Inventors:
Philip R. Kym - Grayslake IL
Kresna Hartandi - Gurnee IL
Ju Gao - Gurnee IL
Kathleen M. Phelan - Gurnee IL
Christine A. Collins - Skokie IL
Anil Vasudevan - Gurnee IL
Mary K. Verzal - Burlington WI
Assignee:
Abbott Laboratories - Abbott Park IL
International Classification:
C07D21538
Abstract:
The present invention relates to the antagonism of the effects of melanin-concentrating hormone (MCH) through the melanin concentrating hormone receptor which is useful for the prevention or treatment of eating disorders, weight gain, obesity, abnormalities in reproduction and sexual behavior, thyroid hormone secretion, diuresis and water/electrolyte homeostasis, sensory processing, memory, sleeping, arousal, anxiety, depression, seizures, neurodegeneration and psychiatric disorders.