH, KOH, and distilled water; (g) purifying and drying the chelate; (h) mixing the resulting microsphere, with sulfuric acid; (i) further treating the mixture and performing vapor treatment to obtain aluminum silicate molecular sieve; and, (j) polymerizing the aluminum silicate molecular sieves to a highly dense heel.

7202246, Apr 10, 2007

Jun 8, 2005

11/147520

Zhenkun Ma - Dallas TX, US
In Ho Kim - Lewisville TX, US
Jing Li - Dallas TX, US

Cumbre Pharmaceuticals Inc. - Dallas TX

C07D 225/04
A61K 31/495
A61P 31/04

514250, 540453, 540457

Compounds of the current invention relate to rifamycin derivatives having antimicrobial activities, including activities against drug-resistant microorganisms. More specifically, compounds of the current invention relate to a series of novel spiro rifamycin derivatives which have demonstrated potent antimicrobial activity.

7229996, Jun 12, 2007

Jul 21, 2005

11/186187

Zhenkun Ma - Dallas TX, US
Jing Li - Dallas TX, US
Susan Harran - Dallas TX, US
Yong He - Arlington TX, US
Keith P. Minor - Dallas TX, US
In Ho Kim - Lewisville TX, US
Charles Z. Ding - Plano TX, US
Jamie C. Longgood - Carrolton TX, US
Yafei Jin - Dallas TX, US
Keith D. Combrink - Fort Worth TX, US

Cumbre Pharmaceuticals Inc. - Dallas TX

C07D 498/08
A61K 31/4709
A61P 31/04

51425217, 514278, 514306, 540459

Novel rifamycin derivatives of formula I (both hydroquinone and corresponding quinone (C-C) forms):.

7247634, Jul 24, 2007

Jan 12, 2005

11/034195

Zhenkun Ma - Dallas TX, US
Yafei Jin - Dallas TX, US
Jing Li - Dallas TX, US
Charles Z. Ding - Plano TX, US
Keith P. Minor - Dallas TX, US
Jamie C. Longgood - Carrollton TX, US
In Ho Kim - Flower Mound TX, US
Susan Harran - Dallas TX, US
Keith Combrink - Fort Worth TX, US
Timothy W. Morris - Coppell TX, US

Cumbre Pharmaceuticals Inc. - Dallas TX

C07D 498/08
A61K 31/395
A61P 31/04

51425304, 51425308, 514278, 514300, 514312, 540456

Rifamycin derivatives having antimicrobial activities, including activities against drug-resistant microorganisms are claimed in this invention. The inventive rifamycin derivatives are uniquely designed in that they have a rifamycin moiety covalently linked to a linker group through the C-3 carbon of the rifamycin moiety and the linker is, in turn covalently linked to a therapeutic moiety or antibacterial agent/pharmacophore. The therapeutic moiety can be a quinolone, an oxazolidinone, a macrolide, an aminoglycoside, a tetracycline core or a structure/pharmacophore associated with an antibacterial agent.

20040152611, Aug 5, 2004

Dec 30, 2003

10/747035

In Kim - Rancho Cucamonga CA, US

C11D001/00

510/350000

A provided novel colloid active component, a method for manufacturing colloid aluminum silica gel, and a surfactant containing the same are disclosed for solving water and land pollution, being safe to a human and the ecosystem, and adding economic value and applicability for the industrial use, wherein the method comprises the steps of: (a) dissolving a mixture of aluminum oxide, silicic acid, potassium, iron oxide, sulfuric acid and water into sulfuric acid; (b) adding potassium sulfate solution into the solution, and stirring at a low temperature to produce compositions with soluble aluminum double salt; (c) purifying the compositions to get very pure and dense aluminum potassium sulfate; (d) adding aluminum silicate and water to produce alkali metal polysilicate-sulfate water salt chelate; (e) polymerizing and precipitating the resultant at a low temperature to produce pectograph of aluminum silicate sieve; (f) producing chelate by adding Mgo, FeO, Ca(OH), NaOH, KOH, and distilled water in sequence; (g) purifying and drying the chelate to get dried microsphere; (h) melting the microsphere, cooling, hardening, and mixing with thin sulfuric acid; (i) polymerizing, cleansing, heating, dehydrating, or drying, and performing vapor treatment to obtain powdered and highly absorptive aluminum silicate molecular sieve with under 1 m of granularity; and, (j) polymerizing the aluminum silicate molecular sieves with each other until they are matured to be a highly dense heel.

20050118624, Jun 2, 2005

Sep 30, 2004

10/954996

Zhenkun Ma - Dallas TX, US
Jing Li - Dallas TX, US
In Kim - Irving TX, US
Yafei Jin - Dallas TX, US
Anthony Lynch - Dallas TX, US
Eric Roche - Carrollton TX, US
Doug Beeman - Dallas TX, US

Cumbre Inc. - Dallas TX

C12Q001/68
C07H017/08
C07H021/04

435006000, 536024100, 536025320, 544229000, 544230000, 536007100

Fluorescent probes that have binding affinity to ribosomes. The fluorescent probes are useful tools for identifying small molecules that bind to the 50S or 30S subunits of the bacterial and other ribosomes and serve as novel ribosome inhibitors. These probes are also useful for determining the interactions between a specific ligand and the ribosome.

20050239682, Oct 27, 2005

Jun 30, 2005

11/169713

In Kim - Rancho Cucamonga CA, US

C11D001/00

510499000

Provided is a surfactant containing alkanol amide condensate obtained from a reaction of 12-hydroxy-cis-9-octadecanoic acid, alkanol amine and water.