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Kening R Song

from Acton, MA
Age ~68

Kening Song Phones & Addresses

  • 112 Willow St, Acton, MA 01720 (978) 263-8378
  • Forestdale, MA
  • 10 Patrick St, Arlington, MA 02474 (781) 648-7346
  • Pittsburgh, PA
  • Seattle, WA

Resumes

Resumes

Kening Song Photo 1

Principal Scientist

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Location:
440 1St St northwest, Washington, DC 20001
Industry:
Biotechnology
Work:
Shire
Principal Scientist

Eisai 2012 - 2013
Senior Scientist

Stryker 2006 - 2011
Principal Scientist

Pfizer 1997 - 2005
Staff Scientist Ii

University of Washington Hhmi 1995 - 1997
Postdoc
Education:
Boston University School of Medicine
Doctorates, Doctor of Philosophy, Biochemistry
Chinese Academy of Sciences
Master of Science, Masters, Biochemistry
Beijing Normal University
Bachelors, Bachelor of Science, Biology
Skills:
Cell Line and Assay Development
Celluar and Molecular Biology
Protein Engineering and Expression
Bone and Muscle
Biologics Process Development
Kening Song Photo 2

Kening Song

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Publications

Us Patents

Neutralizing Antibodies Against Gdf-8 And Uses Therefor

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US Patent:
8420082, Apr 16, 2013
Filed:
Dec 7, 2009
Appl. No.:
12/632383
Inventors:
Geertruida M. Veldman - Sudbury MA, US
Monique V. Davies - Harpswell MA, US
Kening Song - Arlington MA, US
Neil M. Wolfman - Dover MA, US
Kristie Grove Bridges - Maynard MA, US
Anne Field - Royston, GB
Caroline Russell - Royston, GB
Viia Valge-Archer - Little Abington, GB
Assignee:
Wyeth LLC - Wilmington DE
International Classification:
A61K 39/00
A61K 39/395
C07K 16/00
C07K 16/18
C07K 16/22
US Classification:
4241301, 4241331, 4241351, 4241411, 4241421, 4241451, 4241581, 5303871, 5303873, 5303881, 53038815, 53038823, 53038824
Abstract:
The disclosure provides novel antibodies against growth and differentiation factor-8 (GDF-8), in particular human antibodies, and antibody fragments, including those that inhibit GDF-8 activity in vitro and/or in vivo. The disclosure also provides methods for diagnosing, preventing, or treating degenerative disorders of muscle or bone, or disorders of insulin metabolism.

Neutralizing Antibodies Against Gdf-8 And Uses Therefor

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US Patent:
7261893, Aug 28, 2007
Filed:
Oct 21, 2003
Appl. No.:
10/688925
Inventors:
Geertruida M. Veldman - Sudbury MA, US
Monique V. Davies - Harpswell ME, US
Kening Song - Arlington MA, US
Neil M. Wolfman - Dover MA, US
Kristie Grove Bridges - Maynard MA, US
Anne Field - Herts, GB
Caroline Russell - Herts, GB
Viia Valge-Archer - Cambs, GB
Assignee:
Wyeth - Madison NJ
Cambridge Antibody Technology Limited - Cambridge
International Classification:
A61K 39/395
C12P 21/08
US Classification:
4241451, 4241411, 53038823, 53038824, 5303881
Abstract:
The disclosure provides novel antibodies against growth and differentiation factor-8 (GDF-8), in particular human antibodies, and antibody fragments, including those that inhibit GDF-8 activity in vitro and/or in vivo. The disclosure also provides methods for diagnosing, preventing, or treating degenerative disorders of muscle or bone, or disorders of insulin metabolism.

