US Patent:
20140274873, Sep 18, 2014
Inventors:
- Irvine CA, US
Cindy Wu - Foothill Ranch CA, US
Assignee:
ALLERGAN, INC. - Irvine CA
International Classification:
A61K 47/34
A61K 38/16
Abstract:
As described herein, controlled and sustained administration of a therapeutic agent, such as a protein through the administration of one or more microparticles, may improve treatment of conditions, such as undesirable ocular conditions. The microspheres can be formulated to provide a sustained release of a protein, while reducing the number of protein aggregates, achieving desirable release profiles, and increasing stability of the protein within the microsphere formulations.