Amy S Lee

7378427, May 27, 2008

Jun 17, 2005

11/155851

Brian Hugh Ridgway - Belmont CA, US
William Jay Moore - Collegeville PA, US
Mark Anthony Ashwell - Carlisle MA, US
William Ronald Solvibile - East Windsor NJ, US
Amy Tsai-Ting Lee - Los Altos CA, US
Molly Elizabeth Hoke - Hightstown NJ, US
Madelene Antane - West Windsor NJ, US
Amedeo A. Failli - Princeton Junction NJ, US

Wyeth - Madison NJ

A61K 31/44
C07D 221/12

514298, 546108

Synthetic methods are provided for production of compounds of the formula:.

7666220, Feb 23, 2010

Jul 7, 2006

11/482503

Michael A. Evans - Palo Alto CA, US
Gwendolyn A. Watanabe - Sunnyvale CA, US
Amy Lee - Sunnyvale CA, US
Steven L. Herbowy - Palo Alto CA, US

Nellix, Inc. - Palo Alto CA

A61F 2/06

623 125, 623 132

Embodiments provide methods and systems for treating aneurysms using filling structures filled with a curable medium. An embodiment of a method comprises positioning at least one double-walled filling structure across the aneurysm and filling the structure(s) with a filling medium so that an outer wall conforms to the inside of the aneurysm and an inner wall forms a generally tubular lumen to provide for blood flow. The lumen is supported with a balloon or other expandable device while and/or after filling. The pressure within the structure and/or in the space between an external wall of the structure and the aneurysm wall is monitored and a flow of the medium into the structure is controlled responsive to the pressure. The pressure can also be used to determine a filling endpoint. The medium is hardened while the lumen remains supported by the balloon.

8048145, Nov 1, 2011

Apr 28, 2006

11/413460

Michael A. Evans - Palo Alto CA, US
Gwendolyn A. Watanabe - Sunnyvale CA, US
Amy Lee - Sunnyvale CA, US
Steven L. Herbowy - San Francisco CA, US

Endologix, Inc. - Irvine CA

A61F 2/06

623 125, 606194, 606195, 623 132

Aneurysms are treated by filling at least one double-walled filling structure with a curable medium within the aneurysm. The filling structures may be delivered over balloon deployment mechanisms in order to shape and open tubular lumens therethrough. Scaffolds are placed into the tubular lumens in order to help maintain the shape, anchor the filling structures in place, and provide improved blood flow transition into and out of the tubular lumens.

8392538, Mar 5, 2013

Aug 1, 2012

13/564609

Amy Lee - San Mateo CA, US

Luminate, Inc. - Mountain View CA

G06F 15/16

709219, 709203, 709217

Disclosed herein are systems and methods for displaying images and contextually relevant content on a digital content platform, such as a web page. In one embodiment, for example, the systems and methods include: (1) providing a publisher of the image with a reference script for publication with the image, wherein the reference script is a computer-readable instruction that causes an end-user device to call to a content server; and (2) configuring the content server to (a) receive a request for content from the end-user device, (b) identify content that is contextually relevant to the image, (c) deliver the content to the end-user device, and (d) deliver a computer-readable instruction that causes the end-user device to perform an animation that modifies the image and displays the content in a spatial relationship with respect to the image as originally published.

20060079923, Apr 13, 2006

Aug 9, 2005

11/200947

Manik Chhabra - Stanford CA, US
Neema Hekmat - Mountain View CA, US
Peter Johnson - Mountain View CA, US
Amy Lee - Riverside CA, US

A61M 29/00

606192000

A device for occluding an aneurysm comprising: a detachable, semi-compliant, radially-expanding balloon mounted on a catheter, wherein the balloon is in fluid communication with the catheter, wherein the balloon comprises a plurality of micropores, and wherein the micropores in the balloon allow expression of a bio-adhesive fluid at a defined pressure from the inside to the outside of the balloon.

20070150041, Jun 28, 2007

May 31, 2006

11/444603

Michael Evans - Palo Alto CA, US
Gwendolyn Watanabe - Sunnyvale CA, US
Amy Lee - Sunnyvale CA, US
Steven Herbowy - San Francisco CA, US

Nellix, Inc. - Mountain View CA

A61F 2/06

623001110

Aneurysms are treated by placing a scaffold across an aneurysmal sac to provide a blood flow lumen therethrough. An aneurysmal space surrounding the scaffold is filled with one or more expandable structures which are simultaneously or sequentially expanded to fill the aneurysmal space and reduce the risk of endoluminal leaks and scaffold migration. The expandable structures are typically inflatable and delivered by delivery catheter, optionally with an inflation tube or structure attached to the expandable structure.

20090319029, Dec 24, 2009

Jun 4, 2009

12/478208

Michael A. Evans - Palo Alto CA, US
Ivan Tzvetanov - Palo Alto CA, US
Steven L. Herbowy - Palo Alto CA, US
Raj P. Ganpath - Mountain View CA, US
Amy Lee - Sunnyvale CA, US
Anant Kumar - San Jose CA, US
Gwendolyn A. Watanabe - Sunnyvale CA, US

Nellix, Inc. - Palo Alto CA

A61F 2/06
A61M 29/00

623 135, 606192

A system for treating an aneurysm in a blood vessel comprises a docking scaffold having with upstream and downstream ends, and a central passageway therebetween. The upstream end engages the blood vessel upstream of the aneurysm. A portion of a first and second scaffolds are slidably received in the central passageway such that an outside surface of the first and second scaffolds engage an inside surface of the docking scaffold. A double-walled filling structure has outer and inner walls and the filling structure is adapted to be filled with a hardenable fluid filling medium so that the outer wall conforms to an inside surface of the aneurysm and the inner wall forms a substantially tubular lumen to provide a path for blood flow therethrough. The double-walled filling structure is coupled with at least one of the first and second leg scaffolds in expanded configuration.

20100106087, Apr 29, 2010

Jan 7, 2010

12/684074

Michael A. Evans - Palo Alto CA, US
Gwendolyn A. Watanabe - Sunnyvale CA, US
Amy Lee - Sunnyvale CA, US
Steven L. Herbowy - Palo Alto CA, US

Nellix, Inc. - Palo Alto CA

A61M 29/00

60410303

Embodiments provide methods and systems for treating aneurysms using filling structures filled with a curable medium. An embodiment of a method comprises positioning at least one double-walled filling structure across the aneurysm and filling the structure(s) with a filling medium so that an outer wall conforms to the inside of the aneurysm and an inner wall forms a generally tubular lumen to provide for blood flow. The lumen is supported with a balloon or other expandable device while and/or after filling. The pressure within the structure and/or in the space between an external wall of the structure and the aneurysm wall is monitored and a flow of the medium into the structure is controlled responsive to the pressure. The pressure can also be used to determine a filling endpoint. The medium is hardened while the lumen remains supported by the balloon. The balloon is then removed after the medium hardens.