Neutralizing Antibodies Against Gdf-8 And Uses Therefor

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US Patent:
20080044410, Feb 21, 2008
Filed:
Jul 13, 2007
Appl. No.:
11/777525
Inventors:
Geertruida Veldman - Sudbury MA, US
Monique Davies - Harpswell ME, US
Kening Song - Arlington MA, US
Neil Wolfman - Dover MA, US
Kristie Bridges - Maynard MA, US
Anne Field - Royston, GB
Caroline Russell - Royston, GB
Viia Valge-Archer - Little Abington, GB
Assignee:
Wyeth - Madison NJ
Cambridge Antibody Technology Limited - Cambridge
International Classification:
A61K 39/395
A61P 19/00
A61P 19/08
A61P 21/00
C07H 21/02
C07H 21/04
C07K 16/22
C07K 16/44
C12N 15/85
C12N 5/10
US Classification:
424133100, 435320100, 435325000, 530387900, 530388150, 536023530
Abstract:
The disclosure provides novel antibodies against growth and differentiation factor-8 (GDF-8), in particular human antibodies, and antibody fragments, including those that inhibit GDF-8 activity in vitro and/or in vivo. The disclosure also provides methods for diagnosing, preventing, or treating degenerative disorders of muscle or bone, or disorders of insulin metabolism.

Bmp Mutants With Decreased Susceptibility To Noggin

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US Patent:
20110039773, Feb 17, 2011
Filed:
Dec 19, 2008
Appl. No.:
12/746821
Inventors:
Moulay Hicham Alaoui-Ismaili - Hopkinton MA, US
Kening Song - Acton MA, US
Assignee:
Stryker Biotech - Hopkinton MA
International Classification:
A61K 38/18
C07K 14/51
C07K 14/475
C07H 21/00
C12N 15/63
A61P 19/08
A61P 19/04
US Classification:
514 88, 530350, 514 76, 536 235, 4353201
Abstract:
The present invention provides modified, highly potent bone morphogenetic proteins. In particular, the present invention relates to the observation that BMP-6 and BMP-9 are less susceptible to inhibition by Noggin that are other members of the BMP subfamily of proteins. The present invention features chimeric bone morphogenetic proteins in which the middle portion of BMP-6 or BMP-9 replaces the middle portion of another BMP subfamily protein to cause resistance to inhibition by Noggin or other Noggin-like antagonists. Other embodiments of modified BMPs, compositions and methods of use are also included.

Bmp Mutants With Decreased Susceptibility To Noggin

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US Patent:
20130184208, Jul 18, 2013
Filed:
Nov 30, 2012
Appl. No.:
13/690211
Inventors:
Moulay Hicham Alaoui-Ismaili - San Mateo CA, US
Kening Song - Acton MA, US
International Classification:
C07K 14/51
US Classification:
514 88, 530399, 536 235, 4353201
Abstract:
The present invention provides modified, highly potent bone morphogenetic proteins. In particular, the present invention relates to the observation that BMP-6 and BMP-9 are less susceptible to inhibition by Noggin that are other members of the BMP subfamily of proteins. The present invention features chimeric bone morphogenetic proteins in which the middle portion of BMP-6 or BMP-9 replaces the middle portion of another BMP subfamily protein to cause resistance to inhibition by Noggin or other Noggin-like antagonists. Other embodiments of modified BMPs, compositions and methods of use are also included.

Neutralizing Antibodies Against Gdf-8 And Uses Therefor

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US Patent:
20130287762, Oct 31, 2013
Filed:
Nov 30, 2012
Appl. No.:
13/691395
Inventors:
Geetruida M. Veldman - Sudbury MA, US
Monique V. Davies - Harpswell MA, US
Kening Song - Arlington MA, US
Neil M. Wolfman - Dover MA, US
Kristie Grove - Maynard MA, US
Anne Field - Rayston, GB
Caroline Russell - Royston, GB
Viia Valge-Archer - Little Abington, GB
Assignee:
MEDIMMUNE LIMITED - CAMBRIDGE
WYETH - MADISON NJ
International Classification:
C07K 16/22
US Classification:
4241331, 5303892, 5303873, 4241581, 536 2353, 4353201, 435336, 435 696, 4352523, 4352542
Abstract:
The disclosure provides novel antibodies against growth and differentiation factor-8 (GDF-8), in particular human antibodies, and antibody fragments, including those that inhibit GDF-8 activity in vitro and/or in vivo. The disclosure also provides methods for diagnosing, preventing, or treating degenerative disorders of muscle or bone, or disorders of insulin metabolism.
Kening R Song from Acton, MA, age ~68 Get Report