US Patent:
20100190766, Jul 29, 2010
Inventors:
Heinz E. Moser - South San Francisco CA, US
Qing Lu - Foster City CA, US
Phillip A. Patten - Portola Valley CA, US
Dan Wang - Fremont CA, US
Ramesh Kasar - San Mateo CA, US
Stephen Kaldor - San Diego CA, US
Brian D. Patterson - San Francisco CA, US
Assignee:
Achaogen, Inc. - South San Francisco CA
International Classification:
A61K 31/165
C07C 259/06
C07D 207/16
A61K 31/40
C07C 233/78
A61K 31/166
C07D 295/155
A61K 31/5375
C07D 213/61
A61K 31/44
C07D 413/10
A61K 31/5377
C07D 417/10
C07D 233/64
A61K 31/4164
A61K 31/4406
C07D 333/24
A61K 31/381
A61K 31/54
C07D 471/04
A61K 31/437
C07D 267/10
A61K 31/553
C07C 279/14
A61K 31/155
A61P 31/04
US Classification:
51421018, 562623, 514575, 548537, 514423, 564156, 514616, 544165, 5142378, 546335, 514357, 544169, 544122, 5142358, 544120, 5142102, 5142315, 544146, 544130, 5142355, 544141, 544137, 5142368, 5142352, 544128, 544119, 5142345, 5142338, 544145, 5483381, 514400, 549 77, 514438, 544 582, 5142275, 546119, 514303, 540544, 51421101, 564237, 514634
Abstract:
Antibacterial compounds of formula (I) are provided:as well as stereoisomers, pharmaceutically acceptable salts, esters, and prodrugs thereof; pharmaceutical compositions comprising such compounds; methods of treating bacterial infections by the administration of such compounds; and processes for the preparation of such compounds.