US Patent:
20220411875, Dec 29, 2022
Inventors:
- San Carlos CA, US
Matthew Micah HILL - Belmont CA, US
Bernhard ZIMMERMANN - Manteca CA, US
Johan BANER - San Francisco CA, US
George GEMELOS - Portland OR, US
Milena BANJEVIC - Los Altos Hills CA, US
Allison RYAN - Belmont CA, US
Styrmir SIGURJONSSON - San Jose CA, US
Zachary DEMKO - San Francisco CA, US
Assignee:
Natera, Inc. - San Carlos CA
International Classification:
C12Q 1/6883
C12Q 1/6811
C12Q 1/6848
C12Q 1/6809
C12Q 1/6851
C12Q 1/6844
C12Q 1/6869
C12Q 1/6855
C12Q 1/6874
Abstract:
The invention provides methods for simultaneously amplifying multiple nucleic acid regions of interest in one reaction volume as well as methods for selecting a library of primers for use in such amplification methods. The invention also provides library of primers with desirable characteristics, such as minimal formation of amplified primer dimers or other non-target amplicons.