Bin Shen from San Francisco, CA, age 75

System Architecture And Methods For Online Real-Time Auctions Of Advertising Inventory

View page

US Patent:

20220270139, Aug 25, 2022

Filed:

Mar 14, 2022

Appl. No.:

17/694247

Inventors:

- Pasadena CA, US
Bin Shen - Pasadena CA, US
Brian Schmidt - Pasadena CA, US
Jarriett Robinson - Pasadena CA, US
David Tannenbaum - Pasadena CA, US
Vadim Telyatnikov - Pasadena CA, US
Miki Rapoport - Glendale CA, US

International Classification:

G06Q 30/02
H04L 67/02

Abstract:

System architecture and methods for enabling an online real-time auction (either server-side or client-side) of advertising inventory that works in conjunction with ad serving technologies. In some implementations, the system architecture facilitates multiple parallel requests from an end-user's browser client to multiple real-time bidders who respond with a bid and advertisement that are sent to an ad serving system to be compared with other statically priced advertisements and exchange demand to determine the winning advertisements that will be displayed to the end-user. Data is aggregated for each bid and price limits are set based on the aggregations. In other implementations, all the bids from the multiple bidders are passed to the publisher for selection of a bid by the publisher.

System Architecture And Methods For Facilitating Client-Side Real-Time Auctions Of Advertising Inventory

View page

US Patent:

20210035165, Feb 4, 2021

Filed:

Oct 19, 2020

Appl. No.:

17/074249

Inventors:

Bin Shen - Pasadena CA, US
Brian Schmidt - Pasadena CA, US
Jarriett Robinson - Pasadena CA, US
David Tannenbaum - Pasadena CA, US
Vadim Telyatnikov - Pasadena CA, US

International Classification:

G06Q 30/02

Abstract:

System architecture and methods for enabling a client-side real-time auction of advertising inventory that works in conjunction with ad serving technologies. The method according to some embodiments of the present invention comprise: (i) an end-user visiting a web page wherein multiple advertisements are displayed, (ii) for each ad unit on the page, multiple parallel requests are sent from the end-user's browser client to multiple real-time bidders who respond with a bid & advertisement for each unit, (iii) the bids are compared within the end-user's browser and the winning bid is sent to an ad serving system to be compared with other statically priced advertisements and exchange demand to determine the winning advertisements that will be displayed to the end-user and (iv) data is aggregated for each bid and price limits are set based on the aggregations.

System Architecture And Methods For Facilitating Client-Side Real-Time Auctions Of Advertising Inventory

View page

US Patent:

20180285938, Oct 4, 2018

Filed:

Jun 4, 2018

Appl. No.:

15/997559

Inventors:

- Pasadena CA, US
Bin Shen - Pasadena CA, US
Brian Schmidt - Pasadena CA, US
Jarriett Robinson - Pasadena CA, US
David Tannenbaum - Pasadena CA, US
Vadim Telyatnikov - Pasadena CA, US

International Classification:

G06Q 30/02

Abstract:

System architecture and methods for enabling a client-side real-time auction of advertising inventory that works in conjunction with ad serving technologies. The method according to some embodiments of the present invention comprise: (i) an end-user visiting a web page wherein multiple advertisements are displayed, (ii) for each ad unit on the page, multiple parallel requests are sent from the end-user's browser client to multiple real-time bidders who respond with a bid & advertisement for each unit, (iii) the bids are compared within the end-user's browser and the winning bid is sent to an ad serving system to be compared with other statically priced advertisements and exchange demand to determine the winning advertisements that will be displayed to the end-user and (iv) data is aggregated for each bid and price limits are set based on the aggregations.

System Architecture And Methods For Facilitating Client-Side Real-Time Auctions Of Advertising Inventory

View page

US Patent:

20170103428, Apr 13, 2017

Filed:

Oct 25, 2016

Appl. No.:

15/333513

Inventors:

- Pasadena CA, US
Bin Shen - Pasadena CA, US
Brian Schmidt - Pasadena CA, US
Jarriett Robinson - Pasadena CA, US
David Tannenbaum - Pasadena CA, US
Vadim Telyatnikov - Pasadena CA, US

International Classification:

G06Q 30/02

Abstract:

System architecture and methods for enabling a client-side real-time auction of advertising inventory that works in conjunction with ad serving technologies. The method according to some embodiments of the present invention comprise: (i) an end-user visiting a web page wherein multiple advertisements are displayed, (ii) for each ad unit on the page, multiple parallel requests are sent from the end-user's browser client to multiple real-time bidders who respond with a bid & advertisement for each unit, (iii) the bids are compared within the end-user's browser and the winning bid is sent to an ad serving system to be compared with other statically priced advertisements and exchange demand to determine the winning advertisements that will be displayed to the end-user and (iv) data is aggregated for each bid and price limits are set based on the aggregations.

System Architecture And Methods For Facilitating Client-Side Real-Time Auctions Of Advertising Inventory

View page

US Patent:

20150051986, Feb 19, 2015

Filed:

Aug 15, 2014

Appl. No.:

14/461265

Inventors:

- Pasadena CA, US
Bin Shen - Pasadena CA, US
Brian Schmidt - Pasadena CA, US
Jarriett Robinson - Pasadena CA, US
David Tannenbaum - Pasadena CA, US
Vadim Telyatnikov - Pasadena CA, US

International Classification:

G06Q 30/02

US Classification:

705 1471

Abstract:

System architecture and methods for enabling a client-side real-time auction of advertising inventory that works in conjunction with ad serving technologies. The method according to some embodiments of the present invention comprise: (i) an end-user visiting a web page wherein multiple advertisements are displayed, (ii) for each ad unit on the page, multiple parallel requests are sent from the end-user's browser client to multiple real-time bidders who respond with a bid & advertisement for each unit, (iii) the bids are compared within the end-user's browser and the winning bid is sent to an ad serving system to be compared with other statically priced advertisements and exchange demand to determine the winning advertisements that will be displayed to the end-user and (iv) data is aggregated for each bid and price limits are set based on the aggregations.

Cystine Knot Peptides That Bind Alpha-V-Beta-6 Integrin

View page

US Patent:

20140271469, Sep 18, 2014

Filed:

May 21, 2014

Appl. No.:

14/283830

Inventors:

- Palo Alto CA, US
Sanjiv S. Gambhir - Stanford CA, US
Benjamin J. Hackel - Edina MN, US
Robert Teed - Menlo Park CA, US
Bin Shen - Mountain View CA, US
Frederick T Chin - Sunnyvale CA, US
Zhen Cheng - Mountain View CA, US

Assignee:

The Board of Trustees of the Leland Stanford Junior University - Palo Alto CA

International Classification:

C07K 14/00
G01N 33/574
A61K 51/08

US Classification:

424 169, 530324, 514 191, 436501, 435 723, 514 37, 514 193

Abstract:

Disclosed are peptides comprising a molecular scaffold portion and a loop portion that binds to integrin αβ. This integrin is expressed on pancreatic tumors, making the peptides useful as imaging agents, among other uses. The peptides showed single-digit nanomolar dissociation constants similar to antibodies used clinically for imaging and therapy. The peptides rapidly accumulated in αβ-positive tumors, which led to excellent tumor-to-normal contrast. The peptides are specific for the targeted integrin αβreceptors expressed on orthotopic pancreatic tumors and various xenografts used. Additionally, pharmacokinetic-stabilization strategies endowed knots with rapid renal clearance, which significantly reduced off-target dosing.