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Yuri Bereznitski Phones & Addresses

  • 78 Knob Hill Rd, Morganville, NJ 07751
  • Kent, OH
  • Metuchen, NJ
  • 40 Maklary St, South River, NJ 08882 (732) 254-9959
  • 78 Knob Hill Rd, Morganville, NJ 07751 (732) 254-9959

Work

Position: Private Household Service Occupations

Education

Degree: High school graduate or higher

Publications

Us Patents

Crystalline Forms Of An Inhibitor Of 11-Β-Hydroxysteroid Dehydrogenase Type 1

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US Patent:
8618112, Dec 31, 2013
Filed:
Dec 7, 2009
Appl. No.:
13/133516
Inventors:
Joseph E. Lynch - Plainfield NJ, US
Yuri Y. Bereznitski - South River NJ, US
Frederick T. Mattrey - Bridgewater NJ, US
Russell R. Ferlita - Tampa FL, US
Jinchu Liu - Edison NJ, US
Jungjun Yin - Green Brook NJ, US
Assignee:
Merck Sharp & Dohme Corp. - Rahway NJ
International Classification:
A61K 31/41
A61K 31/4196
C07D 249/08
C07D 401/04
US Classification:
514256, 514331, 514340, 514364, 544333, 548131, 548167, 548203, 5482662
Abstract:
Novel crystalline salts of 3-[4-(3-ethanesulfonyl-propyl)-bicyclo[2. 2. 2]oct-1-yl]-4-methyl-5-(2-trifluoromethyl-phenyl)-4H-1,2,4-triazole are potent inhibitors of 11β-hydroxysteroid dehydrogenase Type 1 and are useful for the treatment of conditions associated with Metabolic Syndrome as well as cognitive impairment. The invention also relates to pharmaceutical compositions containing these novel salts, processes to prepare these salts and their pharmaceutical compositions as well as uses thereof for the treatment of Type 2 diabetes, hyperglycemia, obesity, dyslipidemia, hypertension, and cognitive impairment.

Novel Crystalline Forms Of An Inhibitor Of 11-Beta-Hydroxysteroid Dehydrogenase Type 1

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US Patent:
20090186928, Jul 23, 2009
Filed:
Jan 21, 2005
Appl. No.:
10/587110
Inventors:
Yuri Bereznitski - South River NJ, US
Mark A. Huffman - Warren NJ, US
Joseph E. Lynch - Plainfield NJ, US
Matthew Zhao - Edison NJ, US
International Classification:
A61K 31/4196
C07D 249/08
A61P 3/10
US Classification:
514383, 5482622
Abstract:
Novel crystalline salts of 3-[1-(4-chlorophenyl)-trans-3-fluorocyclobutyl]-4,5-dicyclopropyl-r-4H-1,2,4-triazole are potent inhibitors of 11β-hydroxysteroid dehydrogenase Type 1 and are useful for the treatment of conditions associated with Metabolic Syndrome as well as cognitive impairment. The invention also relates to pharmaceutical compositions containing these novel salts, processes to prepare these salts and their pharmaceutical compositions as well as uses thereof for the treatment of Type 2 diabetes, hyperglycemia, obesity, dyslipidemia, hypertension, and cognitive impairment.
Yuri V Bereznitski from Morganville, NJ, age ~54 Get Report