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Lucia Santacruz Phones & Addresses

  • Bethesda, MD
  • Chapel Hill, NC
  • Torrance, CA
  • Durham, NC
  • Lutz, FL
  • Pearland, TX
  • Raleigh, NC
  • Los Angeles, CA
  • Redondo Beach, CA

Publications

Us Patents

Compositions And Methods For Detecting Cardiotoxicity

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US Patent:
2012031, Dec 13, 2012
Filed:
Jun 8, 2012
Appl. No.:
13/492072
Inventors:
Lucia A. Santacruz Kozarinas - Chapel Hill NC,
Danny O. Jacobs - Durham NC,
Assignee:
DUKE UNIVERSITY - Durham NC
International Classification:
G01N 33/566
G01N 21/64
G01N 21/76
G01N 33/577
US Classification:
435 725, 435 721
Abstract:
The present disclosure provides methods and compositions for detecting the presence and activity of creatine transporter proteins (CrT) in biological samples comprising screening the samples for CrT using antibodies that bind to the CrT. The methods are useful to detect the onset of cardiotoxicity in subjects undergoing treatment with anthrocyclines or those susceptible to heart-related conditions. The methods and compositions described herein in can be practiced with diagnostic kits.
Lucia Santacruz from Bethesda, MD, age ~54 Get Report